| Entry |
|
| Name |
VCL
|
| Definition |
vinculin
|
| Pathway |
| Focal adhesion | | Adherens junction | | Leukocyte transendothelial migration | | Regulation of actin cytoskeleton | | Bacterial invasion of epithelial cells | | Shigellosis | | Amoebiasis |
|
| Disease |
| Hypertrophic cardiomyopathy (HCM) | | Dilated cardiomyopathy (DCM) |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
Cellular Processes
Cell motility
04810 Regulation of actin cytoskeleton
K05700 VCL; vinculin
Cell communication
04510 Focal adhesion
K05700 VCL; vinculin
04520 Adherens junction
K05700 VCL; vinculin
Organismal Systems
Immune system
04670 Leukocyte transendothelial migration
K05700 VCL; vinculin
Human Diseases
Infectious diseases
05131 Shigellosis
K05700 VCL; vinculin
05100 Bacterial invasion of epithelial cells
K05700 VCL; vinculin
05146 Amoebiasis
K05700 VCL; vinculin
 |
| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | TGU: | | ACS: | | XTR: | | DRE: | | TRU: | | OLA: | | BFO: | | CIN: | | SPU: | | DME: | | DPO: | | DAN: | | DER: | | DPE: | | DSE: | | DWI: | | DYA: | | DGR: | | DMO: | | DVI: | | AGA: | | AAG: | | CQU: | | NVI: | | TCA: | | API: | | PHU: | | ISC: | | CEL: | | CBR: | | BMY: | | TSP: | | SMM: | | NVE: | | HMG: | | TAD: | | AQU: | | MBR: | | DDI: | | DPP: | | » show all
   |
| Reference |
|
| Authors |
Le Clainche C, Dwivedi SP, Didry D, Carlier MF |
| Title |
Vinculin is a dually regulated actin filament barbed end-capping and side-binding protein. |
| Journal |
J Biol Chem 285:23420-32 (2010) |