KEGG   ORTHOLOGY: K05357Help
Entry
K05357                      KO                                     

Name
VKORC1
Definition
vitamin-K-epoxide reductase (warfarin-sensitive) [EC:1.1.4.1]
Pathway
Ubiquinone and other terpenoid-quinone biosynthesis
Disease
H00995  
Combined deficiency of vitamin K-dependent clotting factors (VKCFD)
H01205  
Coumarin resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    K05357  VKORC1; vitamin-K-epoxide reductase (warfarin-sensitive)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.4  With a disulfide as acceptor
    1.1.4.1  vitamin-K-epoxide reductase (warfarin-sensitive)
     K05357  VKORC1; vitamin-K-epoxide reductase (warfarin-sensitive)
BRITE hierarchy
Other DBs
Genes
HSA: 
79001(VKORC1)
PTR: 
100610370(VKORC1)
PPS: 
100989746(VKORC1)
GGO: 
PON: 
100434981(VKORC1)
MCC: 
MMU: 
27973(Vkorc1)
RNO: 
309004(Vkorc1)
CGE: 
100755703(Vkorc1)
HGL: 
101712530(Vkorc1)
TUP: 
102489609(VKORC1)
CFA: 
479775(VKORC1)
AML: 
FCA: 
101089669(VKORC1)
PTG: 
102964464(VKORC1)
BTA: 
445422(VKORC1)
BOM: 
102273264(VKORC1)
PHD: 
102327090(VKORC1)
CHX: 
102171296(VKORC1)
SSC: 
100522924(VKORC1)
CFR: 
102515335(VKORC1)
BACU: 
103001696(VKORC1)
LVE: 
103077074(VKORC1)
ECB: 
100063360(VKORC1)
MYB: 
MYD: 
102771765(VKORC1)
PALE: 
102886750(VKORC1)
MDO: 
100019247(VKORC1)
SHR: 
100914533(VKORC1)
OAA: 
100085063(VKORC1)
GGA: 
404205(VKORC1)
AMJ: 
MZE: 
OLA: 
XMA: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
NVI: 
BMOR: 
API: 
PHU: 
ISC: 
LOA: 
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TAD: 
TGO: 
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 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Tie JK, Jin DY, Straight DL, Stafford DW
  Title
Functional study of the vitamin K cycle in mammalian cells.
  Journal
Blood 117:2967-74 (2011)

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