KEGG   ORTHOLOGY: K07360Help
Entry
K07360                      KO                                     
Name
ZAP70
Definition
tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
Pathway
NF-kappa B signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
Primary immunodeficiency
Disease
H00093  
Combined immunodeficiencies (CIDs)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
   04660 T cell receptor signaling pathway
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
 Human Diseases
  Immune diseases
   05340 Primary immunodeficiency
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     K07360  ZAP70; tyrosine-protein kinase ZAP-70
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  Syk family
   K07360  ZAP70; tyrosine-protein kinase ZAP-70
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
7535(ZAP70)
PTR: 
459427(ZAP70)
PPS: 
100971372(ZAP70)
GGO: 
101139136(ZAP70)
PON: 
100451782(ZAP70)
MCC: 
707555(ZAP70)
MMU: 
22637(Zap70)
RNO: 
301348(Zap70)
CFA: 
100271860(ZAP70)
AML: 
FCA: 
101097059(ZAP70)
BTA: 
504509(ZAP70)
SSC: 
100739325
ECB: 
100147296
MDO: 
100025187(ZAP70)
SHR: 
100916187(ZAP70)
OAA: 
100084852(ZAP70)
GGA: 
420086(ZAP70)
MGP: 
100542877(ZAP70)
TGU: 
100229988(ZAP70)
XLA: 
446840(zap70)
XTR: 
448557(zap70)
DRE: 
553615(zap70)
TRU: 
101069105
OLA: 
101170171
NVE: 
NEMVE_v1g194745
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Bradshaw JM
  Title
The Src, Syk, and Tec family kinases: distinct types of molecular switches.
  Journal
Cell Signal 22:1175-84 (2010)
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