KEGG   ORTHOLOGY: K06626Help
Entry
K06626                      KO                                     

Name
CCNE
Definition
cyclin E
Pathway
Cell cycle
Oocyte meiosis
p53 signaling pathway
PI3K-Akt signaling pathway
Hippo signaling pathway - fly
Hepatitis B
Measles
Pathways in cancer
Viral carcinogenesis
MicroRNAs in cancer
Prostate cancer
Small cell lung cancer
Module
M00692  
Cell cycle - G1/S transition
Disease
H00018  
Gastric cancer
H00055  
Laryngeal cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04391 Hippo signaling pathway -fly
    K06626  CCNE; cyclin E
   04151 PI3K-Akt signaling pathway
    K06626  CCNE; cyclin E
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K06626  CCNE; cyclin E
   04114 Oocyte meiosis
    K06626  CCNE; cyclin E
   04115 p53 signaling pathway
    K06626  CCNE; cyclin E
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K06626  CCNE; cyclin E
   05206 MicroRNAs in cancer
    K06626  CCNE; cyclin E
   05203 Viral carcinogenesis
    K06626  CCNE; cyclin E
   05215 Prostate cancer
    K06626  CCNE; cyclin E
   05222 Small cell lung cancer
    K06626  CCNE; cyclin E
  Infectious diseases
   05162 Measles
    K06626  CCNE; cyclin E
   05161 Hepatitis B
    K06626  CCNE; cyclin E
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00692  Cell cycle - G1/S transition
     K06626  CCNE; cyclin E
DNA replication proteins [BR:ko03032]
 Eukaryotic Type
  DNA Replication Initiation Factors
   CDK (cyclin dependent kinase)
    K06626  CCNE; cyclin E
Chromosome [BR:ko03036]
 Eukaryotic Type
  Centrosomal proteins
   Cyclins
    K06626  CCNE; cyclin E
BRITE hierarchy
Genes
HSA: 
898(CCNE1) 9134(CCNE2)
PTR: 
455914(CCNE1) 464292(CCNE2)
PPS: 
100972365(CCNE1) 100982783(CCNE2)
GGO: 
101134470(CCNE1) 101153263(CCNE2)
PON: 
100438282(CCNE2) 100461587(CCNE1)
NLE: 
100602200(CCNE2) 100607751(CCNE1)
MCC: 
700382 700589(CCNE1)
MCF: 
102137714(CCNE1) 102138564(CCNE2)
CJC: 
100396520(CCNE1) 100403750(CCNE2)
MMU: 
12447(Ccne1) 12448(Ccne2)
RNO: 
25729(Ccne1) 362485(Ccne2)
CGE: 
100753358(Ccne1) 100760464(Ccne2)
NGI: 
103740830(Ccne1) 103745830(Ccne2)
HGL: 
101701725(Ccne2) 101711961(Ccne1)
OCU: 
100134864(CCNE1) 100134867(CCNE2)
TUP: 
102468317(CCNE1) 102492088(CCNE2)
CFA: 
484610(CCNE1) 487057(CCNE2)
AML: 
UMR: 
103661328(CCNE1) 103661444(CCNE2)
FCA: 
101085347(CCNE2) 101086192(CCNE1)
PTG: 
102955833(CCNE2) 102966425(CCNE1)
BTA: 
533526(CCNE1) 538436(CCNE2)
BOM: 
102271261(CCNE1) 102284697(CCNE2)
PHD: 
102329453(CCNE1) 102331117(CCNE2)
CHX: 
102184185(CCNE1) 102185672(CCNE2)
OAS: 
101107124(CCNE1) 101109811(CCNE2)
SSC: 
100512048(CCNE2) 100523248(CCNE1)
CFR: 
102512815(CCNE2) 102516466(CCNE1)
BACU: 
102997538(CCNE2) 103008660(CCNE1)
LVE: 
103078168(CCNE1) 103087546(CCNE2)
ECB: 
100053882(CCNE1) 100055302(CCNE2)
MYB: 
102244734(CCNE1) 102248984(CCNE2)
MYD: 
102763547(CCNE2) 102769827(CCNE1)
PALE: 
102882260(CCNE1) 102882411(CCNE2)
MDO: 
100014623(CCNE1) 100022654(CCNE2)
SHR: 
100920942(CCNE1) 100924454(CCNE2)
OAA: 
100075784(CCNE2) 100087197(CCNE1)
GGA: 
420231(CCNE2) 426117(CCNE1)
MGP: 
APLA: 
101792020(CCNE2) 101792902(CCNE1)
TGU: 
100220841(CCNE1) 100222121(CCNE2)
FAB: 
101809310(CCNE2) 101821269(CCNE1)
PHI: 
102111744(CCNE2) 102114128(CCNE1)
FPG: 
101913703(CCNE2) 101923204(CCNE1)
FCH: 
102047310(CCNE2) 102059423(CCNE1)
CLV: 
102091343(CCNE1) 102094830(CCNE2)
ASN: 
102368597(CCNE2) 102382034(CCNE1)
AMJ: 
102568414(CCNE2) 102569019(CCNE1)
PSS: 
102445271(CCNE2) 102460990(CCNE1)
CMY: 
102931864(CCNE2) 102941488(CCNE1)
ACS: 
100553527(ccne1) 100563792(ccne2)
PBI: 
103052775(CCNE1) 103066008(CCNE2)
XLA: 
380219(ccne2) 397840(cycE1) 397841(ccne1) 495419
XTR: 
549021(ccne2) 549082(ccne1)
DRE: 
30188(ccne1) 415165(ccne2)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102363290(CCNE2) 102366176(CCNE1)
CMK: 
103175366(ccne2) 103176046(ccne1)
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
411327(CycE)
NVI: 
100114765(cycE)
TCA: 
BMOR: 
100216493(Cyce)
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG12774(Cbr-cye-1)
HRO: 
LGI: 
NVE: 
HMG: 
TAD: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Jeon Y, Lee KY, Ko MJ, Lee YS, Kang S, Hwang DS
  Title
Human TopBP1 participates in cyclin E/CDK2 activation and preinitiation complex assembly during G1/S transition.
  Journal
J Biol Chem 282:14882-90 (2007)
  Sequence
[hsa:898]
Reference
  Authors
Ferguson RL, Maller JL
  Title
Cyclin E-dependent localization of MCM5 regulates centrosome duplication.
  Journal
J Cell Sci 121:3224-32 (2008)
  Sequence
[hsa:898]
Reference
  Authors
Moberg KH, Bell DW, Wahrer DC, Haber DA, Hariharan IK
  Title
Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines.
  Journal
Nature 413:311-6 (2001)
  Sequence

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