KEGG   ORTHOLOGY: K05133Help
Entry
K05133                      KO                                     

Name
IFNGR2
Definition
interferon gamma receptor 2
Pathway
Cytokine-cytokine receptor interaction
HIF-1 signaling pathway
Necroptosis
Osteoclast differentiation
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
Th1 and Th2 cell differentiation
Th17 cell differentiation
Salmonella infection
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Measles
Influenza A
Herpes simplex infection
Inflammatory bowel disease (IBD)
Disease
H00089  
IFN-gamma/IL-12 axis
H00342  
Tuberculosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05133  IFNGR2; interferon gamma receptor 2
   04066 HIF-1 signaling pathway
    K05133  IFNGR2; interferon gamma receptor 2
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05133  IFNGR2; interferon gamma receptor 2
 Cellular Processes
  Cell growth and death
   04217 Necroptosis
    K05133  IFNGR2; interferon gamma receptor 2
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K05133  IFNGR2; interferon gamma receptor 2
   04658 Th1 and Th2 cell differentiation
    K05133  IFNGR2; interferon gamma receptor 2
   04659 Th17 cell differentiation
    K05133  IFNGR2; interferon gamma receptor 2
  Development
   04380 Osteoclast differentiation
    K05133  IFNGR2; interferon gamma receptor 2
 Human Diseases
  Immune diseases
   05321 Inflammatiory bowel disease (IBD)
    K05133  IFNGR2; interferon gamma receptor 2
  Infectious diseases
   05132 Salmonella infection
    K05133  IFNGR2; interferon gamma receptor 2
   05152 Tuberculosis
    K05133  IFNGR2; interferon gamma receptor 2
   05162 Measles
    K05133  IFNGR2; interferon gamma receptor 2
   05164 Influenza A
    K05133  IFNGR2; interferon gamma receptor 2
   05168 Herpes simplex infection
    K05133  IFNGR2; interferon gamma receptor 2
   05145 Toxoplasmosis
    K05133  IFNGR2; interferon gamma receptor 2
   05140 Leishmaniasis
    K05133  IFNGR2; interferon gamma receptor 2
   05142 Chagas disease (American trypanosomiasis)
    K05133  IFNGR2; interferon gamma receptor 2
Cytokine receptors [BR:ko04050]
 Class II cytokine receptor (interferon/IL-10 family receptor)
  K05133  IFNGR2; interferon gamma receptor 2
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
3460(IFNGR2)
PTR: 
470077(IFNGR2)
PPS: 
100988947(IFNGR2)
GGO: 
101144355(IFNGR2)
PON: 
100442383(IFNGR2)
NLE: 
105738709(IFNGR2)
MCC: 
699489(IFNGR2)
MCF: 
102138221(IFNGR2)
CSAB: 
103216867(IFNGR2)
RRO: 
104658778(IFNGR2)
CJC: 
100389763(IFNGR2)
SBQ: 
101050965(IFNGR2)
MMU: 
15980(Ifngr2)
RNO: 
360697(Ifngr2)
CGE: 
100768877(Ifngr2)
NGI: 
103736453(Ifngr2)
HGL: 
101724858(Ifngr2)
OCU: 
100338854(IFNGR2)
TUP: 
102481577(IFNGR2)
CFA: 
100856276(IFNGR2) 487739
AML: 
100481672(IFNGR2)
UMR: 
103673221(IFNGR2)
FCA: 
101092286(IFNGR2)
PTG: 
102955729(IFNGR2)
AJU: 
106966456(IFNGR2)
BTA: 
514889(IFNGR2)
BOM: 
102281523(IFNGR2)
PHD: 
102315128(IFNGR2)
CHX: 
102191269(IFNGR2)
OAS: 
101122484(IFNGR2)
SSC: 
100126864(IFNGR2)
CFR: 
102523264(IFNGR2)
BACU: 
102997804(IFNGR2)
LVE: 
103081741(IFNGR2)
ECB: 
100063333(IFNGR2)
MYB: 
102260069(IFNGR2)
MYD: 
102751646(IFNGR2)
HAI: 
109373230(IFNGR2)
PALE: 
102877930(IFNGR2)
LAV: 
100667304(IFNGR2)
MDO: 
103106298(IFNGR2)
SHR: 
100929576(IFNGR2)
OAA: 
100083438(IFNGR2)
GGA: 
418502(IFNGR2)
MGP: 
100542511(IFNGR2)
CJO: 
107323014(IFNGR2)
APLA: 
101790789(IFNGR2)
TGU: 
100217912(IFNGR2)
GFR: 
102044820(IFNGR2)
FAB: 
101814771(IFNGR2)
PHI: 
102110714(IFNGR2)
CCW: 
104698064
FPG: 
101919933(IFNGR2)
FCH: 
102054741(IFNGR2)
CLV: 
102097051(IFNGR2)
AAM: 
106494952(IFNGR2)
ASN: 
102384623(IFNGR2)
AMJ: 
102568595(IFNGR2)
PSS: 
102452317(IFNGR2)
CMY: 
102929704
CPIC: 
101942504(IFNGR2)
ACS: 
103278369(ifngr2)
PBI: 
103049152(IFNGR2)
GJA: 
107121928(IFNGR2)
XLA: 
100037016 100101283 108707874 108707875
XTR: 
100485298(ifngr2.2) 100485464(ifngr2.1)
SASA: 
106586855(IFNGR2)
LCM: 
102362749
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8124716
  Authors
Soh J, Donnelly RJ, Kotenko S, Mariano TM, Cook JR, Wang N, Emanuel S, Schwartz B, Miki T, Pestka S
  Title
Identification and sequence of an accessory factor required for activation of the human interferon gamma receptor.
  Journal
Cell 76:793-802 (1994)
DOI:10.1016/0092-8674(94)90354-9
  Sequence
[hsa:3460]
Reference
  Authors
Bernabei P, Allione A, Rigamonti L, Bosticardo M, Losana G, Borghi I, Forni G, Novelli F
  Title
Regulation of interferon-gamma receptor (INF-gammaR) chains: a peculiar way to rule the life and death of human lymphocytes.
  Journal
Eur Cytokine Netw 12:6-14 (2001)
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