KEGG   ORTHOLOGY: K06481Help
Entry
K06481                      KO                                     
Name
ITGA2
Definition
integrin alpha 2
Pathway
Phagosome
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Hematopoietic cell lineage
Regulation of actin cytoskeleton
Pathways in cancer
Proteoglycans in cancer
Small cell lung cancer
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K06481  ITGA2; integrin alpha 2
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06481  ITGA2; integrin alpha 2
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K06481  ITGA2; integrin alpha 2
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06481  ITGA2; integrin alpha 2
  Cell communication
   04510 Focal adhesion
    K06481  ITGA2; integrin alpha 2
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K06481  ITGA2; integrin alpha 2
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K06481  ITGA2; integrin alpha 2
   05205 Proteoglycans in cancer
    K06481  ITGA2; integrin alpha 2
   05222 Small cell lung cancer
    K06481  ITGA2; integrin alpha 2
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K06481  ITGA2; integrin alpha 2
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06481  ITGA2; integrin alpha 2
   05414 Dilated cardiomyopathy (DCM)
    K06481  ITGA2; integrin alpha 2
Cell adhesion molecules and their ligands [BR:ko04516]
 2. Integrin Family
  Beta1 integrins
   VLA-3
    ITGB1; integrin beta 1
     VLA-2
      K06481 ITGA2; integrin alpha 2
 5. Cadherin Family
  Classic Cadherins
   Vertebrate Type I classic cadherins
    CDHE, CDH1; cadherin 1, type 1, E-cadherin
     VLA-2
      K06481 ITGA2; integrin alpha 2
Cellular antigens [BR:ko04090]
 Proteins
  K06481  CD49b, ITGA2; integrin, alpha 2
BRITE hierarchy
Genes
HSA: 
3673(ITGA2)
PTR: 
471550(ITGA2)
PPS: 
100978441(ITGA2)
GGO: 
101127372(ITGA2)
MCC: 
703572(ITGA2)
MMU: 
16398(Itga2)
RNO: 
170921(Itga2)
CFA: 
489208(ITGA2)
AML: 
FCA: 
101090237(ITGA2)
BTA: 
281872(ITGA2)
SSC: 
397483(ITGA2)
ECB: 
100063367
MDO: 
100031498
GGA: 
100857227
TGU: 
100221336(ITGA2)
ACS: 
100564306
XTR: 
100492714(itga2)
DRE: 
100536533
TRU: 
101065018
OLA: 
101174027
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
van der Flier A, Sonnenberg A.
  Title
Function and interactions of integrins.
  Journal
Cell Tissue Res 305:285-98 (2001)
Reference
  Authors
Barczyk M, Carracedo S, Gullberg D
  Title
Integrins.
  Journal
Cell Tissue Res 339:269-80 (2010)
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