KEGG   ORTHOLOGY: K05747Help
Entry
K05747                      KO                                     

Name
WAS
Definition
Wiskott-Aldrich syndrome protein
Pathway
Chemokine signaling pathway
Adherens junction
Fc gamma R-mediated phagocytosis
Regulation of actin cytoskeleton
Bacterial invasion of epithelial cells
Pathogenic Escherichia coli infection
Shigellosis
Salmonella infection
Choline metabolism in cancer
Disease
H00100  
Neutropenic disorders
H00107  
Other well-defined immunodeficiency syndromes
H00978  
Thrombocytopenia (THC)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05747  WAS; Wiskott-Aldrich syndrome protein
  Cellular commiunity
   04520 Adherens junction
    K05747  WAS; Wiskott-Aldrich syndrome protein
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    K05747  WAS; Wiskott-Aldrich syndrome protein
   04062 Chemokine signaling pathway
    K05747  WAS; Wiskott-Aldrich syndrome protein
 Human Diseases
  Cancers
   05231 Choline metabolism in cancer
    K05747  WAS; Wiskott-Aldrich syndrome protein
  Infectious diseases
   05130 Pathogenic Escherichia coli infection
    K05747  WAS; Wiskott-Aldrich syndrome protein
   05132 Salmonella infection
    K05747  WAS; Wiskott-Aldrich syndrome protein
   05131 Shigellosis
    K05747  WAS; Wiskott-Aldrich syndrome protein
   05100 Bacterial invasion of epithelial cells
    K05747  WAS; Wiskott-Aldrich syndrome protein
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    WASP / WAVE
     K05747  WAS; Wiskott-Aldrich syndrome protein
BRITE hierarchy
Genes
HSA: 
7454(WAS) 8976(WASL)
PTR: 
463688(WASL)
GGO: 
PON: 
100171409(WASL) 100452449(WAS)
MCC: 
MMU: 
22376(Was) 73178(Wasl)
RNO: 
317371(Was) 682507(Wasl)
CFA: 
475213(WASL) 491867(WAS)
AML: 
100472179(WASL) 100479480(WAS)
BTA: 
100336547(WAS) 281577(WASL)
SSC: 
100525017(WASL)
ECB: 
MDO: 
100013566(WASL) 100018699(WAS)
OAA: 
100076423(WASL) 100089883(WAS)
GGA: 
417750(WASL)
MGP: 
100542107(WASL)
TGU: 
100228869(WASL)
XLA: 
XTR: 
407864(wasl) 496673(was)
DRE: 
100009637(wasla) 335158(wasb) 394034(waslb) 571256(wasa)
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DGR: 
AGA: 
AAG: 
CQU: 
AME: 
409218(WASp)
NVI: 
TCA: 
API: 
CEL: 
CBR: 
CBG01563(Cbr-wsp-1)
BMY: 
SMM: 
NVE: 
HMG: 
TAD: 
SCE: 
YOR181W(LAS17)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0F00390(NCAS0F00390)
NDI: 
NDAI_0D02710(NDAI0D02710)
TPF: 
TPHA_0F02690(TPHA0F02690)
TBL: 
TBLA_0E01040(TBLA0E01040)
TDL: 
TDEL_0G03900(TDEL0G03900)
KAF: 
KAFR_0G02420(KAFR0G02420)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CaO19.6598(LAS17)
CTP: 
COT: 
CDU: 
YLI: 
CLU: 
NCR: 
NTE: 
NEUTE1DRAFT125189(NEUTE1DRAFT_125189)
SMP: 
TTT: 
MTM: 
CTHR: 
FGR: 
FPU: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VDA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_236094(AO090120000140)
ANG: 
ANI_1_2136104(An12g07930)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
PBN: 
URE: 
ABE: 
TVE: 
AJE: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
TML: 
SPO: 
CNE: 
PPL: 
PCO: 
SHS: 
FME: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT101672(AGABI1DRAFT_101672)
ABV: 
AGABI2DRAFT153764(AGABI2DRAFT_153764)
CPUT: 
UMA: 
PGR: 
MLR: 
WSE: 
MBR: 
DDI: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Miki H, Takenawa T
  Title
Regulation of actin dynamics by WASP family proteins.
  Journal
J Biochem 134:309-13 (2003)
Reference
  Authors
Cory GO, Garg R, Cramer R, Ridley AJ
  Title
Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein.
  Journal
J Biol Chem 277:45115-21 (2002)
  Sequence
[hsa:7454]

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