KEGG   ORTHOLOGY: K07412Help
Entry
K07412                      KO                                     

Name
CYP2B
Definition
cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
Pathway
Steroid hormone biosynthesis
Arachidonic acid metabolism
Retinol metabolism
Metabolic pathways
Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
   00590 Arachidonic acid metabolism
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07412  CYP2B; cytochrome P450 family 2 subfamily B
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K07412  CYP2B; cytochrome P450 family 2 subfamily B
BRITE hierarchy
Other DBs
Genes
MMU: 
13088(Cyp2b10) 13089(Cyp2b13) 13090(Cyp2b19) 13094(Cyp2b9) 243881(Cyp2b23)
RNO: 
108348266 24300(Cyp2b1) 286953(Cyp2b3) 292728(Cyp2b21) 29295(Cyp2b12) 361523(Cyp2b2) 685222(Cyp2b15)
CGE: 
NGI: 
HGL: 
CCAN: 
OCU: 
TUP: 
CFA: 
474177(CYP2B6)
AML: 
UMR: 
ORO: 
FCA: 
PTG: 
AJU: 
BTA: 
504769(CYP2B6) 530571
BOM: 
BIU: 
PHD: 
CHX: 
OAS: 
SSC: 
102165015 403104(CYP2B22)
CFR: 
CDK: 
ECB: 
EPZ: 
EAI: 
MYB: 
MYD: 
HAI: 
RSS: 
LAV: 
TMU: 
MDO: 
SHR: 
ASN: 
AMJ: 
CMY: 
MYI: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:6306654
  Authors
Mizukami Y, Sogawa K, Suwa Y, Muramatsu M, Fujii-Kuriyama Y
  Title
Gene structure of a phenobarbital-inducible cytochrome P-450 in rat liver.
  Journal
Proc Natl Acad Sci U S A 80:3958-62 (1983)
DOI:10.1073/pnas.80.13.3958
  Sequence
[rno:361523]
Reference
  Authors
Sun H, Lee CM, Tripathi S, Kim KB, Morgan ET
  Title
Nitric oxide-dependent CYP2B degradation is potentiated by a cytokine-regulated pathway and utilizes the immunoproteasome subunit LMP2.
  Journal
Biochem J 445:377-82 (2012)
DOI:10.1042/BJ20120820

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