KEGG   ORTHOLOGY: K05450Help
Entry
K05450                      KO                                     

Name
PDGFC_D
Definition
platelet derived growth factor C/D
Pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Regulation of actin cytoskeleton
Prostate cancer
Melanoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05450  PDGFC_D; platelet derived growth factor C/D
   04015 Rap1 signaling pathway
    K05450  PDGFC_D; platelet derived growth factor C/D
   04151 PI3K-Akt signaling pathway
    K05450  PDGFC_D; platelet derived growth factor C/D
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05450  PDGFC_D; platelet derived growth factor C/D
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05450  PDGFC_D; platelet derived growth factor C/D
  Cellular commiunity
   04510 Focal adhesion
    K05450  PDGFC_D; platelet derived growth factor C/D
   04540 Gap junction
    K05450  PDGFC_D; platelet derived growth factor C/D
 Human Diseases
  Cancers
   05218 Melanoma
    K05450  PDGFC_D; platelet derived growth factor C/D
   05215 Prostate cancer
    K05450  PDGFC_D; platelet derived growth factor C/D
Cytokines [BR:ko04052]
 PDGF family
  Cysteine-knot growth factors
   Subclass I
    K05450  PDGFC_D; platelet derived growth factor C/D
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    PDGFRA; platelet-derived growth factor receptor, alpha polypeptide
     K05450 PDGFC_D; platelet derived growth factor C/D
    PDGFRB; platelet-derived growth factor receptor, beta polypeptide
     K05450 PDGFC_D; platelet derived growth factor C/D
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
56034(PDGFC) 80310(PDGFD)
PTR: 
466765(PDGFD) 736477(PDGFC)
PPS: 
100982459(PDGFC) 100992738(PDGFD)
GGO: 
101134877(PDGFD) 101144807(PDGFC)
PON: 
100172718(PDGFD) 100437861(PDGFC)
MCC: 
700236(PDGFC) 704310(PDGFD)
MCF: 
MMU: 
54635(Pdgfc) 71785(Pdgfd)
RNO: 
66018(Pdgfd) 79429(Pdgfc)
CGE: 
100756952(Pdgfd) 100765334(Pdgfc)
HGL: 
101696768(Pdgfd) 101710927(Pdgfc)
TUP: 
102485007(PDGFD) 102487522(PDGFC)
CFA: 
479460(PDGFD) 482666(PDGFC)
AML: 
FCA: 
101084984(PDGFD) 101088742(PDGFC)
PTG: 
102949957(PDGFD) 102970530(PDGFC)
BTA: 
525931(PDGFD) 613787(PDGFC)
BOM: 
102273267(PDGFD) 102274384(PDGFC)
PHD: 
102331529(PDGFC) 102341549(PDGFD)
CHX: 
102168651(PDGFD) 102168934(PDGFC)
OAS: 
101112600(PDGFC) 101117784(PDGFD)
SSC: 
100515267(PDGFC) 100524161(PDGFD)
CFR: 
102508964(PDGFC) 102515439(PDGFD)
BACU: 
103015925(PDGFD) 103019677(PDGFC)
LVE: 
103076387(PDGFC) 103085046(PDGFD)
ECB: 
100061488(PDGFD) 100062015(PDGFC)
MYB: 
102240259(PDGFD) 102248385(PDGFC)
MYD: 
102766117(PDGFC) 102772727(PDGFD)
PALE: 
102890668(PDGFC) 102894123(PDGFD)
MDO: 
100011261(PDGFD) 100023701(PDGFC)
SHR: 
100916102(PDGFD) 100928148(PDGFC)
OAA: 
100078558(PDGFD) 100079757(PDGFC)
GGA: 
395469(PDGFC) 418978(PDGFD)
MGP: 
APLA: 
101789650(PDGFC) 101798843(PDGFD)
TGU: 
100217775(PDGFC) 100221512(PDGFD)
FAB: 
101806397(PDGFD) 101808607(PDGFC)
PHI: 
102106969(PDGFC) 102112153(PDGFD)
FPG: 
101910328(PDGFD) 101915028(PDGFC)
FCH: 
102048020(PDGFC) 102052290(PDGFD)
CLV: 
102087107(PDGFC) 102088608(PDGFD)
ASN: 
102378690(PDGFC) 102380973(PDGFD)
AMJ: 
PSS: 
102445898(PDGFD) 102452310(PDGFC)
CMY: 
102930493(PDGFD) 102939099(PDGFC)
ACS: 
100551866(pdgfd) 100568114(pdgfc)
PBI: 
XTR: 
DRE: 
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102351685(PDGFD) 102356509(PDGFC)
CMK: 
103182267(pdgfc) 103185765(pdgfd)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Fredriksson L, Li H, Eriksson U
  Title
The PDGF family: four gene products form five dimeric isoforms.
  Journal
Cytokine Growth Factor Rev 15:197-204 (2004)

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