KEGG   ORTHOLOGY: K05119Help
Entry
K05119                      KO                                     

Name
ALK, CD246
Definition
anaplastic lymphoma kinase [EC:2.7.10.1]
Pathway
Non-small cell lung cancer
Disease
H00014  
Non-small cell lung cancer
H01601  
Anaplastic large-cell lymphoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Human Diseases
  Cancers
   05223 Non-small cell lung cancer
    K05119  ALK, CD246; anaplastic lymphoma kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05119  ALK, CD246; anaplastic lymphoma kinase
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  Alk family
   K05119  ALK, CD246; anaplastic lymphoma kinase
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class X (LTK receptor family)
   K05119  ALK, CD246; anaplastic lymphoma kinase
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class X (LTK receptor family)
   K05119  ALK, CD246; anaplastic lymphoma kinase
Cellular antigens [BR:ko04090]
 Proteins
  K05119  CD246, ALK; anaplastic lymphoma kinase (Ki-1)
BRITE hierarchy
Genes
HSA: 
238(ALK)
PTR: 
459127(ALK)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
704601(ALK) 704823(ALK)
MCF: 
CSAB: 
RRO: 
CJC: 
SBQ: 
MMU: 
11682(Alk)
RNO: 
266802(Alk)
CGE: 
NGI: 
HGL: 
OCU: 
TUP: 
CFA: 
483021(ALK)
AML: 
UMR: 
FCA: 
PTG: 
BTA: 
536642(ALK)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
LAV: 
MDO: 
SHR: 
OAA: 
GGA: 
421297(ALK) 423216(LTK)
MGP: 
CJO: 
APLA: 
TGU: 
GFR: 
FAB: 
PHI: 
CCW: 
FPG: 
FCH: 
CLV: 
AAM: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
GJA: 
XTR: 
DRE: 
563509(alk) 564470(ltk)
TRU: 
TNG: 
MZE: 
OLA: 
XMA: 
SASA: 
LCM: 
CMK: 
BFO: 
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD25528(Dsim_GD25528)
DWI: 
DYA: 
Dyak_GE14049(dyak_GLEANR_14204)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
BIM: 
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
TCA: 
BMOR: 
DPL: 
PXY: 
API: 
PHU: 
DPX: 
ISC: 
CEL: 
CBR: 
CBG18982(Cbr-scd-2)
BMY: 
LOA: 
TSP: 
LGI: 
CRG: 
OBI: 
AQU: 
SRE: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9174053
  Authors
Morris SW, Naeve C, Mathew P, James PL, Kirstein MN, Cui X, Witte DP
  Title
ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)
  Journal
Oncogene 14:2175-88 (1997)
  Sequence
[hsa:238]
Reference
  Authors
Palmer RH, Vernersson E, Grabbe C, Hallberg B
  Title
Anaplastic lymphoma kinase: signalling in development and disease.
  Journal
Biochem J 420:345-61 (2009)

DBGET integrated database retrieval system