KEGG   ORTHOLOGY: K05459Help
Entry
K05459                      KO                                     
Name
IGF1
Definition
insulin-like growth factor 1
Pathway
HIF-1 signaling pathway
Oocyte meiosis
p53 signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
Focal adhesion
Long-term depression
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Aldosterone-regulated sodium reabsorption
Pathways in cancer
Transcriptional misregulation in cancer
Proteoglycans in cancer
Glioma
Prostate cancer
Melanoma
Hypertrophic cardiomyopathy (HCM)
Dilated cardiomyopathy
Disease
H00015  
Malignant pleural mesothelioma
H00254  
Pituitary Dwarfism (PD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    K05459  IGF1; insulin-like growth factor 1
   04151 PI3K-Akt signaling pathway
    K05459  IGF1; insulin-like growth factor 1
   04150 mTOR signaling pathway
    K05459  IGF1; insulin-like growth factor 1
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K05459  IGF1; insulin-like growth factor 1
   04115 p53 signaling pathway
    K05459  IGF1; insulin-like growth factor 1
  Cell communication
   04510 Focal adhesion
    K05459  IGF1; insulin-like growth factor 1
 Organismal Systems
  Endocrine system
   04913 Ovarian Steroidogenesis
    K05459  IGF1; insulin-like growth factor 1
   04914 Progesterone-mediated oocyte maturation
    K05459  IGF1; insulin-like growth factor 1
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K05459  IGF1; insulin-like growth factor 1
  Nervous system
   04730 Long-term depression
    K05459  IGF1; insulin-like growth factor 1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05459  IGF1; insulin-like growth factor 1
   05202 Transcriptional misregulation in cancers
    K05459  IGF1; insulin-like growth factor 1
   05205 Proteoglycans in cancer
    K05459  IGF1; insulin-like growth factor 1
   05214 Glioma
    K05459  IGF1; insulin-like growth factor 1
   05218 Melanoma
    K05459  IGF1; insulin-like growth factor 1
   05215 Prostate cancer
    K05459  IGF1; insulin-like growth factor 1
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K05459  IGF1; insulin-like growth factor 1
   05414 Dilated cardiomyopathy (DCM)
    K05459  IGF1; insulin-like growth factor 1
Cytokines [BR:ko04052]
 PDGF family
  Other growth factors
   K05459  IGF1; insulin-like growth factor 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
3479(IGF1)
PTR: 
741055(IGF1)
PPS: 
100982978(IGF1)
GGO: 
101154397(IGF1)
PON: 
100444645(IGF1)
MCC: 
698444(IGF1)
MMU: 
16000(Igf1)
RNO: 
24482(Igf1)
CFA: 
610255(IGF1)
AML: 
100473254(IGF1)
FCA: 
101101237(IGF1)
BTA: 
281239(IGF1)
SSC: 
397491(IGF1)
ECB: 
100034198(IGF1)
MDO: 
100021295
SHR: 
100918816(IGF1)
OAA: 
100075905
GGA: 
418090(IGF1)
MGP: 
678666(IGF1)
TGU: 
100226283(IGF1)
ACS: 
100566682
XLA: 
378699(igf1)
XTR: 
100486334
DRE: 
114433(igf1)
TRU: 
100462939(igf-1)
OLA: 
101168167
DGR: 
Dgri_GH24248
DVI: 
Dvir_GJ16462
SMM: 
Smp_151640
NVE: 
NEMVE_v1g207484
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Furstenberger G, Senn HJ
  Title
Insulin-like growth factors and cancer.
  Journal
Lancet Oncol 3:298-302 (2002)
DBGET integrated database retrieval system