KEGG   ORTHOLOGY: K06704Help
Entry
K06704                      KO                                     

Name
ADAM10
Definition
disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
Pathway
Alzheimer's disease
Epithelial cell signaling in Helicobacter pylori infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K06704  ADAM10; disintegrin and metalloproteinase domain-containing protein 10
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K06704  ADAM10; disintegrin and metalloproteinase domain-containing protein 10
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.81  ADAM10 endopeptidase
     K06704  ADAM10; disintegrin and metalloproteinase domain-containing protein 10
Peptidases [BR:ko01002]
 Metallo Peptidases
  Family M12: astacin/adamalysin family
   K06704  ADAM10; disintegrin and metalloproteinase domain-containing protein 10
Cellular antigens [BR:ko04090]
 Proteins
  K06704  CD156c, ADAM10; a disintegrin and metalloproteinase domain 10
BRITE hierarchy
Genes
HSA: 
102(ADAM10)
PTR: 
746942(ADAM10)
PPS: 
100979438(ADAM10)
GGO: 
101142970(ADAM10)
PON: 
100169741(ADAM10)
NLE: 
100606667(ADAM10)
MCC: 
701355(ADAM10)
MCF: 
101925715(ADAM10)
RRO: 
104670896(ADAM10)
CJC: 
100415138(ADAM10)
MMU: 
11487(Adam10)
RNO: 
29650(Adam10)
CGE: 
100772891(Adam10)
NGI: 
103737147(Adam10)
HGL: 
101698280(Adam10)
OCU: 
100101614(ADAM10)
TUP: 
102467957(ADAM10)
CFA: 
478321(ADAM10)
AML: 
100476350(ADAM10)
UMR: 
103676794(ADAM10)
FCA: 
101087998(ADAM10)
PTG: 
102950285(ADAM10)
BTA: 
282132(ADAM10)
BOM: 
102285401(ADAM10)
PHD: 
102324691(ADAM10)
CHX: 
102172903(ADAM10)
OAS: 
101116733(ADAM10)
SSC: 
397345(ADAM10)
CFR: 
102518129(ADAM10)
BACU: 
103011557(ADAM10)
LVE: 
103071850(ADAM10)
ECB: 
100068314(ADAM10)
MYB: 
102260183(ADAM10)
MYD: 
102754258(ADAM10)
PALE: 
102895434(ADAM10)
MDO: 
SHR: 
OAA: 
100074755(ADAM10)
GGA: 
374113(ADAM10)
MGP: 
APLA: 
101794215(ADAM10)
TGU: 
100219653(ADAM10)
GFR: 
102043060(ADAM10)
FAB: 
101811782(ADAM10)
PHI: 
102110765(ADAM10)
CCW: 
104684038(ADAM10)
FPG: 
101910860(ADAM10)
FCH: 
102050786(ADAM10)
CLV: 
102083444(ADAM10)
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
100553674(adam10)
PBI: 
XLA: 
399187(adam10)
XTR: 
733451(adam10)
DRE: 
393392(adam10b) 560975(ADAMLc) 566044(adam10a)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DWI: 
DYA: 
Dyak_GE18670(dyak_GLEANR_2455) Dyak_GE23876(dyak_GLEANR_7624)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
TCA: 
BMOR: 
PXY: 
API: 
PHU: 
ISC: 
CEL: 
CELE_DY3.7(sup-17)
CBR: 
CBG12369(Cbr-sup-17)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
MBR: 
SRE: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9305925
  Authors
Rosendahl MS, Ko SC, Long DL, Brewer MT, Rosenzweig B, Hedl E, Anderson L, Pyle SM, Moreland J, Meyers MA, Kohno T, Lyons D, Lichenstein HS
  Title
Identification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases.
  Journal
J Biol Chem 272:24588-93 (1997)
  Sequence
[hsa:102]
Reference
  Authors
Vincent B, Paitel E, Saftig P, Frobert Y, Hartmann D, De Strooper B, Grassi J, Lopez-Perez E, Checler F
  Title
The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein.
  Journal
J Biol Chem 276:37743-6 (2001)
  Sequence
[hsa:102]

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