KEGG   ORTHOLOGY: K06485Help
Entry
K06485                      KO                                     

Name
ITGA6
Definition
integrin alpha 6
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Cell adhesion molecules (CAMs)
Hematopoietic cell lineage
Regulation of actin cytoskeleton
Toxoplasmosis
Pathways in cancer
Small cell lung cancer
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Disease
H00586  
Epidermolysis bullosa, junctional
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K06485  ITGA6; integrin alpha 6
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06485  ITGA6; integrin alpha 6
   04514 Cell adhesion molecules (CAMs)
    K06485  ITGA6; integrin alpha 6
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06485  ITGA6; integrin alpha 6
  Cellular community
   04510 Focal adhesion
    K06485  ITGA6; integrin alpha 6
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K06485  ITGA6; integrin alpha 6
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K06485  ITGA6; integrin alpha 6
   05222 Small cell lung cancer
    K06485  ITGA6; integrin alpha 6
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K06485  ITGA6; integrin alpha 6
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06485  ITGA6; integrin alpha 6
   05414 Dilated cardiomyopathy (DCM)
    K06485  ITGA6; integrin alpha 6
  Infectious diseases
   05145 Toxoplasmosis
    K06485  ITGA6; integrin alpha 6
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K06485  ITGA6; integrin alpha 6
  Exosomal proteins of breast milk
   K06485  ITGA6; integrin alpha 6
Cell adhesion molecules and their ligands [BR:ko04516]
 7. Others
  SDC1; syndecan 1
   alpha 6 beta 4
    K06485 ITGA6; integrin alpha 6
  SDC4; syndecan 4
   alpha 6 beta 4
    K06485 ITGA6; integrin alpha 6
Cellular antigens [BR:ko04090]
 Proteins
  K06485  CD49f, ITGA6; integrin, alpha 6
BRITE hierarchy
Genes
HSA: 
3655(ITGA6)
PTR: 
459742(ITGA6)
PPS: 
100967602(ITGA6)
GGO: 
101146479(ITGA6)
PON: 
100442478(ITGA6)
NLE: 
100600735(ITGA6)
MCC: 
697643(ITGA6)
MCF: 
101925271(ITGA6)
CSAB: 
103217327(ITGA6)
RRO: 
104673514(ITGA6)
CJC: 
100403557(ITGA6)
SBQ: 
101045102(ITGA6)
MMU: 
16403(Itga6)
RNO: 
114517(Itga6)
CGE: 
100769534(Itga6)
NGI: 
103751741(Itga6)
HGL: 
101705215(Itga6)
OCU: 
100008642(ITGA6)
TUP: 
102500081(ITGA6)
CFA: 
100856563(ITGA6)
AML: 
100474079(ITGA6)
UMR: 
103659892(ITGA6)
FCA: 
101092454(ITGA6)
PTG: 
102963994(ITGA6)
BTA: 
535043(ITGA6)
BOM: 
102265941(ITGA6)
PHD: 
102338717(ITGA6)
CHX: 
102186530(ITGA6)
OAS: 
101113656(ITGA6)
SSC: 
100158200(ITGA6)
CFR: 
102518543(ITGA6)
BACU: 
103017654(ITGA6)
LVE: 
103078101(ITGA6)
ECB: 
100064056(ITGA6)
MYB: 
102261916(ITGA6)
MYD: 
102771141(ITGA6)
PALE: 
102883425(ITGA6)
LAV: 
100661035(ITGA6)
MDO: 
100018376(ITGA6)
SHR: 
100929219(ITGA6)
OAA: 
100084141(ITGA6)
GGA: 
396226(ITGA6)
MGP: 
100538428(ITGA6)
CJO: 
107316693(ITGA6)
APLA: 
101791104(ITGA6)
TGU: 
100221694(ITGA6)
GFR: 
102042715(ITGA6)
FAB: 
101812515(ITGA6)
PHI: 
102101887(ITGA6)
CCW: 
104693875(ITGA6)
FPG: 
101924838(ITGA6)
FCH: 
102050643(ITGA6)
CLV: 
102098455(ITGA6)
AAM: 
106499243(ITGA6)
ASN: 
102384271(ITGA6)
AMJ: 
102565962(ITGA6)
PSS: 
102463367(ITGA6)
CMY: 
102942520(ITGA6)
ACS: 
100555687(itga6)
PBI: 
103053454(ITGA6)
GJA: 
107107039(ITGA6)
XTR: 
100497992(itga6)
DRE: 
503893(itga6a) 541320(itga6b)
TRU: 
TNG: 
MZE: 
OLA: 
XMA: 
SASA: 
LCM: 
102345625(ITGA6)
CMK: 
CIN: 
SKO: 
HRO: 
CRG: 
OBI: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1976638
  Authors
Tamura RN, Rozzo C, Starr L, Chambers J, Reichardt LF, Cooper HM, Quaranta V
  Title
Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4.
  Journal
J Cell Biol 111:1593-604 (1990)
  Sequence
[hsa:3655]
Reference
  Authors
Pawar SC, Demetriou MC, Nagle RB, Bowden GT, Cress AE
  Title
Integrin alpha6 cleavage: a novel modification to modulate cell migration.
  Journal
Exp Cell Res 313:1080-9 (2007)

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