KEGG   ORTHOLOGY: K05700Help
Entry
K05700                      KO                                     

Name
VCL
Definition
vinculin
Pathway
ko04510  Focal adhesion
ko04520  Adherens junction
ko04670  Leukocyte transendothelial migration
ko04810  Regulation of actin cytoskeleton
ko05100  Bacterial invasion of epithelial cells
ko05131  Shigellosis
ko05146  Amoebiasis
Disease
H00292  Hypertrophic cardiomyopathy (HCM)
H00294  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K05700  VCL; vinculin
   04520 Adherens junction
    K05700  VCL; vinculin
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05700  VCL; vinculin
 Organismal Systems
  Immune system
   04670 Leukocyte transendothelial migration
    K05700  VCL; vinculin
 Human Diseases
  Infectious diseases
   05131 Shigellosis
    K05700  VCL; vinculin
   05100 Bacterial invasion of epithelial cells
    K05700  VCL; vinculin
   05146 Amoebiasis
    K05700  VCL; vinculin
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     K05700  VCL; vinculin
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K05700  VCL; vinculin
BRITE hierarchy
Genes
HSA: 7414(VCL)
PTR: 450531(VCL)
PPS: 100985400(VCL)
GGO: 101139107(VCL)
PON: 100432920(VCL)
NLE: 100583187(VCL) 105739011
MCC: 721921(VCL)
MCF: 102121587(VCL) 102146796
CSAB: 103215981(VCL)
RRO: 104669976(VCL)
RBB: 108516871(VCL) 108529374
CJC: 100410985(VCL)
SBQ: 101045429(VCL)
MMU: 22330(Vcl)
RNO: 305679(Vcl)
CGE: 100759958(Vcl)
NGI: 103747454(Vcl)
HGL: 101718198(Vcl)
TUP: 102470450(VCL)
CFA: 479252(VCL)
AML: 100476722(VCL)
UMR: 103667838(VCL)
ORO: 101370048(VCL)
FCA: 101089215(VCL)
PTG: 102955770(VCL)
AJU: 106970987(VCL)
BTA: 783645(VCL)
BOM: 102277897
BIU: 109553704(VCL)
PHD: 102323702(VCL)
CHX: 102188740(VCL)
OAS: 101121312(VCL)
SSC: 396974(VCL)
CFR: 102522415(VCL)
CDK: 105092450(VCL) 105106796
BACU: 103005110(VCL)
LVE: 103091613(VCL)
OOR: 101280840(VCL)
ECB: 100064165(VCL)
EPZ: 103549474(VCL)
EAI: 106843547(VCL)
MYB: 102248413(VCL)
MYD: 102757506(VCL)
HAI: 109372637(VCL)
RSS: 109454844(VCL)
PALE: 102879421(VCL)
LAV: 100654211(VCL)
TMU: 101350153
MDO: 100010978(VCL)
SHR: 100918576(VCL)
OAA: 100075715(VCL)
GGA: 396422(VCL)
MGP: 100302597(VCL)
CJO: 107315809(VCL)
APLA: 101801443(VCL)
ACYG: 106033076(VCL)
TGU: 100228062(VCL)
GFR: 102037591(VCL)
FAB: 101812247(VCL)
PHI: 102104148(VCL)
PMAJ: 107206746(VCL)
CCW: 104697492(VCL)
FPG: 101915718(VCL)
FCH: 102057999(VCL)
CLV: 102096474(VCL)
EGZ: 104129009(VCL)
AAM: 106498898(VCL)
ASN: 102378257(VCL)
AMJ: 102569963(VCL)
PSS: 102456647(VCL)
CMY: 102933251(VCL)
CPIC: 101947039(VCL)
ACS: 100564007(vcl)
PVT: 110077797(VCL)
PBI: 103065712(VCL)
GJA: 107113229(VCL)
XLA: 373770(vcl.S)
XTR: 100036705(vcl)
NPR: 108797655(VCL)
DRE: 552980(vcla)
IPU: 108263186(vcl) 108273866
TRU: 101066406(vcl) 101071113
LCO: 104931687(vcl) 104939608(Vinculin) 109139843
OLA: 101170227(vcl) 101172101
XMA: 102222474 102228164(vcl)
PRET: 103476978 103481817(vcl)
NFU: 107375598 107387561(vcl)
HCQ: 109513384(vcl) 109516252
ELS: 105010680 105027398(vcl)
CMK: 103181903(vcl)
CIN: 100185663
SPU: 590672
APLC: 110981194
SKO: 100371677
DME: Dmel_CG3299(Vinc)
DSI: Dsimw501_GD27324(Dsim_GD27324)
MDE: 101895839
AAG: 5567126
AME: 552082(Vinc)
BIM: 100744506
BTER: 100649713
AEC: 105149001
ACEP: 105622093
HST: 105186425
CFO: 105250832
LHU: 105679742
PGC: 109857525
NVI: 100124100
TCA: 659554
DPA: 109537106
NVL: 108566128
BMOR: 101736001
PMAC: 106711285
PRAP: 110991767
API: 100167107
DNX: 107163083
ZNE: 110835998
FCD: 110862559
TUT: 107361290
CEL: CELE_ZC477.9(deb-1)
CBR: CBG05763(Cbr-deb-1)
BMY: Bm1_37935
TSP: Tsp_10988
CRG: 105327367
MYI: 110462068
OBI: 106880561
SHX: MS3_08642
HMG: 100199247
AQU: 100634503
DDI: DDB_G0285939(vinA)
DFA: DFA_00762(vinA)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Le Clainche C, Dwivedi SP, Didry D, Carlier MF
  Title
Vinculin is a dually regulated actin filament barbed end-capping and side-binding protein.
  Journal
J Biol Chem 285:23420-32 (2010)
DOI:10.1074/jbc.M110.102830
  Sequence
[hsa:7414]

DBGET integrated database retrieval system