KEGG   ORTHOLOGY: K05742Help
Entry
K05742                      KO                                     
Name
SLC9A1, NHE1
Definition
solute carrier family 9 (sodium/hydrogen exchanger), member 1
Pathway
cAMP signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Regulation of actin cytoskeleton
Thyroid hormone signaling pathway
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04024 cAMP signaling pathway
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
  Circulatory system
   04260 Cardiac muscle contraction
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04261 Adrenergic signaling in cardiomyocytes
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
  Digestive system
   04970 Salivary secretion
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04971 Gastric acid secretion
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04972 Pancreatic secretion
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04976 Bile secretion
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
Transporters [BR:ko02000]
 Solute Carrier Family (SLC)
  SLC9: Na+/H+ exchanger
   K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
BRITE hierarchy
Other DBs
Genes
HSA: 
6548(SLC9A1)
PTR: 
456669(SLC9A1)
PPS: 
100995124(SLC9A1)
GGO: 
101134383(SLC9A1)
PON: 
NLE: 
100581293(SLC9A1)
MCC: 
720079 720142(SLC9A1)
MCF: 
CJC: 
100388466(SLC9A1)
MMU: 
20544(Slc9a1)
RNO: 
24782(Slc9a1)
CGE: 
100689320(Slc9a1)
NGI: 
103737082(Slc9a1)
HGL: 
101724784(Slc9a1)
OCU: 
100009586(SLC9A1)
TUP: 
102501147(SLC9A1)
CFA: 
478171(SLC9A1)
AML: 
100478707(SLC9A1)
UMR: 
103666507(SLC9A1)
FCA: 
101088766(SLC9A1)
PTG: 
102956531(SLC9A1)
BTA: 
317654(SLC9A1)
BOM: 
102275424(SLC9A1)
PHD: 
102327464 102344308
CHX: 
102179249(SLC9A1)
OAS: 
494435(SLC9A1)
SSC: 
397458(SLC9A1)
CFR: 
102517893(SLC9A1)
BACU: 
103013771(SLC9A1)
LVE: 
103083053(SLC9A1)
ECB: 
100070959(SLC9A1)
MYB: 
102260344(SLC9A1)
MYD: 
102754223(SLC9A1)
PALE: 
102888463(SLC9A1)
MDO: 
100017140(SLC9A1)
SHR: 
100927417 100929350
OAA: 
100088668(SLC9A1)
GGA: 
419580(SLC9A1)
MGP: 
100008573(SLC9A1)
APLA: 
101803574(SLC9A1)
TGU: 
100229450(SLC9A1)
FAB: 
101817623(SLC9A1)
PHI: 
102103995(SLC9A1)
CCW: 
104694731(SLC9A1)
FPG: 
101911642(SLC9A1)
FCH: 
102059778(SLC9A1)
CLV: 
102086647(SLC9A1)
ASN: 
102370779(SLC9A1)
AMJ: 
102575554(SLC9A1)
PSS: 
102447706(SLC9A1)
CMY: 
102944004(SLC9A1)
ACS: 
100555032(slc9a1)
PBI: 
103064198(SLC9A1)
XLA: 
397917(slc9a1)
XTR: 
100496739(slc9a1)
DRE: 
100538277 101885761 795135(slc9a1)
TRU: 
101067841 101068533
MZE: 
101464569 101464596
OLA: 
101159279 101169232
XMA: 
102218019 102232120
LCM: 
102351735(SLC9A1) 102355203
CMK: 
103179577(slc9a1)
HRO: 
HELRODRAFT_70084
MBR: 
MONBRDRAFT_29272
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Malo ME, Fliegel L
  Title
Physiological role and regulation of the Na+/H+ exchanger.
  Journal
Can J Physiol Pharmacol 84:1081-95 (2006)
Reference
  Authors
Brett CL, Donowitz M, Rao R
  Title
Evolutionary origins of eukaryotic sodium/proton exchangers.
  Journal
Am J Physiol Cell Physiol 288:C223-39 (2005)
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