KEGG   ORTHOLOGY: K05718Help
Entry
K05718                      KO                                     

Name
ITGAL
Definition
integrin alpha L
Pathway
Rap1 signaling pathway
Cell adhesion molecules (CAMs)
Natural killer cell mediated cytotoxicity
Leukocyte transendothelial migration
Regulation of actin cytoskeleton
Malaria
Staphylococcus aureus infection
HTLV-I infection
Epstein-Barr virus infection
Rheumatoid arthritis
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K05718  ITGAL; integrin alpha L
  Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    K05718  ITGAL; integrin alpha L
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05718  ITGAL; integrin alpha L
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K05718  ITGAL; integrin alpha L
   04670 Leukocyte transendothelial migration
    K05718  ITGAL; integrin alpha L
 Human Diseases
  Immune diseases
   05323 Rheumatoid arthritis
    K05718  ITGAL; integrin alpha L
  Cardiovascular diseases
   05416 Viral myocarditis
    K05718  ITGAL; integrin alpha L
  Infectious diseases
   05150 Staphylococcus aureus infection
    K05718  ITGAL; integrin alpha L
   05166 HTLV-I infection
    K05718  ITGAL; integrin alpha L
   05169 Epstein-Barr virus infection
    K05718  ITGAL; integrin alpha L
   05144 Malaria
    K05718  ITGAL; integrin alpha L
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K05718  ITGAL; integrin alpha L
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Immune system
   ICAM family
    ICAM1; intercellular adhesion molecule 1
     LFA-1
      K05718 ITGAL; integrin alpha L
    ICAM2; intercellular adhesion molecule 2
     LFA-1
      K05718 ITGAL; integrin alpha L
    ICAM3; intercellular adhesion molecule 3
     LFA-1
      K05718 ITGAL; integrin alpha L
   Others
    CD226, DNAM1; CD226 antigen
     LFA-1
      K05718 ITGAL; integrin alpha L
  Neural system
   N/0 subfamily
    ICAM5, TLCN; intercellular adhesion molecule 5
     LFA-1
      K05718 ITGAL; integrin alpha L
  Others
   ICAM4; intercellular adhesion molecule 4
    LFA-1
     K05718 ITGAL; integrin alpha L
   F11R, JAM1; junctional adhesion molecule 1
    LFA-1
     K05718 ITGAL; integrin alpha L
Cellular antigens [BR:ko04090]
 Proteins
  K05718  CD11a, ITGAL; integrin, alpha L
BRITE hierarchy
Genes
HSA: 
3683(ITGAL)
PTR: 
454045(ITGAL)
PPS: 
100968171(ITGAL)
GGO: 
101139540(ITGAL)
PON: 
NLE: 
100600240(ITGAL)
MCC: 
711945(ITGAL)
MCF: 
CJC: 
100390790(ITGAL)
MMU: 
16408(Itgal)
RNO: 
308995(Itgal)
CGE: 
100770691(Itgal)
HGL: 
101723643(Itgal)
TUP: 
102469543(ITGAL)
CFA: 
489905(ITGAL)
AML: 
100464009(ITGAL)
UMR: 
103657863(ITGAL)
FCA: 
101085940(ITGAL)
PTG: 
102951540(ITGAL)
BTA: 
281874(ITGAL)
BOM: 
102281951(ITGAL)
PHD: 
102342198(ITGAL)
CHX: 
102172115(ITGAL)
OAS: 
641296(ITGAL)
SSC: 
733681(ITGAL)
CFR: 
102519794(ITGAL)
BACU: 
103015686(ITGAL)
LVE: 
103086254(ITGAL)
ECB: 
100065508(ITGAL)
MYB: 
102245292(ITGAL)
MYD: 
102754113(ITGAL)
PALE: 
102879417(ITGAL)
MDO: 
100017790(ITGAL)
SHR: 
100932849(ITGAL)
OAA: 
ASN: 
AMJ: 
PSS: 
CMY: 
102935120(ITGAL)
ACS: 
103280821(itgal)
PBI: 
XTR: 
MZE: 
XMA: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
van der Flier A, Sonnenberg A.
  Title
Function and interactions of integrins.
  Journal
Cell Tissue Res 305:285-98 (2001)
Reference
  Authors
Barczyk M, Carracedo S, Gullberg D
  Title
Integrins.
  Journal
Cell Tissue Res 339:269-80 (2010)

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