KEGG   ORTHOLOGY: K07293Help
Entry
K07293                      KO                                     

Name
PTPN11
Definition
tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
Pathway
MAPK signaling pathway - fly
Ras signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Adipocytokine signaling pathway
Epithelial cell signaling in Helicobacter pylori infection
Herpes simplex infection
Proteoglycans in cancer
Renal cell carcinoma
Chronic myeloid leukemia
Disease
H00523  
Noonan syndrome and related disorders
H01018  
Metachondromatosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
   04013 MAPK signaling pathway - fly
    K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
   04630 Jak-STAT signaling pathway
    K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
   04670 Leukocyte transendothelial migration
    K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
  Endocrine system
   04920 Adipocytokine signaling pathway
    K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
  Nervous system
   04722 Neurotrophin signaling pathway
    K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
   05220 Chronic myeloid leukemia
    K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
   05211 Renal cell carcinoma
    K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
   05168 Herpes simplex infection
    K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5781(PTPN11)
PTR: 
467135(PTPN11) 748225(PTPN11)
PPS: 
100970556(PTPN11)
GGO: 
101133729(PTPN11)
PON: 
100440983(PTPN11)
MCC: 
712044(PTPN11)
MCF: 
102129572(PTPN11)
MMU: 
19247(Ptpn11)
RNO: 
25622(Ptpn11)
CGE: 
100771077(Ptpn11)
HGL: 
101701336(Ptpn11)
TUP: 
102485136(PTPN11)
CFA: 
477488(PTPN11)
AML: 
100468867(PTPN11)
FCA: 
PTG: 
BTA: 
526769 533590(PTPN11)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
CFR: 
BACU: 
LVE: 
103088783(PTPN11)
ECB: 
MYB: 
102251345(PTPN11)
MYD: 
102755861(PTPN11)
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
395815(PTPN11) 419429
MGP: 
TGU: 
100218949(PTPN11)
FAB: 
101811730(PTPN11)
PHI: 
102103197(PTPN11)
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
399291(ptpn11) 444193
XTR: 
548434 549586(ptpn11)
DRE: 
333979(ptpn11a) 393426(ptpn11b)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
Dvir_GJ16938(Dvir_csw)
AGA: 
AAG: 
CQU: 
AME: 
412529(csw)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CBR: 
CBG02539(Cbr-ptp-2)
BMY: 
LOA: 
TSP: 
SMM: 
HMG: 
AQU: 
MBR: 
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Jakob S, Schroeder P, Lukosz M, Buchner N, Spyridopoulos I, Altschmied J, Haendeler J
  Title
Nuclear protein tyrosine phosphatase Shp-2 is one important negative regulator of nuclear export of telomerase reverse transcriptase.
  Journal
J Biol Chem 283:33155-61 (2008)

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