KEGG   ORTHOLOGY: K05429
Entry
K05429                      KO                                     
Symbol
IL2
Name
interleukin 2
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04151  PI3K-Akt signaling pathway
map04625  C-type lectin receptor signaling pathway
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map04672  Intestinal immune network for IgA production
map04940  Type I diabetes mellitus
map05135  Yersinia infection
map05142  Chagas disease
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05320  Autoimmune thyroid disease
map05321  Inflammatory bowel disease
map05330  Allograft rejection
map05332  Graft-versus-host disease
Disease
H00084  Graft-versus-host disease
H00408  Type 1 diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05429  IL2; interleukin 2
   04151 PI3K-Akt signaling pathway
    K05429  IL2; interleukin 2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05429  IL2; interleukin 2
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05429  IL2; interleukin 2
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K05429  IL2; interleukin 2
   04660 T cell receptor signaling pathway
    K05429  IL2; interleukin 2
   04658 Th1 and Th2 cell differentiation
    K05429  IL2; interleukin 2
   04659 Th17 cell differentiation
    K05429  IL2; interleukin 2
   04672 Intestinal immune network for IgA production
    K05429  IL2; interleukin 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05429  IL2; interleukin 2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05429  IL2; interleukin 2
   05171 Coronavirus disease - COVID-19
    K05429  IL2; interleukin 2
   05162 Measles
    K05429  IL2; interleukin 2
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K05429  IL2; interleukin 2
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K05429  IL2; interleukin 2
  09163 Immune disease
   05320 Autoimmune thyroid disease
    K05429  IL2; interleukin 2
   05321 Inflammatory bowel disease
    K05429  IL2; interleukin 2
   05330 Allograft rejection
    K05429  IL2; interleukin 2
   05332 Graft-versus-host disease
    K05429  IL2; interleukin 2
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    K05429  IL2; interleukin 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05429  IL2; interleukin 2
   00536 Glycosaminoglycan binding proteins
    K05429  IL2; interleukin 2
Cytokines and neuropeptides [BR:ko04052]
 Cytokines
  Interleukins
   K05429  IL2; interleukin 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Cytokines
   K05429  IL2; interleukin 2
Other DBs
GO: 0005134
Genes
HSA: 3558(IL2)
PTR: 461472(IL2)
PPS: 100984780(IL2)
GGO: 101132394(IL2)
PON: 100455248(IL2)
NLE: 100591126(IL2)
HMH: 116479944(IL2)
MCC: 708017(IL2)
MCF: 102129830(IL2)
MTHB: 126955754
MNI: 105486135(IL2)
CSAB: 103236209(IL2)
CATY: 105595801(IL2)
PANU: 100126754(IL2)
TGE: 112624904(IL2)
MLEU: 105538406(IL2)
RRO: 104661748(IL2)
RBB: 108515581(IL2)
TFN: 117084792(IL2)
PTEH: 111546287(IL2)
CANG: 105516414(IL2)
CJC: 100386848(IL2)
SBQ: 101028427(IL2)
CIMI: 108297648(IL2)
CSYR: 103270878(IL2)
MMUR: 105882081(IL2)
LCAT: 123637712(IL2)
PCOQ: 105815260(IL2)
OGA: 100942002(IL2)
MMU: 16183(Il2)
MCAL: 110291180(Il2)
MPAH: 110320556(Il2)
RNO: 116562(Il2)
MCOC: 116094798(Il2)
ANU: 117707066(Il2)
MUN: 110545874(Il2) 110560079
CGE: 100755773(Il2)
MAUA: 101835410(Il2)
PROB: 127223186(Il2)
PLEU: 114707177(Il2)
MORG: 121452714(Il2)
MFOT: 126499332
AAMP: 119825919(Il2)
NGI: 103746951(Il2)
HGL: 101720581(Il2)
CPOC: 100379540(Il2)
CCAN: 109691916(Il2)
DORD: 105989886(Il2)
DSP: 122119081(Il2)
PLOP: 125341318(Il2)
NCAR: 124994815
MMMA: 107136571(Il2)
OCU: 100302458(IL2)
OPI: 101519556(IL2)
TUP: 102478615(IL2)
GVR: 103593609(IL2)
CFA: 403989(IL2)
CLUD: 112642744(IL2)
VVP: 112933619(IL2)
VLG: 121492803(IL2)
NPO: 129504325(IL2)
AML: 100480862(IL2)
UMR: 103661804(IL2)
UAH: 113255635(IL2)
UAR: 123793114(IL2)
ELK: 111154869
LLV: 125093350
MPUF: 101674110(IL2)
MNP: 132014406(IL2)
MLK: 131828386(IL2)
NVS: 122890130(IL2)
ORO: 101386196(IL2)
EJU: 114208234(IL2)
ZCA: 113925933(IL2)
MLX: 118022354(IL2)
NSU: 110573034(IL2)
LWW: 102742200(IL2)
FCA: 751114(IL2)
PYU: 121030128(IL2)
PCOO: 112858002(IL2)
PBG: 122476434(IL2)
PVIV: 125164688(IL2)
LRUF: 124520662
PTG: 102957506(IL2)
PPAD: 109248906(IL2)
PUC: 125923086
AJU: 106977102
HHV: 120238026(IL2)
BTA: 280822(IL2)
BOM: 102272426(IL2)
BIU: 109571028(IL2)
BBUB: 102395421(IL2)
BBIS: 105003236(IL2)
CHX: 102183089(IL2)
OAS: 443401(IL2)
BTAX: 128062529(IL2)
ODA: 120870984(IL2)
CCAD: 122453281(IL2)
MBEZ: 129542297(IL2)
SSC: 396868(IL2)
CFR: 102514894(IL2)
CBAI: 105067115(IL2)
CDK: 105093664(IL2)
VPC: 102532988(IL2)
BACU: 103017896(IL2)
BMUS: 118895628(IL2)
LVE: 103071508(IL2)
OOR: 101274648(IL2)
DLE: 111186150(IL2)
PCAD: 102990654(IL2)
PSIU: 116754231(IL2)
NASI: 112399755(IL2)
ECB: 100034204(IL2)
EPZ: 103557874(IL2)
EAI: 106834088(IL2)
MYB: 102246940(IL2)
MYD: 102773629(IL2)
MMYO: 118658725(IL2)
MLF: 102433200(IL2)
PKL: 118711847(IL2)
EFUS: 103287584(IL2)
MNA: 107529760(IL2)
DRO: 112312503(IL2)
SHON: 118995277(IL2)
AJM: 119037638(IL2)
PDIC: 114502552(IL2)
PHAS: 123814106(IL2)
MMF: 118643998(IL2)
PPAM: 129061444(IL2)
HAI: 109395924(IL2)
RFQ: 117038186(IL2)
PALE: 102895516(IL2)
PGIG: 120616276(IL2)
PVP: 105302208(IL2)
RAY: 107505383(IL2)
MJV: 108383567(IL2)
TOD: 119233628(IL2)
SARA: 101556429(IL2)
SETR: 126004457(IL2)
LAV: 100656398(IL2)
TMU: 101360180
ETF: 101658181(IL2)
DNM: 101413757(IL2)
MDO: 100619184(IL2)
GAS: 123251137(IL2)
SHR: 100935068
AFZ: 127541142
PCW: 110223001
GGA: 373958(IL2)
PCOC: 116231224
MGP: 100303688
LMUT: 125692515
APLA: 101794925(IL-2)
ACYG: 125184558
FAB: 101807567(IL2)
CBRC: 103617467
CLV: 102091580
TALA: 104359387
AFOR: 103907343
HALD: 104317093
HLE: 104836857
AGEN: 126045031
CCRI: 104157355
GSTE: 104256903
PGUU: 104460515
TEO: 104375916
ASAO: 132776874
 » show all
Reference
PMID:6312994
  Authors
Maeda S, Nishino N, Obaru K, Mita S, Nomiyama H, Shimada K, Fujimoto K, Teranishi T, Hirano T, Onoue K
  Title
Cloning of interleukin 2 mRNAs from human tonsils.
  Journal
Biochem Biophys Res Commun 115:1040-7 (1983)
DOI:10.1016/S0006-291X(83)80040-0
  Sequence
[hsa:3558]

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Ontology (4)   
   KEGG BRITE (3)   
   GO (1)   
Pathway (40)   
   KEGG PATHWAY (40)   
Disease (2)   
   KEGG DISEASE (2)   
Drug (3)   
   KEGG DRUG (3)   
Gene (169)   
   KEGG GENES (167)   
   OC (2)   
Literature (1)   
   PubMed (1)   
All databases (219)   

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