KEGG   ORTHOLOGY: K06645Help
Entry
K06645                      KO                                     

Name
CDC25A
Definition
M-phase inducer phosphatase 1 [EC:3.1.3.48]
Pathway
Cell cycle
Progesterone-mediated oocyte maturation
MicroRNAs in cancer
Module
M00691  
DNA damage-induced cell cycle checkpoints
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K06645  CDC25A; M-phase inducer phosphatase 1
 Organismal Systems
  Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K06645  CDC25A; M-phase inducer phosphatase 1
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    K06645  CDC25A; M-phase inducer phosphatase 1
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00691  DNA damage-induced cell cycle checkpoints
     K06645  CDC25A; M-phase inducer phosphatase 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     K06645  CDC25A; M-phase inducer phosphatase 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Tyrosine phosphatases (PTPs)
  Class III PTPs
   CDC25s
    K06645  CDC25A; M-phase inducer phosphatase 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
993(CDC25A)
PTR: 
460341(CDC25A)
PPS: 
100985899(CDC25A)
GGO: 
101142222(CDC25A)
PON: 
100460228(CDC25A)
NLE: 
100588003(CDC25A)
MCC: 
710858(CDC25A)
MCF: 
102137696(CDC25A)
CJC: 
100408832(CDC25A)
MMU: 
12530(Cdc25a)
RNO: 
171102(Cdc25a)
CGE: 
100767961(Cdc25a)
NGI: 
103750230(Cdc25a)
HGL: 
101699133(Cdc25a)
OCU: 
100354280(CDC25A)
TUP: 
102482369(CDC25A)
CFA: 
484780(CDC25A)
AML: 
100477247(CDC25A)
UMR: 
103675112(CDC25A)
FCA: 
101098445(CDC25A)
PTG: 
102957057(CDC25A)
BTA: 
520188(CDC25A)
BOM: 
102285046(CDC25A)
PHD: 
102326574(CDC25A)
CHX: 
102181731(CDC25A)
OAS: 
101113178(CDC25A)
SSC: 
CFR: 
102509600(CDC25A)
BACU: 
103016547(CDC25A)
LVE: 
103085456(CDC25A)
ECB: 
100064223(CDC25A)
MYB: 
MYD: 
102760761(CDC25A)
PALE: 
102897196(CDC25A)
MDO: 
100018150(CDC25A)
SHR: 
100924467(CDC25A)
OAA: 
100085311(CDC25A)
GGA: 
420375(CDC25A)
MGP: 
APLA: 
101800901(CDC25A)
TGU: 
100231363(CDC25A)
FAB: 
101816817(CDC25A)
PHI: 
102104005(CDC25A)
FPG: 
101911899(CDC25A)
FCH: 
102054923(CDC25A)
CLV: 
102084553(CDC25A)
ASN: 
102384816(CDC25A)
AMJ: 
102569214(CDC25A)
PSS: 
102458852(CDC25A)
CMY: 
102931776(CDC25A)
ACS: 
PBI: 
XLA: 
398141 734734(cdc25a)
XTR: 
733851(cdc25a)
CIN: 
LGI: 
NVE: 
HMG: 
TAD: 
ACAN: 
GTT: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Karlsson-Rosenthal C, Millar JB
  Title
Cdc25: mechanisms of checkpoint inhibition and recovery.
  Journal
Trends Cell Biol 16:285-92 (2006)
Reference
  Authors
Hong HY, Choi J, Cho YW, Kim BC
  Title
Cdc25A promotes cell survival by stimulating NF-kappaB activity through IkappaB-alpha phosphorylation and destabilization.
  Journal
Biochem Biophys Res Commun 420:293-6 (2012)
  Sequence
[hsa:993]

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