KEGG ORTHOLOGY: K07412

ORTHOLOGY: K07412

Entry

K07412 KO

Name

CYP2B

Definition

cytochrome P450, family 2, subfamily B [EC:1.14.14.1]

Pathway

ko00590	Arachidonic acid metabolism
ko00830	Retinol metabolism
ko00980	Metabolism of xenobiotics by cytochrome P450
ko00982	Drug metabolism - cytochrome P450
ko05204	Chemical carcinogenesis

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Lipid metabolism
   00590 Arachidonic acid metabolism
    K07412  CYP2B; cytochrome P450, family 2, subfamily B
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07412  CYP2B; cytochrome P450, family 2, subfamily B
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K07412  CYP2B; cytochrome P450, family 2, subfamily B
   00982 Drug metabolism - cytochrome P450
    K07412  CYP2B; cytochrome P450, family 2, subfamily B
Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    K07412  CYP2B; cytochrome P450, family 2, subfamily B
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07412  CYP2B; cytochrome P450, family 2, subfamily B
Cytochrome P450 [BR:ko00199]
Cytochrome P450, animal type
  CYP2 family
   CYP2B subfamily
    K07412  CYP2B; cytochrome P450, family 2, subfamily B

Other DBs

RN:

R07000 R07001 R07021 R07022 R07048 R07050 R07051 R07052 R07066 R07068 R07098 R07099 R07107 R08275 R08285 R08286 R08287 R08313 R08324 R08325 R08326 R08390 R08391 R08392 R09441

Genes

HSA:	1555(CYP2B6)
PTR:	456052
PPS:	100984180
GGO:	101151678
PON:	100457779 100458142
MCC:	678687(CYP2B6)
MMU:	13088(Cyp2b10) 13089(Cyp2b13) 13090(Cyp2b19) 13094(Cyp2b9) 243881(Cyp2b23)
RNO:	100909962 24300(Cyp2b1) 286953(Cyp2b3) 292728(Cyp2b21) 29295(Cyp2b12) 361523(Cyp2b2)
CFA:	474177(CYP2B6)
AML:	100464347 100471209
BTA:	504769(CYP2B6) 530571
SSC:	403104(CYP2B22)
ECB:	100068569
MDO:	100018927
SHR:	100931571
ACS:	100552139

» show all

Reference

PMID:21116621

Authors

Kirischian N, McArthur AG, Jesuthasan C, Krattenmacher B, Wilson JY

Title

Phylogenetic and functional analysis of the vertebrate cytochrome p450 2 family.

Journal

J Mol Evol 72:56-71 (2011)

All links

Ontology (6)   
   KEGG BRITE (6)   
Pathway (12)   
   KEGG PATHWAY (12)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (47)   
   KEGG ENZYME (1)   
   KEGG REACTION (25)   
   KEGG RCLASS (21)   
Gene (35)   
   KEGG GENES (28)   
   KEGG EGENES (7)   
Protein sequence (18)   
   UniProt (18)   
Literature (1)   
   PubMed (1)   
All databases (120)   

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