| Entry |
|
| Name |
CD28
|
| Definition |
CD28 antigen
|
| Pathway |
| Cell adhesion molecules (CAMs) | | T cell receptor signaling pathway | | Intestinal immune network for IgA production | | Type I diabetes mellitus | | Measles | | Autoimmune thyroid disease | | Systemic lupus erythematosus | | Rheumatoid arthritis | | Allograft rejection | | Graft-versus-host disease | | Viral myocarditis |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
Environmental Information Processing
Signaling molecules and interaction
04514 Cell adhesion molecules (CAMs)
K06470 CD28; CD28 antigen
Organismal Systems
Immune system
04660 T cell receptor signaling pathway
K06470 CD28; CD28 antigen
04672 Intestinal immune network for IgA production
K06470 CD28; CD28 antigen
Human Diseases
Immune diseases
05322 Systemic lupus erythematosus
K06470 CD28; CD28 antigen
05323 Rheumatoid arthritis
K06470 CD28; CD28 antigen
05320 Autoimmune thyroid disease
K06470 CD28; CD28 antigen
05330 Allograft rejection
K06470 CD28; CD28 antigen
05332 Graft-versus-host disease
K06470 CD28; CD28 antigen
Cardiovascular diseases
05416 Viral myocarditis
K06470 CD28; CD28 antigen
Endocrine and metabolic diseases
04940 Type I diabetes mellitus
K06470 CD28; CD28 antigen
Infectious diseases
05162 Measles
K06470 CD28; CD28 antigen
Cell adhesion molecules and their ligands [BR:ko04516]
1. Immunoglobulin Superfamily
Immune system
B7-CD28 family
CD80; CD80 antigen
K06470 CD28; CD28 antigen
CD86; CD86 antigen
K06470 CD28; CD28 antigen
ICOSLG, ICOSL; inducible T-cell co-stimulator ligand
K06470 CD28; CD28 antigen
Cellular antigens [BR:ko04090]
Proteins
K06470 CD28; CD28 antigen (Tp44)
 |
| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | TGU: | | ACS: | | XLA: | | XTR: | | TRU: | | OLA: | | » show all
   |
| Reference |
|
| Authors |
Chen L. |
| Title |
Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity. |
| Journal |
Nat Rev Immunol 4:336-47 (2004) |