KEGG   ORTHOLOGY: K07412Help
Entry
K07412                      KO                                     

Name
CYP2B
Definition
cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
Pathway
ko00140  Steroid hormone biosynthesis
ko00590  Arachidonic acid metabolism
ko00830  Retinol metabolism
ko01100  Metabolic pathways
ko05204  Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
   00590 Arachidonic acid metabolism
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07412  CYP2B; cytochrome P450 family 2 subfamily B
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K07412  CYP2B; cytochrome P450 family 2 subfamily B
BRITE hierarchy
Other DBs
RN: R03408 R07001 R07048 R07050 R07051 R07052 R08390 R08391 R08392
Genes
MMU: 13088(Cyp2b10) 13089(Cyp2b13) 13090(Cyp2b19) 13094(Cyp2b9) 243881(Cyp2b23)
RNO: 108348266 24300(Cyp2b1) 286953(Cyp2b3) 292728(Cyp2b21) 29295(Cyp2b12) 361523(Cyp2b2) 685222(Cyp2b15)
CGE: 100759787 100760248 100762876 100763166 100763642 100763652 100765152 100765441 107977085
NGI: 103734439 103734444 103734445 103734446 103751524
HGL: 101700457 101711936 101712634 101713256 101716410
CCAN: 109680168 109703253
OCU: 100327257(CYP2B4) 100328947(CYP2B5) 100328948 100353574 100359087
TUP: 102479421 102494535
CFA: 474177(CYP2B6)
AML: 100464347 100471209
PTG: 102958471
BTA: 504769(CYP2B6) 530571
SSC: 102165015 403104(CYP2B22)
MYD: 102751643
RSS: 109458115
MDO: 100018927
SHR: 100931571
ASN: 102369937
AMJ: 102571887
CMY: 102947273
MYI: 110455337
 » show all
TaxonomyKoalaUniProt
Reference
PMID:6306654
  Authors
Mizukami Y, Sogawa K, Suwa Y, Muramatsu M, Fujii-Kuriyama Y
  Title
Gene structure of a phenobarbital-inducible cytochrome P-450 in rat liver.
  Journal
Proc Natl Acad Sci U S A 80:3958-62 (1983)
DOI:10.1073/pnas.80.13.3958
  Sequence
[rno:361523]
Reference
  Authors
Sun H, Lee CM, Tripathi S, Kim KB, Morgan ET
  Title
Nitric oxide-dependent CYP2B degradation is potentiated by a cytokine-regulated pathway and utilizes the immunoproteasome subunit LMP2.
  Journal
Biochem J 445:377-82 (2012)
DOI:10.1042/BJ20120820

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