KEGG   ORTHOLOGY: K05121Help
Entry
K05121                      KO                                     

Name
TEK, TIE2
Definition
endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
Pathway
Ras signaling pathway
Rap1 signaling pathway
HIF-1 signaling pathway
PI3K-Akt signaling pathway
Rheumatoid arthritis
Disease
H00531  
Venous malformations
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase
   04015 Rap1 signaling pathway
    K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase
   04066 HIF-1 signaling pathway
    K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase
   04151 PI3K-Akt signaling pathway
    K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase
 Human Diseases
  Immune diseases
   05323 Rheumatoid arthritis
    K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  Tie family
   K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class XI (TIE receptor family)
   K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class XI (TIE receptor family)
   K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase
Cellular antigens [BR:ko04090]
 Proteins
  K05121  CD202b, TEK; TEK tyrosine kinase, endothelial
BRITE hierarchy
Genes
HSA: 
7010(TEK)
PTR: 
465028(TEK)
PPS: 
GGO: 
PON: 
100189890(DKFZP469L125)
MCC: 
707455(TEK)
MCF: 
MMU: 
21687(Tek)
RNO: 
89804(Tek)
CGE: 
HGL: 
TUP: 
CFA: 
403714(TEK)
AML: 
FCA: 
BTA: 
280939(TEK)
BOM: 
PHD: 
CHX: 
SSC: 
396729(TEK)
CFR: 
ECB: 
MYB: 
MDO: 
SHR: 
OAA: 
GGA: 
427368(TEK)
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
PSS: 
ACS: 
XTR: 
DRE: 
30747(tek)
LCM: 
BFO: 
CIN: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Puri MC, Bernstein A
  Title
Requirement for the TIE family of receptor tyrosine kinases in adult but not fetal hematopoiesis.
  Journal
Proc Natl Acad Sci U S A 100:12753-8 (2003)

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