KEGG ORTHOLOGY: K05133

ORTHOLOGY: K05133

Entry

K05133                      KO

Symbol

IFNGR2

Name

interferon gamma receptor 2

Pathway

map04060

Cytokine-cytokine receptor interaction

map04066

HIF-1 signaling pathway

map04217

Necroptosis

map04380

Osteoclast differentiation

map04630

JAK-STAT signaling pathway

map04650

Natural killer cell mediated cytotoxicity

map04658

Th1 and Th2 cell differentiation

map04659

Th17 cell differentiation

map05140

Leishmaniasis

map05142

Chagas disease

map05145

Toxoplasmosis

map05152

Tuberculosis

map05164

Influenza A

map05168

Herpes simplex virus 1 infection

map05200

Pathways in cancer

map05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

map05321

Inflammatory bowel disease

Disease

H00089

IFN-gamma/IL-12 axis

H00342

Tuberculosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05133  IFNGR2; interferon gamma receptor 2
   04066 HIF-1 signaling pathway
    K05133  IFNGR2; interferon gamma receptor 2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05133  IFNGR2; interferon gamma receptor 2
09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05133  IFNGR2; interferon gamma receptor 2
09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K05133  IFNGR2; interferon gamma receptor 2
   04658 Th1 and Th2 cell differentiation
    K05133  IFNGR2; interferon gamma receptor 2
   04659 Th17 cell differentiation
    K05133  IFNGR2; interferon gamma receptor 2
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05133  IFNGR2; interferon gamma receptor 2
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05133  IFNGR2; interferon gamma receptor 2
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K05133  IFNGR2; interferon gamma receptor 2
  09172 Infectious disease: viral
   05164 Influenza A
    K05133  IFNGR2; interferon gamma receptor 2
   05168 Herpes simplex virus 1 infection
    K05133  IFNGR2; interferon gamma receptor 2
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K05133  IFNGR2; interferon gamma receptor 2
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K05133  IFNGR2; interferon gamma receptor 2
   05140 Leishmaniasis
    K05133  IFNGR2; interferon gamma receptor 2
   05142 Chagas disease
    K05133  IFNGR2; interferon gamma receptor 2
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05133  IFNGR2; interferon gamma receptor 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05133  IFNGR2; interferon gamma receptor 2
Cytokine receptors [BR:ko04050]
Interleukin receptor families
  IFN receptor family
   K05133  IFNGR2; interferon gamma receptor 2

Other DBs

GO:

0004906

Genes

HSA:	3460(IFNGR2)

PTR:	470077(IFNGR2)

PPS:	100988947(IFNGR2)

GGO:	101144355(IFNGR2)

PON:	100442383(IFNGR2)

NLE:	105738709(IFNGR2)

HMH:	116482637(IFNGR2)

MCC:	699489(IFNGR2)

MCF:	102138221(IFNGR2)

MTHB:

126951668

MNI:	105472941(IFNGR2)

CSAB:

103216867(IFNGR2)

CATY:

105575379(IFNGR2)

PANU:

100137246(IFNGR2)

TGE:	112620311(IFNGR2)

MLEU:

105553170(IFNGR2)

RRO:	104658778(IFNGR2)

RBB:	108536857(IFNGR2)

TFN:	117095714(IFNGR2)

PTEH:

111525329(IFNGR2)

CANG:

105524763(IFNGR2)

CJC:	100389763(IFNGR2)

SBQ:	101050965(IFNGR2)

CIMI:

108302512(IFNGR2)

CSYR:

103269363(IFNGR2)

MMUR:

105861514(IFNGR2)

LCAT:

123630699(IFNGR2)

PCOQ:

105820775(IFNGR2)

OGA:	100957974(IFNGR2)

MMU:	15980(Ifngr2)

MCAL:

110311588(Ifngr2)

MPAH:

110330069(Ifngr2)

RNO:	360697(Ifngr2)

MCOC:

116086134(Ifngr2)

ANU:	117718220(Ifngr2)

MUN:	110541673(Ifngr2)

CGE:	100768877(Ifngr2)

MAUA:

101828108(Ifngr2)

PROB:

127227515(Ifngr2)

PLEU:

114698434(Ifngr2)

MORG:

121461788(Ifngr2)

MFOT:

126515265

AAMP:

119825404(Ifngr2)

NGI:	103736453(Ifngr2)

HGL:	101724858(Ifngr2)

CPOC:

100714935(Ifngr2)

CCAN:

109686803(Ifngr2)

DORD:

105994023(Ifngr2)

DSP:	122114285(Ifngr2)

PLOP:

125351499(Ifngr2)

NCAR:

124992912

MMMA:

107136144(Ifngr2)

OCU:

100338854

OPI:	101527415(IFNGR2)

TUP:	102481577(IFNGR2)

GVR:	103585995(IFNGR2)

CFA:	487739(IFNGR2)

CLUD:

112661608(IFNGR2)

VVP:	112909266(IFNGR2)

VLG:	121479429(IFNGR2)

NPO:	129502066(IFNGR2)

AML:	100481672(IFNGR2)

UMR:	103673221(IFNGR2)

UAH:	113264675(IFNGR2)

UAR:	123784207(IFNGR2)

ELK:

111155682

LLV:

125095012

MPUF:

101673958(IFNGR2)

MNP:	132012363(IFNGR2)

MLK:	131825325(IFNGR2)

NVS:	122908329(IFNGR2)

EJU:	114218085(IFNGR2)

ZCA:	113918583(IFNGR2)

MLX:	118018832(IFNGR2)

NSU:	110570023(IFNGR2)

LWW:	102748762(IFNGR2)

FCA:	101092286(IFNGR2)

PYU:	121035991(IFNGR2)

PCOO:

112849760(IFNGR2)

PBG:	122491220(IFNGR2)

PVIV:

125174887(IFNGR2)

LRUF:

124526582

PTG:	102955729(IFNGR2)

PPAD:

109249716(IFNGR2)

PUC:

125921709

AJU:

106966456

HHV:	120229426(IFNGR2)

BTA:	514889(IFNGR2)

BOM:	102281523(IFNGR2)

BIU:	109569763(IFNGR2)

BBUB:

102393764(IFNGR2)

BBIS:

105004619(IFNGR2)

CHX:	102191269(IFNGR2)

OAS:	101122484(IFNGR2)

BTAX:

128047334(IFNGR2)

ODA:	120854372(IFNGR2)

CCAD:

122428752(IFNGR2)

MBEZ:

129552631(IFNGR2)

SSC:	100126864(IFNGR2)

CFR:	102523264(IFNGR2)

CBAI:

105070232(IFNGR2)

CDK:	105089867(IFNGR2)

VPC:	102531183(IFNGR2)

BACU:

102997804(IFNGR2)

BMUS:

118894350(IFNGR2)

LVE:	103081741(IFNGR2)

OOR:	101279441(IFNGR2)

DLE:	111163885(IFNGR2)

PCAD:

102997040(IFNGR2)

PSIU:

116752565(IFNGR2)

NASI:

112408543(IFNGR2)

ECB:	100063333(IFNGR2)

EPZ:	103549109(IFNGR2)

EAI:	106832838(IFNGR2)

MYB:	102260069(IFNGR2)

MYD:	102751646(IFNGR2)

MMYO:

118675501(IFNGR2)

MLF:	102422535(IFNGR2)

PKL:	118716064(IFNGR2)

EFUS:

103289926(IFNGR2)

MNA:	107537453(IFNGR2)

DRO:	112308734(IFNGR2)

SHON:

119000289(IFNGR2)

AJM:	119035735(IFNGR2)

PDIC:

118498608(IFNGR2)

PHAS:

123828042(IFNGR2)

MMF:	118617140(IFNGR2)

PPAM:

129072512(IFNGR2)

HAI:	109373230(IFNGR2)

RFQ:	117036042(IFNGR2)

PALE:

102877930(IFNGR2)

PGIG:

120598794(IFNGR2)

PVP:	105295851(IFNGR2)

RAY:	107519538(IFNGR2)

MJV:	108385993(IFNGR2)

TOD:	119257088(IFNGR2)

SARA:

101558386(IFNGR2)

SETR:

126026073(IFNGR2)

LAV:	100667304(IFNGR2)

TMU:

101361970

ETF:	101640830(IFNGR2)

DNM:	101425494(IFNGR2)

MDO:	103106298(IFNGR2)

GAS:	123242452(IFNGR2)

SHR:	100929576(IFNGR2)

AFZ:

127553870

PCW:	110214784(IFNGR2)

OAA:	100083438(IFNGR2)

GGA:	418502(IFNGR2)

PCOC:

116242121(IFNGR2)

MGP:	100542511(IFNGR2)

CJO:	107323014(IFNGR2)

TPAI:

128076355(IFNGR2)

LMUT:

125697195(IFNGR2)

NMEL:

110402478(IFNGR2)

APLA:

101790789(IFNGR2)

ACYG:

106043434(IFNGR2)

CATA:

118247661(IFNGR2)

AFUL:

116488163(IFNGR2)

TGU:	100217912(IFNGR2)

SCAN:

103824420(IFNGR2)

PMOA:

120503406(IFNGR2)

OTC:

121334745

PRUF:

121356336(IFNGR2)

GFR:	102044820(IFNGR2)

FAB:	101814771(IFNGR2)

OMA:	130252009(IFNGR2)

PHI:

102110714

PMAJ:

107199716

CCAE:

111929263

CCW:	104698064(IFNGR2)

CBRC:

103621834(IFNGR2)

ETL:

114072364

ACHL:

103803230(IFNGR2)

SVG:	106861742(IFNGR2)

MMEA:

130583755

HRT:	120749097(IFNGR2)

FPG:	101919933(IFNGR2)

FCH:	102054741(IFNGR2)

CLV:	102097051(IFNGR2)

EGZ:	104128225(IFNGR2)

NNI:	104020120(IFNGR2)

PCRI:

104030404(IFNGR2)

PLET:

104627150(IFNGR2)

PCAO:

104044565 104052259

ACUN:

113477857(IFNGR2)

TALA:

104359820(IFNGR2)

PADL:

103920255(IFNGR2)

AFOR:

103901968(IFNGR2)

ACHC:

115343830(IFNGR2)

HALD:

104315189(IFNGR2)

HLE:	104835890(IFNGR2)

AGEN:

126053194

GCL:

127029452

CCRI:

104167679(IFNGR2)

CSTI:

104551797(IFNGR2)

CMAC:

104474922(IFNGR2)

MUI:	104535234(IFNGR2)

BREG:

104631125(IFNGR2)

FGA:	104070905(IFNGR2)

GSTE:

104252480(IFNGR2)

LDI:	104341618(IFNGR2)

MNB:	103773877(IFNGR2)

OHA:	104328368(IFNGR2)

NNT:	104403388(IFNGR2)

SHAB:

115601539(IFNGR2)

DPUB:

104306429(IFNGR2)

PGUU:

104459971(IFNGR2)

ACAR:

104521006(IFNGR2)

CPEA:

104395004(IFNGR2)

AVIT:

104271752

CVF:	104295175(IFNGR2)

RTD:	128907471(IFNGR2)

CUCA:

104064789(IFNGR2)

TEO:	104379546(IFNGR2)

BRHI:

104488528(IFNGR2)

AAM:	106494952(IFNGR2)

AROW:

112971821(IFNGR2)

NPD:	112953613(IFNGR2)

TGT:	104566672(IFNGR2)

DNE:	112988215(IFNGR2)

SCAM:

104139451(IFNGR2)

ASN:	102384623(IFNGR2)

AMJ:	102568595(IFNGR2)

CPOO:

109305779(IFNGR2)

GGN:	109302329(IFNGR2)

PSS:	102452317(IFNGR2)

CMY:	102929704(IFNGR2)

CCAY:

125644251(IFNGR2)

DCC:	119849712(IFNGR2)

CPIC:

101942504(IFNGR2)

TST:	117867154(IFNGR2)

CABI:

116829957(IFNGR2)

MRV:	120398127(IFNGR2)

ACS:	103278369(ifngr2)

ASAO:

132771879

PVT:	110080392(IFNGR2)

SUND:

121926273(IFNGR2)

PBI:	103049152(IFNGR2)

PMUR:

107290470(IFNGR2)

CTIG:

120296956

TSR:

106546647

PGUT:

117676037(IFNGR2)

APRI:

131199419(IFNGR2)

PTEX:

113436268(IFNGR2)

VKO:	123029099(IFNGR2)

PMUA:

114596051(IFNGR2)

PRAF:

128412985(IFNGR2)

ZVI:	118084879(IFNGR2)

HCG:	128349113(IFNGR2)

GJA:	107121928(IFNGR2)

STOW:

125430734(IFNGR2)

EMC:	129325489(IFNGR2)

XLA:	100037016 100101283 108707874 108707875

XTR:	100485298(ifngr2.2) 100485464(ifngr2.1)

RTEM:

120927904(IFNGR2)

BBUF:

120994525

BGAR:

122930810

MUO:	115458909 115469739(IFNGR2)

GSH:	117362610(IFNGR2)

SRX:

SANH:

SGH:

CCAR:

AMEX:

ONL:	109194437(ifngr2-2)

OAU:

116314989

GAF:	122839747(ifngr2)

CSEM:

103391492

POV:

109637424

SSEN:

122765129

LCF:	108897140(ifngr2)

SDU:

111228112

SLAL:

111663447

XGL:	120801444(ifngr2)

MALB:

109951993

SASA:

106581880 106586855(IFNGR2)

OTW:	112225269 112243284

OMY:	100301644(ifngr2a) 110501419(ifngr2b)

SALP:

111959969 112069301

SFM:	108922312(ifngr2)

PKI:

AANG:

LOC:

ARUT:

Reference

PMID:8124716

Authors

Soh J, Donnelly RJ, Kotenko S, Mariano TM, Cook JR, Wang N, Emanuel S, Schwartz B, Miki T, Pestka S

Title

Identification and sequence of an accessory factor required for activation of the human interferon gamma receptor.

Journal

Cell 76:793-802 (1994)
DOI:10.1016/0092-8674(94)90354-9

Sequence

[hsa:3460]

Reference

PMID:11282540

Authors

Bernabei P, Allione A, Rigamonti L, Bosticardo M, Losana G, Borghi I, Forni G, Novelli F

Title

Regulation of interferon-gamma receptor (INF-gammaR) chains: a peculiar way to rule the life and death of human lymphocytes.

Journal

Eur Cytokine Netw 12:6-14 (2001)

All links

Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (34)   
   KEGG PATHWAY (34)   
Disease (2)   
   KEGG DISEASE (2)   
Drug (3)   
   KEGG DRUG (3)   
Gene (300)   
   KEGG GENES (295)   
   RefGene (2)   
   OC (3)   
Literature (2)   
   PubMed (2)   
All databases (344)   

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