KEGG   ORTHOLOGY: K05742Help
Entry
K05742                      KO                                     

Name
SLC9A1, NHE1
Definition
solute carrier family 9 (sodium/hydrogen exchanger), member 1
Pathway
cAMP signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Apelin signaling pathway
Regulation of actin cytoskeleton
Thyroid hormone signaling pathway
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Proteoglycans in cancer
Disease
H01891  
Autosomal recessive spinocerebellar ataxias
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04371 Apelin signaling pathway
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04024 cAMP signaling pathway
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
  Circulatory system
   04260 Cardiac muscle contraction
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04261 Adrenergic signaling in cardiomyocytes
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
  Digestive system
   04970 Salivary secretion
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04971 Gastric acid secretion
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04972 Pancreatic secretion
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
   04976 Bile secretion
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
Transporters [BR:ko02000]
 Solute Carrier Family (SLC)
  SLC9: Na+/H+ exchanger
   K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
BRITE hierarchy
Other DBs
Genes
HSA: 
6548(SLC9A1)
PTR: 
456669(SLC9A1)
PPS: 
100995124(SLC9A1)
GGO: 
101134383(SLC9A1)
PON: 
NLE: 
100581293(SLC9A1)
MCC: 
720079(SLC9A1) 720142(SLC9A1)
MCF: 
101865259(SLC9A1)
CSAB: 
103225299(SLC9A1)
RRO: 
104675732(SLC9A1)
RBB: 
108518204(SLC9A1)
CJC: 
100388466(SLC9A1)
SBQ: 
101042099(SLC9A1)
MMU: 
20544(Slc9a1)
RNO: 
24782(Slc9a1)
CGE: 
100689320(Slc9a1)
NGI: 
103737082(Slc9a1)
HGL: 
101724784(Slc9a1)
CCAN: 
109698756(Slc9a1)
OCU: 
100009586(SLC9A1)
TUP: 
102501147(SLC9A1)
CFA: 
478171(SLC9A1)
AML: 
100478707(SLC9A1)
UMR: 
103666507(SLC9A1)
ORO: 
101369980(SLC9A1)
FCA: 
101088766(SLC9A1)
PTG: 
102956531(SLC9A1)
AJU: 
106977548(SLC9A1)
BTA: 
317654(SLC9A1)
BOM: 
102275424(SLC9A1)
BIU: 
109573208(SLC9A1)
PHD: 
CHX: 
102179249(SLC9A1)
OAS: 
494435(SLC9A1)
SSC: 
397458(SLC9A1)
CFR: 
102517893(SLC9A1)
CDK: 
105100703(SLC9A1)
BACU: 
103013771(SLC9A1)
LVE: 
103083053(SLC9A1)
ECB: 
100070959(SLC9A1)
EPZ: 
103550531(SLC9A1)
EAI: 
106839089(SLC9A1)
MYB: 
102260344(SLC9A1)
MYD: 
102754223(SLC9A1)
HAI: 
109386737(SLC9A1)
RSS: 
109449189(SLC9A1)
PALE: 
102888463(SLC9A1)
LAV: 
104846349(SLC9A1)
TMU: 
MDO: 
100017140(SLC9A1)
SHR: 
OAA: 
100088668(SLC9A1)
GGA: 
419580(SLC9A1)
MGP: 
100008573(SLC9A1)
CJO: 
107323990(SLC9A1)
APLA: 
101803574(SLC9A1)
ACYG: 
106047889(SLC9A1)
TGU: 
100229450(SLC9A1)
GFR: 
102032850(SLC9A1)
FAB: 
101817623(SLC9A1)
PHI: 
102103995(SLC9A1)
PMAJ: 
107214153(SLC9A1)
CCW: 
104694731(SLC9A1)
FPG: 
101911642(SLC9A1)
FCH: 
102059778(SLC9A1)
CLV: 
102086647(SLC9A1)
EGZ: 
104134879(SLC9A1)
ASN: 
102370779(SLC9A1)
AMJ: 
102575554(SLC9A1)
PSS: 
102447706(SLC9A1)
CMY: 
102944004(SLC9A1)
CPIC: 
101944127(SLC9A1)
ACS: 
100555032(slc9a1)
PVT: 
110090947(SLC9A1)
PBI: 
103064198(SLC9A1)
GJA: 
107110810(SLC9A1)
XLA: 
108708100(slc9a1.L) 397917(slc9a1.S)
XTR: 
100496739(slc9a1)
NPR: 
108790812(SLC9A1)
DRE: 
101885761(slc9a1a) 795135(slc9a1b)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
PRET: 
NFU: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
103179577(slc9a1)
HRO: 
MBR: 
SRE: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2536298
  Authors
Sardet C, Franchi A, Pouyssegur J
  Title
Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter.
  Journal
Cell 56:271-80 (1989)
DOI:10.1016/0092-8674(89)90901-X
  Sequence
[hsa:6548]

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