KEGG   ORTHOLOGY: K05725Help
Entry
K05725                      KO                                     

Name
PTK2, FAK
Definition
focal adhesion kinase 1 [EC:2.7.10.2]
Pathway
ErbB signaling pathway
Chemokine signaling pathway
PI3K-Akt signaling pathway
Axon guidance
VEGF signaling pathway
Focal adhesion
Leukocyte transendothelial migration
Regulation of actin cytoskeleton
Bacterial invasion of epithelial cells
Amoebiasis
Pathways in cancer
Transcriptional misregulation in cancer
Proteoglycans in cancer
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    K05725  PTK2, FAK; focal adhesion kinase 1
   04370 VEGF signaling pathway
    K05725  PTK2, FAK; focal adhesion kinase 1
   04151 PI3K-Akt signaling pathway
    K05725  PTK2, FAK; focal adhesion kinase 1
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05725  PTK2, FAK; focal adhesion kinase 1
  Cell communication
   04510 Focal adhesion
    K05725  PTK2, FAK; focal adhesion kinase 1
 Organismal Systems
  Immune system
   04670 Leukocyte transendothelial migration
    K05725  PTK2, FAK; focal adhesion kinase 1
   04062 Chemokine signaling pathway
    K05725  PTK2, FAK; focal adhesion kinase 1
  Development
   04360 Axon guidance
    K05725  PTK2, FAK; focal adhesion kinase 1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05725  PTK2, FAK; focal adhesion kinase 1
   05202 Transcriptional misregulation in cancers
    K05725  PTK2, FAK; focal adhesion kinase 1
   05205 Proteoglycans in cancer
    K05725  PTK2, FAK; focal adhesion kinase 1
   05222 Small cell lung cancer
    K05725  PTK2, FAK; focal adhesion kinase 1
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    K05725  PTK2, FAK; focal adhesion kinase 1
   05146 Amoebiasis
    K05725  PTK2, FAK; focal adhesion kinase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     K05725  PTK2, FAK; focal adhesion kinase 1
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  FAK family
   K05725  PTK2, FAK; focal adhesion kinase 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K05725  PTK2, FAK; focal adhesion kinase 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5747(PTK2)
PTR: 
464422(PTK2)
PPS: 
100989953(PTK2)
GGO: 
101128620(PTK2)
PON: 
100447959(PTK2)
MCC: 
700634(PTK2)
MCF: 
MMU: 
14083(Ptk2)
RNO: 
25614(Ptk2)
CGE: 
100759464(Ptk2)
HGL: 
101711587(Ptk2)
TUP: 
102483369(PTK2)
CFA: 
475108(PTK2)
AML: 
FCA: 
101095952(PTK2)
PTG: 
102953254(PTK2)
BTA: 
506270(PTK2)
BOM: 
102280095(PTK2)
PHD: 
102332836(PTK2)
CHX: 
102177814(PTK2)
CFR: 
102516641(PTK2)
BACU: 
103013388(PTK2)
LVE: 
103082438(PTK2)
ECB: 
100058245(PTK2)
MYB: 
102245460(PTK2)
MYD: 
102754742(PTK2)
PALE: 
102898998(PTK2)
MDO: 
100027188(PTK2)
SHR: 
100933019(PTK2)
OAA: 
100076789(PTK2)
GGA: 
396416(PTK2)
MGP: 
TGU: 
100221659(PTK2)
FAB: 
101814936(PTK2)
PHI: 
102104319(PTK2)
APLA: 
101796890(PTK2)
FPG: 
101922646(PTK2)
FCH: 
CLV: 
102093049(PTK2)
ASN: 
102375664(PTK2)
AMJ: 
102569140(PTK2)
PSS: 
102453077(PTK2)
CMY: 
102945262(PTK2)
ACS: 
PBI: 
103060776(PTK2)
XLA: 
XTR: 
733890(ptk2)
DRE: 
142986(ptk2ab) 386705(ptk2aa)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
103181063(ptk2)
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
Dpse_GA10015(Dpse_fak)
DAN: 
DER: 
DPE: 
DSE: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
724973(PTK2)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CELE_C30F8.4(kin-32)
CBR: 
CBG10801(Cbr-kin-32)
BMY: 
LOA: 
SMM: 
HMG: 
TAD: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Schaller MD
  Title
Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions.
  Journal
J Cell Sci 123:1007-13 (2010)

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