KEGG   ORTHOLOGY: K06270Help
Entry
K06270                      KO                                     

Name
PPP1R12A, MYPT1
Definition
protein phosphatase 1 regulatory subunit 12A
Pathway
ko04022  cGMP-PKG signaling pathway
ko04024  cAMP signaling pathway
ko04270  Vascular smooth muscle contraction
ko04510  Focal adhesion
ko04611  Platelet activation
ko04810  Regulation of actin cytoskeleton
ko04921  Oxytocin signaling pathway
ko05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04024 cAMP signaling pathway
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
   04022 cGMP - PKG signaling pathway
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
 Organismal Systems
  Immune system
   04611 Platelet activation
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
  Endocrine system
   04921 Oxytocin signaling pathway
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
  Circulatory system
   04270 Vascular smooth muscle contraction
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
BRITE hierarchy
Genes
HSA: 4659(PPP1R12A)
PTR: 452095(PPP1R12A)
PPS: 100989468(PPP1R12A)
GGO: 101139376(PPP1R12A)
PON: 100172617(PPP1R12A)
NLE: 100602476(PPP1R12A)
MCC: 695735(PPP1R12A)
MCF: 101864805(PPP1R12A)
CSAB: 103238782(PPP1R12A)
RRO: 104653889 104675773(PPP1R12A)
RBB: 108528527(PPP1R12A)
CJC: 100393191(PPP1R12A)
SBQ: 101034840(PPP1R12A)
MMU: 17931(Ppp1r12a)
RNO: 116670(Ppp1r12a)
CGE: 100754718(Ppp1r12a)
NGI: 103749250(Ppp1r12a)
HGL: 101700150(Ppp1r12a)
CCAN: 109697808(Ppp1r12a)
OCU: 100350558(PPP1R12A)
TUP: 102473894(PPP1R12A)
CFA: 475411(PPP1R12A)
AML: 100483995(PPP1R12A)
UMR: 103680852(PPP1R12A)
ORO: 101384536(PPP1R12A)
FCA: 101089624(PPP1R12A)
PTG: 102951696(PPP1R12A)
AJU: 106967400(PPP1R12A)
BTA: 538606(PPP1R12A)
BOM: 102268036(PPP1R12A)
BIU: 109558936(PPP1R12A)
PHD: 102339658(PPP1R12A)
CHX: 102183294(PPP1R12A)
OAS: 641303(PPP1R12A)
SSC: 397190(PPP1R12A)
CFR: 102511361(PPP1R12A)
CDK: 105084895(PPP1R12A)
BACU: 103020020(PPP1R12A)
LVE: 103071997(PPP1R12A)
OOR: 101279306(PPP1R12A)
ECB: 100060501(PPP1R12A)
EPZ: 103549928(PPP1R12A)
EAI: 106831522(PPP1R12A)
MYB: 102251394(PPP1R12A)
MYD: 102765262(PPP1R12A)
HAI: 109375211(PPP1R12A)
RSS: 109457972(PPP1R12A)
PALE: 102898474(PPP1R12A)
LAV: 100673922(PPP1R12A)
TMU: 101341352
MDO: 100019488(PPP1R12A)
SHR: 100926931(PPP1R12A)
OAA: 100074159(PPP1R12A) 100077235
GGA: 396020(PPP1R12A)
MGP: 100539276(PPP1R12A)
CJO: 107311018(PPP1R12A)
APLA: 101800288(PPP1R12A)
ACYG: 106046454(PPP1R12A)
TGU: 100220857(PPP1R12A)
GFR: 102037308(PPP1R12A)
FAB: 101822232(PPP1R12A)
PHI: 102107346(PPP1R12A)
PMAJ: 107204392(PPP1R12A)
CCW: 104698411(PPP1R12A)
FPG: 101914871(PPP1R12A)
FCH: 102052384(PPP1R12A)
CLV: 102098984(PPP1R12A)
EGZ: 104132935(PPP1R12A)
AAM: 106488611(PPP1R12A)
ASN: 102381466(PPP1R12A)
AMJ: 102562278(PPP1R12A)
PSS: 102460329(PPP1R12A)
CMY: 102930708(PPP1R12A)
CPIC: 101949705(PPP1R12A)
ACS: 100560455(ppp1r12a)
PVT: 110084990(PPP1R12A)
PBI: 103053749(PPP1R12A)
GJA: 107113829(PPP1R12A)
XLA: 108711109(ppp1r12a.L) 108713841 108715193 733200(ppp1r12a.S)
XTR: 100487727 100493563(ppp1r12a)
NPR: 108794189 108799788(PPP1R12A)
DRE: 445393(ppp1r12a) 571837(zmp:0000001167)
IPU: 108274702 108279475(ppp1r12a)
AMEX: 103030184 103046804(ppp1r12a)
TRU: 101079088
LCO: 104924035(ppp1r12a) 104928858
NCC: 104949170(ppp1r12a) 104956193
MZE: 101469187 101484034(ppp1r12a)
OLA: 101161524(ppp1r12a)
XMA: 102218333(ppp1r12a) 102229096
PRET: 103459134(ppp1r12a) 103466502
NFU: 107386601(ppp1r12a) 107388676
CSEM: 103380280 103382552(ppp1r12a)
LCF: 108873647(ppp1r12a) 108886890
HCQ: 109507600 109530079(ppp1r12a)
BPEC: 110161521(ppp1r12a) 110169303
ELS: 105018059 105020291(ppp1r12a)
SFM: 108936554(ppp1r12a) 108941213 108942353
LCM: 102353430 102356119(PPP1R12A)
CMK: 103179091 103179864(ppp1r12a) 103190176
CIN: 100187107
SPU: 591869
APLC: 110986335
SKO: 102807891
DME: Dmel_CG32156(Mbs)
DSI: Dsimw501_GD14592(Dsim_GD14592)
MDE: 101890302
AAG: 5576767
AME: 726541(Mbs)
BIM: 100749351
BTER: 100646538
SOC: 105198893
AEC: 105145669
ACEP: 105617107
PBAR: 105426810
HST: 105192635
CFO: 105251152
LHU: 105677120
PGC: 109854374
NVI: 100114433
TCA: 659634
DPA: 109542291
NVL: 108565232
BMOR: 101737973
PMAC: 106717251
PRAP: 110999489
PXY: 105382686
ZNE: 110827706
FCD: 110851499
TUT: 107361894
CEL: CELE_C06C3.1(mel-11)
CBR: CBG00870(Cbr-mel-11)
BMY: Bm1_46800
CRG: 105330003
MYI: 110459072
LAK: 106178432
ADF: 107343486
HMG: 100214665
AQU: 100637344
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Grassie ME, Moffat LD, Walsh MP, MacDonald JA
  Title
The myosin phosphatase targeting protein (MYPT) family: a regulated mechanism for achieving substrate specificity of the catalytic subunit of protein phosphatase type 1delta.
  Journal
Arch Biochem Biophys 510:147-59 (2011)
DOI:10.1016/j.abb.2011.01.018

DBGET integrated database retrieval system