KEGG   ORTHOLOGY: K05448Help
Entry
K05448                      KO                                     

Name
VEGFA
Definition
vascular endothelial growth factor A
Pathway
EGFR tyrosine kinase inhibitor resistance
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
HIF-1 signaling pathway
PI3K-Akt signaling pathway
VEGF signaling pathway
Focal adhesion
AGE-RAGE signaling pathway in diabetic complications
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Pancreatic cancer
Bladder cancer
Rheumatoid arthritis
Disease
H00018  
Gastric cancer
H01456  
Diabetic nephropathy
H01457  
Diabetic retinopathy
H01459  
Diabetic neuropathy
H01529  
Avascular necrosis of femoral head
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05448  VEGFA; vascular endothelial growth factor A
   04015 Rap1 signaling pathway
    K05448  VEGFA; vascular endothelial growth factor A
   04370 VEGF signaling pathway
    K05448  VEGFA; vascular endothelial growth factor A
   04066 HIF-1 signaling pathway
    K05448  VEGFA; vascular endothelial growth factor A
   04151 PI3K-Akt signaling pathway
    K05448  VEGFA; vascular endothelial growth factor A
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05448  VEGFA; vascular endothelial growth factor A
 Cellular Processes
  Cellular commiunity
   04510 Focal adhesion
    K05448  VEGFA; vascular endothelial growth factor A
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05448  VEGFA; vascular endothelial growth factor A
   05206 MicroRNAs in cancer
    K05448  VEGFA; vascular endothelial growth factor A
   05205 Proteoglycans in cancer
    K05448  VEGFA; vascular endothelial growth factor A
   05212 Pancreatic cancer
    K05448  VEGFA; vascular endothelial growth factor A
   05211 Renal cell carcinoma
    K05448  VEGFA; vascular endothelial growth factor A
   05219 Bladder cancer
    K05448  VEGFA; vascular endothelial growth factor A
  Immune diseases
   05323 Rheumatoid arthritis
    K05448  VEGFA; vascular endothelial growth factor A
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    K05448  VEGFA; vascular endothelial growth factor A
  Antineoplastic resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    K05448  VEGFA; vascular endothelial growth factor A
Cytokines [BR:ko04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass I
    K05448  VEGFA; vascular endothelial growth factor A
Cell adhesion molecules and their ligands [BR:ko04516]
 7. Others
  NRP1; neuropilin 1
   K05448 VEGFA; vascular endothelial growth factor A
  NRP2; neuropilin 2
   K05448 VEGFA; vascular endothelial growth factor A
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Growth factors/receptors
   K05448  VEGFA; vascular endothelial growth factor A
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
7422(VEGFA)
PTR: 
PPS: 
100970217(VEGFA)
GGO: 
101131949(VEGFA)
PON: 
100448769(VEGFA)
NLE: 
MCC: 
574209(VEGFA)
MCF: 
102140241(VEGFA)
RRO: 
104667362(VEGFA)
CJC: 
100389629(VEGFA)
MMU: 
22339(Vegfa)
RNO: 
83785(Vegfa)
CGE: 
100755957(Vegfa)
NGI: 
103730772(Vegfa)
HGL: 
101702403(Vegfa)
OCU: 
100008899(VEGFA)
TUP: 
102499303(VEGFA)
CFA: 
403802(VEGFA)
AML: 
100482983(VEGFA)
UMR: 
103664148(VEGFA)
FCA: 
493845(VEGFA)
PTG: 
102954556(VEGFA)
BTA: 
281572(VEGFA)
BOM: 
102270607(VEGFA)
PHD: 
102319777(VEGFA)
CHX: 
100860957(VEGFA)
OAS: 
443103(VEGFA)
SSC: 
397157(VEGFA)
CFR: 
102514843(VEGFA)
BACU: 
103008131(VEGFA)
LVE: 
103089095(VEGFA)
ECB: 
100033839(VEGFA)
MYB: 
102254357(VEGFA)
MYD: 
102771975(VEGFA)
PALE: 
102890394(VEGFA)
MDO: 
100012132(VEGFA)
SHR: 
100913423(VEGFA)
OAA: 
GGA: 
395909(VEGFA)
MGP: 
100539186(VEGFA)
CJO: 
107311307(VEGFA)
APLA: 
101805258(VEGFA)
TGU: 
100230266(VEGFA)
GFR: 
102038819(VEGFA)
FAB: 
101806742(VEGFA)
PHI: 
102114381(VEGFA)
CCW: 
104684484(VEGFA)
FPG: 
101913384(VEGFA)
FCH: 
102053577(VEGFA)
CLV: 
102087578(VEGFA)
AAM: 
106485436(VEGFA)
ASN: 
102372950(VEGFA)
AMJ: 
102576555(VEGFA)
PSS: 
102448827(VEGFB) 102456411(VEGFA)
CMY: 
ACS: 
100568086(vegfa)
PBI: 
103060055(VEGFA) 103062159(VEGFB)
GJA: 
107125774(VEGFA)
XLA: 
100037058(vegfa-b) 373589(vegfa-a)
XTR: 
100038089(vegfa)
DRE: 
30682(vegfaa) 558154(vegfab)
TRU: 
MZE: 
101467969(vegfb) 101472090(vegfa)
OLA: 
100125510(vegfa)
XMA: 
102234868(vegfa)
LCM: 
102347582(VEGFB) 102367264(VEGFA)
CMK: 
103179198(vegfa)
VG: 
25479060(AMQ81_gp011) 2947897(BPSVgORF006) 8797204(PCPV_gp003) 8797333(PCPV_gp132)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
PMID:2479986
  Authors
Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N
  Title
Vascular endothelial growth factor is a secreted angiogenic mitogen.
  Journal
Science 246:1306-9 (1989)
  Sequence
[hsa:7422]

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