KEGG   ORTHOLOGY: K05424Help
Entry
K05424                      KO                                     

Name
LEP
Definition
leptin
Pathway
Cytokine-cytokine receptor interaction
Neuroactive ligand-receptor interaction
AMPK signaling pathway
Jak-STAT signaling pathway
Adipocytokine signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05424  LEP; leptin
   04152 AMPK signaling pathway
    K05424  LEP; leptin
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05424  LEP; leptin
   04060 Cytokine-cytokine receptor interaction
    K05424  LEP; leptin
 Organismal Systems
  Endocrine system
   04920 Adipocytokine signaling pathway
    K05424  LEP; leptin
 Human Diseases
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K05424  LEP; leptin
Cytokines [BR:ko04052]
 Class I cytokines (hematopoietin family)
  IL-6 receptor family
   K05424  LEP; leptin
BRITE hierarchy
Genes
HSA: 
3952(LEP)
PTR: 
449638(LEP)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
698728(LEP)
MCF: 
CJC: 
MMU: 
16846(Lep)
RNO: 
25608(Lep)
CGE: 
NGI: 
HGL: 
OCU: 
TUP: 
CFA: 
403616(LEP)
AML: 
UMR: 
FCA: 
493838(LEP)
PTG: 
BTA: 
280836(LEP)
BOM: 
PHD: 
CHX: 
OAS: 
443534(LEP)
SSC: 
396832(LEP)
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
102242572(LEP) 102258447(Leptin)
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
TGU: 
ASN: 
AMJ: 
CMY: 
ACS: 
PBI: 
XLA: 
734226(lep)
XTR: 
DRE: 
100150233(lepa)
LCM: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Koerner A, Kratzsch J, Kiess W
  Title
Adipocytokines: leptin--the classical, resistin--the controversical, adiponectin--the promising, and more to come.
  Journal
Best Pract Res Clin Endocrinol Metab 19:525-46 (2005)

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