KEGG   ORTHOLOGY: K06590Help
Entry
K06590                      KO                                     
Name
ITGB7
Definition
integrin beta 7
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Cell adhesion molecules (CAMs)
Intestinal immune network for IgA production
Regulation of actin cytoskeleton
Transcriptional misregulation in cancer
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K06590  ITGB7; integrin beta 7
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06590  ITGB7; integrin beta 7
   04514 Cell adhesion molecules (CAMs)
    K06590  ITGB7; integrin beta 7
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06590  ITGB7; integrin beta 7
  Cell communication
   04510 Focal adhesion
    K06590  ITGB7; integrin beta 7
 Organismal Systems
  Immune system
   04672 Intestinal immune network for IgA production
    K06590  ITGB7; integrin beta 7
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    K06590  ITGB7; integrin beta 7
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K06590  ITGB7; integrin beta 7
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06590  ITGB7; integrin beta 7
   05414 Dilated cardiomyopathy (DCM)
    K06590  ITGB7; integrin beta 7
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Others
   VCAM1; vascular cell adhesion molecule 1
    alpha 4 beta7
     K06590 ITGB7; integrin beta 7
   MADCAM1; mucosal vascular addressin cell adhesion molecule 1
    alpha 4 beta7
     K06590 ITGB7; integrin beta 7
 5. Cadherin Family
  Classic Cadherins
   Vertebrate Type I classic cadherins
    CDHE, CDH1; cadherin 1, type 1, E-cadherin
     alpha E beta 7
      K06590 ITGB7; integrin beta 7
BRITE hierarchy
Genes
HSA: 
3695(ITGB7)
PTR: 
451934(ITGB7)
PPS: 
100989804(ITGB7)
GGO: 
101145271(ITGB7)
PON: 
100440010(ITGB7)
MCC: 
699405(ITGB7)
MMU: 
16421(Itgb7)
RNO: 
25713(Itgb7)
CFA: 
477598(ITGB7)
AML: 
100474212(ITGB7)
FCA: 
101099982(ITGB7)
BTA: 
514031(ITGB7)
SSC: 
100626600(ITGB7)
ECB: 
100063747(ITGB7)
SHR: 
100920489(ITGB7)
ACS: 
100566599(itgb7)
XTR: 
100486332(itgb7)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
van der Flier A, Sonnenberg A.
  Title
Function and interactions of integrins.
  Journal
Cell Tissue Res 305:285-98 (2001)
Reference
  Authors
Barczyk M, Carracedo S, Gullberg D
  Title
Integrins.
  Journal
Cell Tissue Res 339:269-80 (2010)
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