KEGG   ORTHOLOGY: K07210Help
Entry
K07210                      KO                                     

Name
IKBKG, IKKG, NEMO
Definition
inhibitor of nuclear factor kappa-B kinase subunit gamma
Pathway
MAPK signaling pathway
Ras signaling pathway
Chemokine signaling pathway
NF-kappa B signaling pathway
PI3K-Akt signaling pathway
Apoptosis
Osteoclast differentiation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Cytosolic DNA-sensing pathway
T cell receptor signaling pathway
B cell receptor signaling pathway
TNF signaling pathway
Adipocytokine signaling pathway
Epithelial cell signaling in Helicobacter pylori infection
Shigellosis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Hepatitis C
Hepatitis B
HTLV-I infection
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Pancreatic cancer
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Primary immunodeficiency
Module
M00686  
Toll-like receptor signaling
Disease
H00095  
Ectodermal dysplasia associated immunodeficiency (EDA-ID)
H00540  
Osteoporosis, lymphedema, anhydrotic ectodermal dysplasia with immunodeficiency (OLEDAID)
H00645  
Incontinentia pigmenti
H01245  
Immunodeficiency without anhidrotic ectodermal  dysplasia
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04010 MAPK signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04064 NF-kappa B signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04668 TNF signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04151 PI3K-Akt signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04621 NOD-like receptor signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04622 RIG-I-like receptor signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04623 Cytosolic DNA-sensing pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04660 T cell receptor signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04662 B cell receptor signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04062 Chemokine signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  Endocrine system
   04920 Adipocytokine signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  Development
   04380 Osteoclast differentiation
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05203 Viral carcinogenesis
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05212 Pancreatic cancer
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05221 Acute myeloid leukemia
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05220 Chronic myeloid leukemia
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05215 Prostate cancer
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05222 Small cell lung cancer
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  Immune diseases
   05340 Primary immunodeficiency
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05131 Shigellosis
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05166 HTLV-I infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05161 Hepatitis B
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05160 Hepatitis C
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05168 Herpes simplex infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05169 Epstein-Barr virus infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05145 Toxoplasmosis
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05142 Chagas disease (American trypanosomiasis)
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00686  Toll-like receptor signaling
     K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: Other group
  IKK family [OT]
   K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
BRITE hierarchy
Genes
HSA: 
8517(IKBKG)
PTR: 
PPS: 
100987483(IKBKG)
GGO: 
PON: 
100449496(IKBKG)
NLE: 
MCC: 
701237(IKBKG)
MCF: 
102115368(IKBKG)
CJC: 
100390258(IKBKG)
MMU: 
16151(Ikbkg)
RNO: 
309295(Ikbkg)
CGE: 
100759762(Ikbkg)
NGI: 
103731232(Ikbkg)
HGL: 
101712077(Ikbkg)
OCU: 
100328905(IKBKG)
TUP: 
CFA: 
612576(IKBKG)
AML: 
100470223(IKBKG)
UMR: 
103679680(IKBKG)
FCA: 
101086544(IKBKG)
PTG: 
102967956(IKBKG)
BTA: 
281855(IKBKG)
BOM: 
102287968(IKBKG)
PHD: 
102321023(IKBKG)
CHX: 
102171591(IKBKG)
OAS: 
101107332(IKBKG)
SSC: 
100127355(IKBKG)
CFR: 
BACU: 
LVE: 
103074882(IKBKG)
ECB: 
100058432(IKBKG)
MYB: 
102252013(IKBKG)
MYD: 
102772051(IKBKG)
PALE: 
MDO: 
100022918(IKBKG)
SHR: 
100926701(IKBKG)
OAA: 
100073613(IKBKG)
PHI: 
102113899(IKBKG)
ASN: 
102374662(IKBKG)
AMJ: 
102561500(IKBKG)
PSS: 
102445093(IKBKG)
CMY: 
102938812(IKBKG)
ACS: 
100567119(ikbkg)
PBI: 
103053675(IKBKG)
XLA: 
735069(ikbkg)
XTR: 
100145270(ikbkg)
DRE: 
541530(ikbkg)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102351908(IKBKG)
BFO: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Solt LA, May MJ
  Title
The IkappaB kinase complex: master regulator of NF-kappaB signaling.
  Journal
Immunol Res 42:3-18 (2008)

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