KEGG   ORTHOLOGY: K06060Help
Entry
K06060                      KO                                     

Name
PSENN
Definition
presenilin, other
Pathway
Notch signaling pathway
Module
M00682  
Notch signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04330 Notch signaling pathway
    K06060  PSENN; presenilin, other
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00682  Notch signaling
     K06060  PSENN; presenilin, other
Peptidases [BR:ko01002]
 Aspartic Peptidases
  Family A22: presenilin family
   K06060  PSENN; presenilin, other
BRITE hierarchy
Genes
CEL: 
CBR: 
CBG11944(Cbr-spe-4) CBG12097(Cbr-hop-1)
BMY: 
TaxonomyKoalaUniProt
Reference
  Authors
Westlund B, Parry D, Clover R, Basson M, Johnson CD
  Title
Reverse genetic analysis of Caenorhabditis elegans presenilins reveals redundant  but unequal roles for sel-12 and hop-1 in Notch-pathway signaling.
  Journal
Proc Natl Acad Sci U S A 96:2497-502 (1999)
Reference
PMID:9819355
  Authors
Arduengo PM, Appleberry OK, Chuang P, L'Hernault SW
  Title
The presenilin protein family member SPE-4 localizes to an ER/Golgi derived organelle and is required for proper cytoplasmic partitioning during Caenorhabditis elegans spermatogenesis.
  Journal
J Cell Sci 111 ( Pt 24):3645-54 (1998)

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