KEGG   ORTHOLOGY: K05689Help
Entry
K05689                      KO                                     

Name
CDH1, CDHE, CD324
Definition
cadherin 1, type 1, E-cadherin
Pathway
Rap1 signaling pathway
Hippo signaling pathway
Cell adhesion molecules (CAMs)
Adherens junction
Bacterial invasion of epithelial cells
Pathogenic Escherichia coli infection
Pathways in cancer
Endometrial cancer
Thyroid cancer
Melanoma
Bladder cancer
Disease
H00018  
Gastric cancer
H00025  
Penile cancer
H00031  
Breast cancer
H00032  
Thyroid cancer
H00048  
Hepatocellular carcinoma
H00054  
Nasopharyngeal cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   04390 Hippo signaling pathway
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
  Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   05216 Thyroid cancer
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   05218 Melanoma
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   05219 Bladder cancer
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   05213 Endometrial cancer
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
  Infectious diseases
   05130 Pathogenic Escherichia coli infection
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   05100 Bacterial invasion of epithelial cells
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
Chromosome [BR:ko03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Other centriole associated proteins
    K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
Cell adhesion molecules and their ligands [BR:ko04516]
 2. Integrin Family
  Beta1 integrins
   VLA-2
    ITGB1; integrin beta 1
     K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
  Beta7 integrins
   alpha E beta 7
    ITGB7; integrin beta 7
     K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
 5. Cadherin Family
  Classic Cadherins
   Vertebrate Type I classic cadherins
    CDHE, CDH1; cadherin 1, type 1, E-cadherin
     K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
   Other classic cadherins
    CDH17; cadherin 17, LI cadherin
     K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
Cellular antigens [BR:ko04090]
 Proteins
  K05689  CD324, CDH1; cadherin 1, type 1, E-cadherin (epithelial)
BRITE hierarchy
Genes
HSA: 
999(CDH1)
PTR: 
468009(CDH1)
PPS: 
100989112(CDH1)
GGO: 
101145191(CDH1)
PON: 
100174439(CDH1)
NLE: 
100596627(CDH1)
MCC: 
704387(CDH1)
MCF: 
102143513(CDH1)
CSAB: 
103233229(CDH1)
RRO: 
104655589(CDH1)
CJC: 
100398679(CDH1)
SBQ: 
101049706(CDH1)
MMU: 
12550(Cdh1)
RNO: 
83502(Cdh1)
CGE: 
100758185(Cdh1)
NGI: 
103734864(Cdh1)
HGL: 
101719565(Cdh1)
OCU: 
100356548(CDH1)
TUP: 
102499381(CDH1)
CFA: 
AML: 
100475573(CDH1)
UMR: 
FCA: 
PTG: 
BTA: 
282637(CDH1)
BOM: 
102284702(CDH1)
PHD: 
102326227(CDH1)
CHX: 
102170451(CDH1)
OAS: 
101119747(CDH1)
SSC: 
100048953(CDH1)
CFR: 
102518832(CDH1)
BACU: 
102999370(CDH1)
LVE: 
103073913(CDH1)
ECB: 
100066844(CDH1)
MYB: 
MYD: 
PALE: 
102886394(CDH1)
LAV: 
MDO: 
100027800(CDH1)
SHR: 
100920258(CDH1)
OAA: 
100079609(CDH1)
GGA: 
415860(CDH1)
MGP: 
CJO: 
APLA: 
TGU: 
100232461(CDH1)
GFR: 
102040110(CDH1)
FAB: 
101805985(CDH1)
PHI: 
CCW: 
104691942(CDH1)
FCH: 
CLV: 
AAM: 
ASN: 
102380182(CDH1)
AMJ: 
PSS: 
CMY: 
102948095 102948317(B-cadherin)
ACS: 
PBI: 
GJA: 
XLA: 
100337618(cdh1.S) 394290(cdh3.S) 594865(cdh3.L)
XTR: 
DRE: 
114424(cdh1)
TRU: 
TNG: 
MZE: 
OLA: 
XMA: 
SASA: 
LCM: 
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8459805
  Authors
Bussemakers MJ, van Bokhoven A, Mees SG, Kemler R, Schalken JA
  Title
Molecular cloning and characterization of the human E-cadherin cDNA.
  Journal
Mol Biol Rep 17:123-8 (1993)
  Sequence
[hsa:999]
Reference
  Authors
Agiostratidou G, Muros RM, Shioi J, Marambaud P, Robakis NK
  Title
The cytoplasmic sequence of E-cadherin promotes non-amyloidogenic degradation of  A beta precursors.
  Journal
J Neurochem 96:1182-8 (2006)

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