KEGG   ORTHOLOGY: K06527Help
Entry
K06527                      KO                                     

Name
VCAM1, CD106
Definition
vascular cell adhesion molecule 1
Pathway
NF-kappa B signaling pathway
Cell adhesion molecules (CAMs)
TNF signaling pathway
Leukocyte transendothelial migration
AGE-RAGE signaling pathway in diabetic complications
African trypanosomiasis
Malaria
HTLV-I infection
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K06527  VCAM1, CD106; vascular cell adhesion molecule 1
   04668 TNF signaling pathway
    K06527  VCAM1, CD106; vascular cell adhesion molecule 1
  Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    K06527  VCAM1, CD106; vascular cell adhesion molecule 1
 Organismal Systems
  Immune system
   04670 Leukocyte transendothelial migration
    K06527  VCAM1, CD106; vascular cell adhesion molecule 1
 Human Diseases
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K06527  VCAM1, CD106; vascular cell adhesion molecule 1
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    K06527  VCAM1, CD106; vascular cell adhesion molecule 1
  Infectious diseases
   05166 HTLV-I infection
    K06527  VCAM1, CD106; vascular cell adhesion molecule 1
   05144 Malaria
    K06527  VCAM1, CD106; vascular cell adhesion molecule 1
   05143 African trypanosomiasis
    K06527  VCAM1, CD106; vascular cell adhesion molecule 1
Cell adhesion molecules and their ligands [BR:ko04516]
 2. Integrin Family
  Beta1 integrins
   VLA-4
    ITGB1; integrin beta 1
     K06527 VCAM1, CD106; vascular cell adhesion molecule 1
   VLA-9
    ITGB1; integrin beta 1
     K06527 VCAM1, CD106; vascular cell adhesion molecule 1
  Beta2 integrins
   CR3, Mac-1
    ITGB2; integrin beta 2
     K06527 VCAM1, CD106; vascular cell adhesion molecule 1
   alpha D beta 2
    ITGB2; integrin beta 2
     K06527 VCAM1, CD106; vascular cell adhesion molecule 1
  Beta7 integrins
   alpha 4 beta 7
    ITGB7; integrin beta 7
     K06527 VCAM1, CD106; vascular cell adhesion molecule 1
CD molecules [BR:ko04090]
 Proteins
  K06527  CD106, VCAM1; vascular cell adhesion molecule 1
Lectins [BR:ko04091]
 I-type lectins (Siglecs)
  K06527  VCAM1, CD106; vascular cell adhesion molecule 1
BRITE hierarchy
Genes
HSA: 
7412(VCAM1)
PTR: 
457059(VCAM1)
PPS: 
100992007(VCAM1)
GGO: 
101152201(VCAM1)
PON: 
100173168(VCAM1)
NLE: 
100584229(VCAM1)
MCC: 
712036(VCAM1)
MCF: 
102131307(VCAM1)
CSAB: 
103224362(VCAM1)
RRO: 
104673258(VCAM1)
RBB: 
108524178(VCAM1)
CJC: 
100385357(VCAM1)
SBQ: 
101043977(VCAM1)
MMU: 
22329(Vcam1)
RNO: 
25361(Vcam1)
CGE: 
100761508(Vcam1)
NGI: 
103741872(Vcam1)
HGL: 
101725534(Vcam1)
CCAN: 
109679450(Vcam1)
OCU: 
100008901(VCAM1)
TUP: 
102492852(VCAM1)
CFA: 
403982(VCAM1)
AML: 
100480380(VCAM1)
UMR: 
103669326(VCAM1)
ORO: 
101370513(VCAM1)
FCA: 
101088865(VCAM1)
PTG: 
102959523(VCAM1)
AJU: 
106976416(VCAM1)
BTA: 
282118(VCAM1) 534578
BOM: 
BIU: 
PHD: 
CHX: 
OAS: 
SSC: 
396925(VCAM1)
CFR: 
102517976(VCAM1)
CDK: 
105084935(VCAM1)
BACU: 
103002158(VCAM1)
LVE: 
103088428(VCAM1)
ECB: 
100050252(VCAM1)
EPZ: 
103550058(VCAM1)
EAI: 
106837775(VCAM1)
MYB: 
102250275(VCAM1)
MYD: 
102754525(VCAM1)
HAI: 
109371359(VCAM1)
RSS: 
109455474(VCAM1)
PALE: 
102883248(VCAM1)
LAV: 
100658668(VCAM1)
TMU: 
MDO: 
100032965(VCAM1)
SHR: 
100916035(VCAM1)
OAA: 
100091415(VCAM1)
GGA: 
424467(VCAM1)
MGP: 
104912281(VCAM1)
CJO: 
107317567(VCAM1)
APLA: 
101791924(VCAM1)
ACYG: 
106039464(VCAM1)
TGU: 
100232188(VCAM1)
GFR: 
102035627(VCAM1)
FAB: 
101820418(VCAM1)
PHI: 
102105359(VCAM1)
PMAJ: 
107208318(VCAM1)
CCW: 
104695379(VCAM1)
FPG: 
101912327(VCAM1)
FCH: 
102055973(VCAM1)
CLV: 
102085253(VCAM1)
EGZ: 
104134033(VCAM1)
AAM: 
106499671(VCAM1)
ASN: 
102367985(VCAM1)
AMJ: 
102570029(VCAM1)
PSS: 
102463382(VCAM1)
CMY: 
102932443(VCAM1)
CPIC: 
101946601(VCAM1)
ACS: 
100558208(vcam1)
PVT: 
110076519(VCAM1)
PBI: 
103050517(VCAM1)
GJA: 
107112245(VCAM1)
XLA: 
108713547(vcam1.L) 108715690(vcam1.S)
XTR: 
100488612(vcam1)
NPR: 
108791458(VCAM1)
DRE: 
561971(vcam1b)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
108271287(vcam1)
AMEX: 
TRU: 
TNG: 
LCO: 
104936354(vcam1)
MZE: 
101480166(vcam1)
OLA: 
101156567(vcam1)
XMA: 
PRET: 
103463162(vcam1)
CSEM: 
103399048(vcam1)
LCF: 
108874150(vcam1)
HCQ: 
109506802(vcam1)
BPEC: 
110166732(vcam1)
SASA: 
ELS: 
SFM: 
LCM: 
102359775(VCAM1)
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2688898
  Authors
Osborn L, Hession C, Tizard R, Vassallo C, Luhowskyj S, Chi-Rosso G, Lobb R
  Title
Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes.
  Journal
Cell 59:1203-11 (1989)
DOI:10.1016/0092-8674(89)90775-7
  Sequence
[hsa:7412]
Reference
  Authors
Braun M, Pietsch P, Schror K, Baumann G, Felix SB
  Title
Cellular adhesion molecules on vascular smooth muscle cells.
  Journal
Cardiovasc Res 41:395-401 (1999)
DOI:10.1016/S0008-6363(98)00302-2

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