KEGG   ORTHOLOGY: K06270Help
Entry
K06270                      KO                                     

Name
PPP1R12A, MYPT1
Definition
protein phosphatase 1 regulatory subunit 12A
Pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Vascular smooth muscle contraction
Focal adhesion
Platelet activation
Regulation of actin cytoskeleton
Oxytocin signaling pathway
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04024 cAMP signaling pathway
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
   04022 cGMP - PKG signaling pathway
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
  Cellular commiunity
   04510 Focal adhesion
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
 Organismal Systems
  Immune system
   04611 Platelet activation
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
  Endocrine system
   04921 Oxytocin signaling pathway
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
  Circulatory system
   04270 Vascular smooth muscle contraction
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
BRITE hierarchy
Genes
HSA: 
4659(PPP1R12A)
PTR: 
452095(PPP1R12A)
PPS: 
100989468(PPP1R12A)
GGO: 
PON: 
100172617(PPP1R12A)
NLE: 
100602476(PPP1R12A)
MCC: 
695735(PPP1R12A)
MCF: 
CJC: 
100393191(PPP1R12A)
MMU: 
17931(Ppp1r12a)
RNO: 
116670(Ppp1r12a)
CGE: 
100754718(Ppp1r12a)
NGI: 
103749250(Ppp1r12a)
HGL: 
101700150(Ppp1r12a)
OCU: 
100350558(PPP1R12A)
TUP: 
102473894(PPP1R12A)
CFA: 
475411(PPP1R12A)
AML: 
100483995(PPP1R12A)
UMR: 
103680852(PPP1R12A)
FCA: 
101089624(PPP1R12A)
PTG: 
102951696(PPP1R12A)
BTA: 
538606(PPP1R12A)
BOM: 
102268036(PPP1R12A)
PHD: 
102339658(PPP1R12A)
CHX: 
102183294(PPP1R12A)
OAS: 
641303(PPP1R12A)
SSC: 
397190(PPP1R12A)
CFR: 
102511361(PPP1R12A)
BACU: 
103020020(PPP1R12A)
LVE: 
103071997(PPP1R12A)
ECB: 
100060501(PPP1R12A)
MYB: 
102251394(PPP1R12A)
MYD: 
102765262(PPP1R12A)
PALE: 
102898474(PPP1R12A)
MDO: 
100019488(PPP1R12A)
SHR: 
OAA: 
GGA: 
396020(PPP1R12A)
MGP: 
APLA: 
101800288(PPP1R12A)
TGU: 
100220857(PPP1R12A)
FAB: 
101822232(PPP1R12A)
PHI: 
102107346(PPP1R12A)
FPG: 
101914871(PPP1R12A)
FCH: 
102052384(PPP1R12A)
CLV: 
102098984(PPP1R12A)
ASN: 
102381466(PPP1R12A)
AMJ: 
102562278(PPP1R12A)
PSS: 
102460329(PPP1R12A)
CMY: 
102930708(PPP1R12A)
ACS: 
100560455(ppp1r12a)
PBI: 
103053749(PPP1R12A)
XTR: 
DRE: 
445393(ppp1r12a) 571837
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
726541(Mbs)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CELE_C06C3.1(mel-11)
CBR: 
CBG00870(Cbr-mel-11)
BMY: 
LOA: 
HRO: 
LGI: 
SMM: 
NVE: 
HMG: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Grassie ME, Moffat LD, Walsh MP, MacDonald JA
  Title
The myosin phosphatase targeting protein (MYPT) family: a regulated mechanism for achieving substrate specificity of the catalytic subunit of protein phosphatase type 1delta.
  Journal
Arch Biochem Biophys 510:147-59 (2011)

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