KEGG   ORTHOLOGY: K05473Help
Entry
K05473                      KO                                     

Name
TNFSF11, RANKL, CD254
Definition
tumor necrosis factor ligand superfamily member 11
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04064  NF-kappa B signaling pathway
ko04380  Osteoclast differentiation
ko04917  Prolactin signaling pathway
ko04928  Parathyroid hormone synthesis, secretion and action
ko05224  Breast cancer
ko05323  Rheumatoid arthritis
Disease
H00436  Osteopetrosis
H01470  Giant cell tumor of bone
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
 Organismal Systems
  Endocrine system
   04917 Prolactin signaling pathway
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
   04928 Parathyroid hormone synthesis, secretion and action
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  Development
   04380 Osteoclast differentiation
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
 Human Diseases
  Cancers
   05224 Breast cancer
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  Immune diseases
   05323 Rheumatoid arthritis
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Tumor necrosis fators
   K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
CD molecules [BR:ko04090]
 Proteins
  K05473  CD254, TNFSF11; tumor necrosis factor (ligand) superfamily, member 11
BRITE hierarchy
Other DBs
GO: 0005164
Genes
HSA: 8600(TNFSF11)
PTR: 467353(TNFSF11)
PPS: 100994539(TNFSF11)
GGO: 101131644(TNFSF11)
PON: 100439883(TNFSF11)
NLE: 100599838(TNFSF11)
MCC: 699955(TNFSF11)
MCF: 102137946(TNFSF11)
CSAB: 103214344(TNFSF11)
RRO: 104671084(TNFSF11)
RBB: 108514105(TNFSF11)
CJC: 100401379(TNFSF11)
SBQ: 101051208(TNFSF11)
MMU: 21943(Tnfsf11)
RNO: 103689974 117516(Tnfsf11)
CGE: 100768715(Tnfsf11)
NGI: 103751291(Tnfsf11)
HGL: 101696350(Tnfsf11)
CCAN: 109700348(Tnfsf11)
OCU: 100341009(TNFSF11)
TUP: 102487682(TNFSF11)
CFA: 609418(TNFSF11)
AML: 100483079(TNFSF11)
UMR: 103677566(TNFSF11)
ORO: 101376926(TNFSF11)
FCA: 724036(TNFSF11)
PTG: 102954463(TNFSF11)
AJU: 106971982(TNFSF11)
BTA: 513836(TNFSF11)
BOM: 102267691(TNFSF11)
BIU: 109566677(TNFSF11)
PHD: 102322277(TNFSF11)
CHX: 102176335(TNFSF11)
OAS: 100037694(TNFSF11)
SSC: 100037976(TNFSF11)
CFR: 102507742(TNFSF11)
CDK: 105089768(TNFSF11)
BACU: 103002678(TNFSF11)
LVE: 103074658(TNFSF11)
OOR: 101284929(TNFSF11)
ECB: 100060254(TNFSF11)
EPZ: 103560371(TNFSF11)
EAI: 106847554(TNFSF11)
MYB: 102260756(TNFSF11)
MYD: 102751742(TNFSF11) 102770689
HAI: 109386844(TNFSF11)
RSS: 109457123(TNFSF11)
PALE: 102896284(TNFSF11)
LAV: 100663523(TNFSF11)
TMU: 101342165
MDO: 100011641(TNFSF11)
SHR: 100919417 105750026(TNFSF11)
OAA: 100076541(TNFSF11)
GGA: 428067(TNFSF11)
MGP: 104917524(TNFSF11)
CJO: 107308113(TNFSF11)
APLA: 101803149(TNFSF11)
ACYG: 106035087(TNFSF11)
TGU: 100227247(TNFSF11)
GFR: 102038556(TNFSF11)
FAB: 101822088(TNFSF11)
PHI: 102111124(TNFSF11)
PMAJ: 107212828(TNFSF11)
CCW: 104693175(TNFSF11)
FPG: 101919009(TNFSF11)
FCH: 102050665(TNFSF11)
CLV: 102098042(TNFSF11)
EGZ: 104132030(TNFSF11)
AAM: 106489200(TNFSF11)
ASN: 102387902(TNFSF11)
AMJ: 102559854(TNFSF11)
PSS: 102444457(TNFSF11)
CMY: 102947527(TNFSF11)
CPIC: 101936501(TNFSF11)
ACS: 100566737(tnfsf11)
PVT: 110084678(TNFSF11)
PBI: 103049538(TNFSF11)
GJA: 107123862(TNFSF11)
XLA: 496322(tnfsf11.L) 733333(tnfsf11.S)
XTR: 100038074(tnfsf11)
NPR: 108790250(TNFSF11)
SRX: 107713713 107749039(tnfsf11)
SANH: 107661329(tnfsf11) 107688674
TRU: 101080086(tnfsf11)
LCO: 104934832
NCC: 104965038(tnfsf11)
MZE: 101482899(tnfsf11)
XMA: 102231551(tnfsf11)
PRET: 103481812(tnfsf11)
NFU: 107389518(tnfsf11)
CSEM: 103391567(tnfsf11)
HCQ: 109514543(tnfsf11)
BPEC: 110170617(tnfsf11)
SFM: 108920497(tnfsf11) 108928984
LCM: 102363811(TNFSF11)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9367155
  Authors
Anderson DM, Maraskovsky E, Billingsley WL, Dougall WC, Tometsko ME, Roux ER, Teepe MC, DuBose RF, Cosman D, Galibert L
  Title
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.
  Journal
Nature 390:175-9 (1997)
DOI:10.1038/36593
  Sequence
[hsa:8600]

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