KEGG   ORTHOLOGY: K05411Help
Entry
K05411                      KO                                     
Name
IRF3
Definition
interferon regulatory factor 3
Pathway
Toll-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Cytosolic DNA-sensing pathway
Pertussis
Hepatitis C
Hepatitis B
Measles
Influenza A
Herpes simplex infection
Epstein-Barr virus infection
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K05411  IRF3; interferon regulatory factor 3
   04622 RIG-I-like receptor signaling pathway
    K05411  IRF3; interferon regulatory factor 3
   04623 Cytosolic DNA-sensing pathway
    K05411  IRF3; interferon regulatory factor 3
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K05411  IRF3; interferon regulatory factor 3
  Infectious diseases
   05133 Pertussis
    K05411  IRF3; interferon regulatory factor 3
   05162 Measles
    K05411  IRF3; interferon regulatory factor 3
   05164 Influenza A
    K05411  IRF3; interferon regulatory factor 3
   05161 Hepatitis B
    K05411  IRF3; interferon regulatory factor 3
   05160 Hepatitis C
    K05411  IRF3; interferon regulatory factor 3
   05168 Herpes simplex infection
    K05411  IRF3; interferon regulatory factor 3
   05169 Epstein-Barr virus infection
    K05411  IRF3; interferon regulatory factor 3
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Helix-turn-helix
   Tryptophan clusters interferon-regulating factors
    K05411  IRF3; interferon regulatory factor 3
BRITE hierarchy
Genes
HSA: 
3661(IRF3)
PTR: 
747565(IRF3)
PPS: 
100977114(IRF3)
GGO: 
101144709(IRF3)
PON: 
100441280(IRF3)
MCC: 
718970(IRF3)
MMU: 
54131(Irf3)
RNO: 
292892(Irf3)
CFA: 
476412(IRF3)
AML: 
100471184(IRF3)
FCA: 
101095934(IRF3)
BTA: 
516979(IRF3)
SSC: 
396656(IRF3)
MDO: 
100030239
SHR: 
100933650(IRF3)
XLA: 
379275(irf3)
XTR: 
100493780
DRE: 
564854(irf3)
TRU: 
101071639
OLA: 
101158892
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8524823
  Authors
Au WC, Moore PA, Lowther W, Juang YT, Pitha PM
  Title
Identification of a member of the interferon regulatory factor family that binds  to the interferon-stimulated response element and activates expression of interferon-induced genes.
  Journal
Proc Natl Acad Sci U S A 92:11657-61 (1995)
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