KEGG ORTHOLOGY: K05208

ORTHOLOGY: K05208

Entry

K05208 KO

Name

GRIN1

Definition

glutamate receptor ionotropic, NMDA 1

Pathway

ko04020	Calcium signaling pathway
ko04080	Neuroactive ligand-receptor interaction
ko04713	Circadian entrainment
ko04720	Long-term potentiation
ko04724	Glutamatergic synapse
ko05010	Alzheimer's disease
ko05014	Amyotrophic lateral sclerosis (ALS)
ko05016	Huntington's disease
ko05030	Cocaine addiction
ko05031	Amphetamine addiction
ko05033	Nicotine addiction
ko05034	Alcoholism

Brite

KEGG Orthology (KO) [BR:ko00001]
Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
Organismal Systems
  Nervous system
   04724 Glutamatergic synapse
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   04720 Long-term potentiation
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
  Environmental adaptation
   04713 Circadian entrainment
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05014 Amyotrophic lateral sclerosis (ALS)
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05016 Huntington's disease
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
  Substance dependence
   05030 Cocaine addiction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05031 Amphetamine addiction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05033 Nicotine addiction
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
   05034 Alcoholism
    K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
Ion channels [BR:ko04040]
Glutamate-gated cation channels
  Glutamate (ionotropic), NMDA
   K05208  GRIN1; glutamate receptor ionotropic, NMDA 1

Other DBs

GO:

0004972 0005234

TC:

1.A.10.1.6 1.A.10.1.12

Genes

HSA:	2902(GRIN1)
PTR:	465176(GRIN1)
PPS:	100987673(GRIN1)
GGO:	101146203(GRIN1)
PON:	100435177(GRIN1)
MCC:	574380(GRIN1)
MMU:	14810(Grin1)
RNO:	24408(Grin1)
CFA:	494007(GRIN1)
AML:	100465687(GRIN1)
FCA:	101082021
BTA:	100336579(GRIN1)
SSC:	397440(GRIN1)
ECB:	100059861(GRIN1)
MDO:	100023485(GRIN1)
SHR:	100922600(GRIN1)
OAA:	100082705
GGA:	404296(GRIN1)
MGP:	100548054
TGU:	751779(GRIN1)
ACS:	100553024
XLA:	397953(grin1)
XTR:	780048(grin1)
DRE:	100005675(grin1b) 767745(grin1a)
TRU:	101064941
OLA:	101175170
BFO:	BRAFLDRAFT_59184 BRAFLDRAFT_82812
CIN:	100186847
DME:	Dmel_CG2902(Nmdar1)
DPO:	Dpse_GA15505
DAN:	Dana_GF17704
DER:	Dere_GG10981
DPE:	Dper_GL22160
DSE:	Dsec_GM10627
DSI:	Dsim_GD19612
DWI:	Dwil_GK23704
DYA:	Dyak_GE25274
DGR:	Dgri_GH18993
DMO:	Dmoj_GI24494
DVI:	Dvir_GJ24560
AGA:	AgaP_AGAP001478
AAG:	AaeL_AAEL008587
CQU:	CpipJ_CPIJ017065
AME:	406079(Nmdar1)
TCA:	658152
API:	100160524
PHU:	Phum_PHUM105890
ISC:	IscW_ISCW010976
CEL:	CELE_F07F6.6(nmr-1)
CBR:	CBG02401(Cbr-nmr-1)
SMM:	Smp_126350
NVE:	NEMVE_v1g171792 NEMVE_v1g198759 NEMVE_v1g211456
HMG:	100197210
NGR:	NAEGRDRAFT_46318 NAEGRDRAFT_66900

» show all

Reference

PMID:11399431

Authors

Cull-Candy S, Brickley S, Farrant M

Title

NMDA receptor subunits: diversity, development and disease.

Journal

Curr Opin Neurobiol 11:327-35 (2001)

Reference

PMID:17088105

Authors

Paoletti P, Neyton J

Title

NMDA receptor subunits: function and pharmacology.

Journal

Curr Opin Pharmacol 7:39-47 (2007)

All links

Ontology (10)   
   KEGG BRITE (6)   
   GO (2)   
   TC (2)   
Pathway (24)   
   KEGG PATHWAY (24)   
Drug (38)   
   KEGG DRUG (38)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Gene (84)   
   KEGG GENES (59)   
   KEGG DGENES (6)   
   KEGG EGENES (6)   
   KEGG MGENES (13)   
Protein sequence (40)   
   UniProt (40)   
Literature (2)   
   PubMed (2)   
All databases (200)   

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