KEGG   ORTHOLOGY: K05132Help
Entry
K05132                      KO                                     

Name
IFNGR1, CD119
Definition
interferon gamma receptor 1
Pathway
Cytokine-cytokine receptor interaction
HIF-1 signaling pathway
Necroptosis
Osteoclast differentiation
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
Th1 and Th2 cell differentiation
Th17 cell differentiation
Salmonella infection
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Measles
Influenza A
Kaposi's sarcoma-associated herpesvirus infection
Herpes simplex infection
Inflammatory bowel disease (IBD)
Disease
H00089  
IFN-gamma/IL-12 axis
H00342  
Tuberculosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04066 HIF-1 signaling pathway
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05132  IFNGR1, CD119; interferon gamma receptor 1
 Cellular Processes
  Cell growth and death
   04217 Necroptosis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04658 Th1 and Th2 cell differentiation
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04659 Th17 cell differentiation
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  Development
   04380 Osteoclast differentiation
    K05132  IFNGR1, CD119; interferon gamma receptor 1
 Human Diseases
  Immune diseases
   05321 Inflammatiory bowel disease (IBD)
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  Infectious diseases
   05132 Salmonella infection
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05152 Tuberculosis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05162 Measles
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05164 Influenza A
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05168 Herpes simplex infection
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05145 Toxoplasmosis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05140 Leishmaniasis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05142 Chagas disease (American trypanosomiasis)
    K05132  IFNGR1, CD119; interferon gamma receptor 1
Cytokine receptors [BR:ko04050]
 Class II cytokine receptor (interferon/IL-10 family receptor)
  K05132  IFNGR1, CD119; interferon gamma receptor 1
Cellular antigens [BR:ko04090]
 Proteins
  K05132  CD119, IFNGR1; interferon gamma receptor 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
3459(IFNGR1)
PTR: 
747276(IFNGR1)
PPS: 
100994342(IFNGR1)
GGO: 
101150227(IFNGR1)
PON: 
100171593(IFNGR1)
NLE: 
100598615(IFNGR1)
MCC: 
100423877(IFNGR1)
MCF: 
101866179(IFNGR1)
CSAB: 
103240303(IFNGR1)
RRO: 
104675021(IFNGR1)
CJC: 
100386516(IFNGR1)
SBQ: 
101054160(IFNGR1)
MMU: 
15979(Ifngr1)
RNO: 
116465(Ifngr1)
CGE: 
100772793(Ifngr1)
NGI: 
103724895(Ifngr1)
HGL: 
101709169(Ifngr1)
OCU: 
100341787(IFNGR1)
TUP: 
102475588(IFNGR1)
CFA: 
100856077(IFNGR1)
AML: 
100473768(IFNGR1)
UMR: 
103663370(IFNGR1)
FCA: 
101086811(IFNGR1)
PTG: 
102952498(IFNGR1)
AJU: 
106985768(IFNGR1)
BTA: 
508619(IFNGR1)
BOM: 
102275527(IFNGR1)
PHD: 
102319213(IFNGR1)
CHX: 
102182698(IFNGR1)
OAS: 
101112907(IFNGR1)
SSC: 
100152238(IFNGR1)
CFR: 
102522759(IFNGR1)
BACU: 
103000886(IFNGR1)
LVE: 
103082113(IFNGR1)
ECB: 
100073195(IFNGR1)
MYB: 
102258073(IFNGR1)
MYD: 
102761556(IFNGR1)
HAI: 
109376141 109385640(IFNGR1)
PALE: 
102888010(IFNGR1)
LAV: 
100665172(IFNGR1)
MDO: 
100031565(IFNGR1)
SHR: 
100928392(IFNGR1)
OAA: 
100078574(IFNGR1)
GGA: 
421685(IFNGR1)
MGP: 
100550637(IFNGR1)
CJO: 
107311677(IFNGR1)
APLA: 
101799854(IFNGR1)
TGU: 
100222262(IFNGR1)
GFR: 
102034996(IFNGR1)
FAB: 
101813223(IFNGR1)
PHI: 
102104751(IFNGR1)
CCW: 
104689508(IFNGR1)
FPG: 
101911079(IFNGR1)
FCH: 
102048414(IFNGR1)
CLV: 
102085405(IFNGR1)
AAM: 
106497894(IFNGR1)
ASN: 
102374995(IFNGR1)
AMJ: 
102566228(IFNGR1)
PSS: 
102448524(IFNGR1)
CMY: 
102936486(IFNGR1)
CPIC: 
101945033(IFNGR1)
ACS: 
103279436(ifngr1)
PBI: 
103056914(IFNGR1)
GJA: 
107121392(IFNGR1)
XLA: 
108717881
XTR: 
780275(ifngr1)
DRE: 
100329124(ifngr1)
TRU: 
105416329(ifngr1)
SASA: 
106587463 106589674(ifngr1) 106589675
LCM: 
102362892(IFNGR1)
CMK: 
103178319
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2971451
  Authors
Aguet M, Dembic Z, Merlin G
  Title
Molecular cloning and expression of the human interferon-gamma receptor.
  Journal
Cell 55:273-80 (1988)
DOI:10.1016/0092-8674(88)90050-5
  Sequence
[hsa:3459]
Reference
  Authors
Donnelly RP, Sheikh F, Kotenko SV, Dickensheets H
  Title
The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain.
  Journal
J Leukoc Biol 76:314-21 (2004)
DOI:10.1189/jlb.0204117
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