KEGG   ORTHOLOGY: K06482Help
Entry
K06482                      KO                                     

Name
ITGA3
Definition
integrin alpha 3
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Hematopoietic cell lineage
Regulation of actin cytoskeleton
Pathways in cancer
Small cell lung cancer
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K06482  ITGA3; integrin alpha 3
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06482  ITGA3; integrin alpha 3
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06482  ITGA3; integrin alpha 3
  Cell communication
   04510 Focal adhesion
    K06482  ITGA3; integrin alpha 3
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K06482  ITGA3; integrin alpha 3
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K06482  ITGA3; integrin alpha 3
   05222 Small cell lung cancer
    K06482  ITGA3; integrin alpha 3
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K06482  ITGA3; integrin alpha 3
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06482  ITGA3; integrin alpha 3
   05414 Dilated cardiomyopathy (DCM)
    K06482  ITGA3; integrin alpha 3
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K06482  ITGA3; integrin alpha 3
Cell adhesion molecules and their ligands [BR:ko04516]
 2. Integrin Family
  Beta1 integrins
   VLA-2
    ITGB1; integrin beta 1
     VLA-3
      K06482 ITGA3; integrin alpha 3
   VLA-3
    ITGB1; integrin beta 1
     VLA-3
      K06482 ITGA3; integrin alpha 3
Cellular antigens [BR:ko04090]
 Proteins
  K06482  CD49c, ITGA3; integrin, alpha 3
BRITE hierarchy
Genes
HSA: 
3675(ITGA3)
PTR: 
455111(ITGA3)
PPS: 
100993709(ITGA3)
GGO: 
PON: 
100459915(ITGA3)
MCC: 
700962(ITGA3)
MCF: 
102123329(ITGA3)
MMU: 
16400(Itga3)
RNO: 
360606(Itga3)
CGE: 
HGL: 
101699399(Itga3)
TUP: 
102476747(ITGA3)
CFA: 
491074(ITGA3)
AML: 
FCA: 
101093156(ITGA3)
PTG: 
102966946(ITGA3)
BTA: 
508490(ITGA3)
BOM: 
102266712(ITGA3)
PHD: 
102330470(ITGA3)
CHX: 
102185499(ITGA3)
SSC: 
100517053(ITGA3)
CFR: 
102508309(ITGA3)
ECB: 
100056202(ITGA3)
MYB: 
102245715(ITGA3)
MYD: 
102751287(ITGA3)
PALE: 
102884713(ITGA3)
MDO: 
SHR: 
100928379(ITGA3)
OAA: 
100080433(ITGA3)
GGA: 
373946(ITGA3)
FAB: 
101812468(ITGA3)
PHI: 
102105462(ITGA3)
FPG: 
101915907(ITGA3)
FCH: 
102055031(ITGA3)
CLV: 
102092573(ITGA3)
ASN: 
102379676(ITGA3)
CMY: 
102938482(ITGA3)
ACS: 
XTR: 
DRE: 
100331874(itga3b) 407685(itga3a)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102347243(ITGA3)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
van der Flier A, Sonnenberg A.
  Title
Function and interactions of integrins.
  Journal
Cell Tissue Res 305:285-98 (2001)
Reference
  Authors
Barczyk M, Carracedo S, Gullberg D
  Title
Integrins.
  Journal
Cell Tissue Res 339:269-80 (2010)

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