KEGG   ORTHOLOGY: K05429Help
Entry
K05429                      KO                                     

Name
IL2
Definition
interleukin 2
Pathway
Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
T cell receptor signaling pathway
Intestinal immune network for IgA production
Type I diabetes mellitus
Chagas disease (American trypanosomiasis)
Measles
HTLV-I infection
Autoimmune thyroid disease
Inflammatory bowel disease (IBD)
Allograft rejection
Graft-versus-host disease
Disease
H00084  
Graft-versus-host disease
H00408  
Type I diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05429  IL2; interleukin 2
   04151 PI3K-Akt signaling pathway
    K05429  IL2; interleukin 2
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05429  IL2; interleukin 2
 Organismal Systems
  Immune system
   04660 T cell receptor signaling pathway
    K05429  IL2; interleukin 2
   04672 Intestinal immune network for IgA production
    K05429  IL2; interleukin 2
 Human Diseases
  Immune diseases
   05320 Autoimmune thyroid disease
    K05429  IL2; interleukin 2
   05321 Inflammatiory bowel disease (IBD)
    K05429  IL2; interleukin 2
   05330 Allograft rejection
    K05429  IL2; interleukin 2
   05332 Graft-versus-host disease
    K05429  IL2; interleukin 2
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K05429  IL2; interleukin 2
  Infectious diseases
   05166 HTLV-I infection
    K05429  IL2; interleukin 2
   05162 Measles
    K05429  IL2; interleukin 2
   05142 Chagas disease (American trypanosomiasis)
    K05429  IL2; interleukin 2
Cytokines [BR:ko04052]
 Class I cytokines (hematopoietin family)
  IL-2 receptor family
   K05429  IL2; interleukin 2
Heparan sulfate/heparin binding proteins [BR:ko00536]
 Cytokines
  K05429  IL2; interleukin 2
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
3558(IL2)
PTR: 
461472(IL2)
PPS: 
GGO: 
PON: 
MCC: 
708017(IL2)
MCF: 
MMU: 
16183(Il2)
RNO: 
116562(Il2)
CGE: 
HGL: 
TUP: 
CFA: 
403989(IL2)
AML: 
FCA: 
751114(IL2)
PTG: 
BTA: 
280822(IL2)
BOM: 
PHD: 
CHX: 
SSC: 
396868(IL2)
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
GGA: 
373958(IL2)
MGP: 
FAB: 
APLA: 
101794925(IL-2)
CLV: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Liao W, Lin JX, Leonard WJ
  Title
IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation.
  Journal
Curr Opin Immunol 23:598-604 (2011)

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