KEGG   ORTHOLOGY: K07415Help
Entry
K07415                      KO                                     

Name
CYP2E1
Definition
cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
Pathway
Steroid hormone biosynthesis
Arachidonic acid metabolism
Linoleic acid metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Non-alcoholic fatty liver disease (NAFLD)
Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07415  CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1
   00590 Arachidonic acid metabolism
    K07415  CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1
   00591 Linoleic acid metabolism
    K07415  CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K07415  CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1
   00982 Drug metabolism - cytochrome P450
    K07415  CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    K07415  CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K07415  CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.-  
     K07415  CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K07415  CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1
BRITE hierarchy
Other DBs
Genes
HSA: 
1571(CYP2E1)
PTR: 
450857(CYP2E1)
PPS: 
GGO: 
PON: 
100173813(CYP2E1)
NLE: 
MCC: 
678688(CYP2E1)
MCF: 
CSAB: 
103245979(CYP2E1)
RRO: 
CJC: 
100397922(CYP2E1)
SBQ: 
MMU: 
13106(Cyp2e1)
RNO: 
25086(Cyp2e1)
CGE: 
NGI: 
HGL: 
OCU: 
TUP: 
CFA: 
415128(CYP2E1)
AML: 
UMR: 
FCA: 
554227(CYP2E2) 554344(CYP2E1)
PTG: 
AJU: 
BTA: 
282213(CYP2E1)
BOM: 
PHD: 
CHX: 
OAS: 
100568285(CYP2E1)
SSC: 
403216(CYP2E1)
CFR: 
BACU: 
LVE: 
ECB: 
100066422(CYP2E1)
MYB: 
MYD: 
HAI: 
109383522(CYP2E1)
MDO: 
SHR: 
OAA: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3782137
  Authors
Song BJ, Gelboin HV, Park SS, Yang CS, Gonzalez FJ
  Title
Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme.
  Journal
J Biol Chem 261:16689-97 (1986)
  Sequence
[hsa:1571]

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