KEGG   ORTHOLOGY: K05426Help
Entry
K05426                      KO                                     

Name
IL23A
Definition
interleukin 23, alpha subunit p19
Pathway
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Th17 cell differentiation
Pertussis
Tuberculosis
Inflammatory bowel disease (IBD)
Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05426  IL23A; interleukin 23, alpha subunit p19
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05426  IL23A; interleukin 23, alpha subunit p19
 Organismal Systems
  Immune system
   04659 Th17 cell differentiation
    K05426  IL23A; interleukin 23, alpha subunit p19
 Human Diseases
  Immune diseases
   05323 Rheumatoid arthritis
    K05426  IL23A; interleukin 23, alpha subunit p19
   05321 Inflammatiory bowel disease (IBD)
    K05426  IL23A; interleukin 23, alpha subunit p19
  Infectious diseases
   05133 Pertussis
    K05426  IL23A; interleukin 23, alpha subunit p19
   05152 Tuberculosis
    K05426  IL23A; interleukin 23, alpha subunit p19
Cytokines [BR:ko04052]
 Class I cytokines (hematopoietin family)
  IL-6 receptor family
   K05426  IL23A; interleukin 23, alpha subunit p19
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
51561(IL23A)
PTR: 
467036(IL23A)
PPS: 
100974265(IL23A)
GGO: 
101146347(IL23A)
PON: 
100452384(IL23A)
NLE: 
100586740(IL23A)
MCC: 
712627(IL23A)
MCF: 
102128555(IL23A)
CSAB: 
103238523(IL23A)
RRO: 
104673677(IL23A)
CJC: 
100414179(IL23A)
SBQ: 
101034582(IL23A)
MMU: 
83430(Il23a)
RNO: 
155140(Il23a)
CGE: 
100765061(Il23a)
NGI: 
103746524(Il23a)
HGL: 
101707902(Il23a)
OCU: 
100352065(IL23A)
TUP: 
102477558(IL23A)
CFA: 
481110(IL23A)
AML: 
100471919(IL23A)
UMR: 
103656219(IL23A)
FCA: 
654423(IL23A)
PTG: 
102967682(IL23A)
BTA: 
511022(IL23A)
BOM: 
102277988(IL23A)
PHD: 
102318276(IL23A)
CHX: 
102190023(IL23A)
OAS: 
100462692(IL23A)
SSC: 
100155546(IL23A)
CFR: 
102511458(IL23A)
BACU: 
103000924(IL23A)
LVE: 
103081458(IL23A)
ECB: 
100034230(IL23A)
MYB: 
102240355(IL23A)
MYD: 
102765952(IL23A)
PALE: 
102879394(IL23A)
LAV: 
100656085(IL23A)
SHR: 
100933427(IL23A)
OAA: 
100087533(IL23A)
GGA: 
MGP: 
104916176(IL23A)
CJO: 
107325846(IL23A)
PHI: 
102112090(IL23A)
FPG: 
101912740(IL23A)
FCH: 
102055360(IL23A)
ASN: 
102378987(IL23A)
AMJ: 
106737722(IL23A)
ACS: 
103277778(il23a)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Duvallet E, Semerano L, Assier E, Falgarone G, Boissier MC
  Title
Interleukin-23: a key cytokine in inflammatory diseases.
  Journal
Ann Med 43:503-11 (2011)
Reference
  Authors
Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, Vega F, Yu N, Wang J, Singh K, Zonin F, Vaisberg E, Churakova T, Liu M, Gorman D, Wagner J, Zurawski S, Liu Y, Abrams JS, Moore KW, Rennick D, de Waal-Malefyt R, Hannum C, Bazan JF, Kastelein RA
  Title
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.
  Journal
Immunity 13:715-25 (2000)
  Sequence
[hsa:51561]

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