KEGG   ORTHOLOGY: K05733Help
Entry
K05733                      KO                                     
Name
PAK3, MRX30
Definition
p21-activated kinase 3 [EC:2.7.11.1]
Pathway
ErbB signaling pathway
Axon guidance
Focal adhesion
T cell receptor signaling pathway
Regulation of actin cytoskeleton
Renal cell carcinoma
Disease
H00480  
Non-syndromic X-linked mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    K05733  PAK3, MRX30; p21-activated kinase 3
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05733  PAK3, MRX30; p21-activated kinase 3
  Cell communication
   04510 Focal adhesion
    K05733  PAK3, MRX30; p21-activated kinase 3
 Organismal Systems
  Immune system
   04660 T cell receptor signaling pathway
    K05733  PAK3, MRX30; p21-activated kinase 3
  Development
   04360 Axon guidance
    K05733  PAK3, MRX30; p21-activated kinase 3
 Human Diseases
  Cancers
   05211 Renal cell carcinoma
    K05733  PAK3, MRX30; p21-activated kinase 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K05733  PAK3, MRX30; p21-activated kinase 3
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: STE group
  STE20 family
   K05733  PAK3, MRX30; p21-activated kinase 3
BRITE hierarchy
Genes
HSA: 
5063(PAK3)
PTR: 
450118(PAK3)
PPS: 
100988375(PAK3)
GGO: 
101141425(PAK3)
PON: 
100294571(PAK3)
MCC: 
706217(PAK3)
MMU: 
18481(Pak3)
RNO: 
29433(Pak3)
CFA: 
492067(PAK3)
AML: 
100481001(PAK3)
FCA: 
101092248(PAK3)
BTA: 
534526(PAK3)
SSC: 
100622334 100624533
ECB: 
100054315(PAK3)
MDO: 
100012727
SHR: 
100926699(PAK3)
GGA: 
422342(PAK3)
MGP: 
100539360
TGU: 
100218271 100220716(PAK3)
ACS: 
100552681
XLA: 
378493(pak3)
XTR: 
100495025
TRU: 
101070991
OLA: 
101162700
SPU: 
576091
MBR: 
MONBRDRAFT_36217
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Bokoch GM
  Title
Biology of the p21-activated kinases.
  Journal
Annu Rev Biochem 72:743-81 (2003)
Reference
  Authors
Hofmann C, Shepelev M, Chernoff J
  Title
The genetics of Pak.
  Journal
J Cell Sci 117:4343-54 (2004)
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