KEGG   ORTHOLOGY: K06751Help
Entry
K06751                      KO                                     

Name
MHC1
Definition
major histocompatibility complex, class I
Pathway
Endocytosis
Phagosome
Cell adhesion molecules (CAMs)
Antigen processing and presentation
Natural killer cell mediated cytotoxicity
Type I diabetes mellitus
HTLV-I infection
Herpes simplex infection
Epstein-Barr virus infection
Viral carcinogenesis
Autoimmune thyroid disease
Allograft rejection
Graft-versus-host disease
Viral myocarditis
Disease
H00344  
Leprosy
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    K06751  MHC1; major histocompatibility complex, class I
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K06751  MHC1; major histocompatibility complex, class I
   04145 Phagosome
    K06751  MHC1; major histocompatibility complex, class I
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K06751  MHC1; major histocompatibility complex, class I
   04612 Antigen processing and presentation
    K06751  MHC1; major histocompatibility complex, class I
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K06751  MHC1; major histocompatibility complex, class I
  Immune diseases
   05320 Autoimmune thyroid disease
    K06751  MHC1; major histocompatibility complex, class I
   05330 Allograft rejection
    K06751  MHC1; major histocompatibility complex, class I
   05332 Graft-versus-host disease
    K06751  MHC1; major histocompatibility complex, class I
  Cardiovascular diseases
   05416 Viral myocarditis
    K06751  MHC1; major histocompatibility complex, class I
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K06751  MHC1; major histocompatibility complex, class I
  Infectious diseases
   05166 HTLV-I infection
    K06751  MHC1; major histocompatibility complex, class I
   05168 Herpes simplex infection
    K06751  MHC1; major histocompatibility complex, class I
   05169 Epstein-Barr virus infection
    K06751  MHC1; major histocompatibility complex, class I
Exosome [BR:ko04147]
 Exosomal proteins
  Proteins found in most exosomes
   K06751  MHC1; major histocompatibility complex, class I
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Immune system
   Others
    CD8A; CD8A antigen, alpha polypeptide
     K06751 MHC1; major histocompatibility complex, class I
    CD8B; CD8B antigen, beta polypeptide 1
     K06751 MHC1; major histocompatibility complex, class I
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
3105(HLA-A) 3106(HLA-B) 3107(HLA-C) 3133(HLA-E) 3134(HLA-F) 3135(HLA-G)
PTR: 
100169977(PATR-F) 450151(PATR-A) 450202(PATR-B) 462540(PATR-E) 463178(PATR-AL) 471962(PATR-C) 494187(PATR-G) 749652
PPS: 
GGO: 
PON: 
MCC: 
100141394(MAMU-B18) 694372 699243(MAMU-A3) 700391(MAMU-B) 709076(MAMU-F) 711532(MAMU-E) 711832(MAMU-A) 714964 715737 719483 720132 720372(MAMU-I) 722711 723284 723473 723552
MCF: 
102117143(Mafa-A) 102122138(Mafa-F) 102123548 102125623(Mafa-A) 102138874(MHC-E) 102138883(Mafa-B)
MMU: 
101056305 110557(H2-Q6) 110696(H2-M10.3) 14963(H2-Bl) 14964(H2-D1) 14972(H2-K1) 14985(H2-M10.1) 14990(H2-M2) 14991(H2-M3) 14997(H2-M9) 15006(H2-Q1) 15007(H2-Q10) 15013(H2-Q2) 15018(H2-Q7) 15019(H2-Q8) 15024(H2-T10) 15039(H2-T22) 15040(H2-T23) 15042(H2-T24) 15043(H2-T3) 15051(H2-T9) 224753(H2-M10.4) 224754(H2-M11) 224756(H2-M1) 224761(H2-M10.5) 333715(H2-M10.2) 399549(H2-M10.6) 547349
RNO: 
100188935(Rt1.aa) 24737(RT1-EC2) 24747(RT1-M3-1) 24748(RT1-N1) 24750(RT1-N3) 24751(RT1-O1) 24973(RT1-A1) 24974(RT1-A2) 24977(RT1-Cl) 24988(RT1-M2) 294213(RT1-M1-4) 294228(RT1-S3) 309584(RT1-M4) 309600(RT1-CE12) 309603(RT1-CE1) 309607(RT1-CE5) 309627(RT1-A3) 360323(RT1-N2) 361787(RT1-T24-1) 365527(RT1-M6-2) 368153(RT1-CE7) 406194(RT1-T18) 414270(RT1-CE14) 414779(RT1-CE2) 414783(RT1-CE4) 414784(RT1-T24-4) 414785(RT1-M6-1) 414786(RT1-M1-2) 414787(RT1-M10-1) 414788(RT1-T24-3) 414789(RT1-CE15) 414790(RT1-CE13) 414791(RT1-CE11) 414792(RT1-CE10) 414793(RT1-CE3) 414819(RT1-CE16) 680842(RT1-M1-5)
CGE: 
HGL: 
TUP: 
CFA: 
474836(DLA88) 474838(DLA-64) 483594(DLA-79)
AML: 
FCA: 
BTA: 
100126048(BOLA-N) 407173(JSP.1) 509006 512672 515712(BOLA) 767904 782684(BOLA-A)
BOM: 
PHD: 
CHX: 
SSC: 
100037288(SLA-3) 100037293(SLA-1) 100135029(SLA-5) 100135031(SLA-2) 100135036(SLA-8) 100135037(SLA-6) 100626428 396650(SLA-7)
CFR: 
ECB: 
MYB: 
MDO: 
100024719 100026156(MODO-UM) 100026178(MODO-UE) 100026665(MODO-UJ) 100026781(MODO-UI) 100026802 100026822(MODO-UK) 751097(MHC-1) 790902(MODO-UB)
SHR: 
100913535(SAHAI-01) 100919863(SAHAI-12) 100928906
OAA: 
GGA: 
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
ASN: 
PSS: 
ACS: 
XLA: 
100126623 373808(mhc1a-a) 379561(hla-a) 398628
XTR: 
DRE: 
393557(mhc1uxa2) 64885(mhc1uea)
TRU: 
MZE: 
OLA: 
100125825(orla-uaa) 101166971(orla-uba) 101167218(orla-uaa) 101174157(orla-uga)
XMA: 
LCM: 
102360671(Lach-UA-02)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Belicha-Villanueva A, Blickwedehl J, McEvoy S, Golding M, Gollnick SO, Bangia N
  Title
What is the role of alternate splicing in antigen presentation by major histocompatibility complex class I molecules?
  Journal
Immunol Res 46:32-44 (2010)
Reference
  Authors
Donaldson JG, Porat-Shliom N, Cohen LA
  Title
Clathrin-independent endocytosis: a unique platform for cell signaling and PM remodeling.
  Journal
Cell Signal 21:1-6 (2009)

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