KEGG   ORTHOLOGY: K07424Help
Entry
K07424                      KO                                     
Name
CYP3A
Definition
cytochrome P450, family 3, subfamily A [EC:1.14.14.1]
Pathway
Steroid hormone biosynthesis
Linoleic acid metabolism
Aminobenzoate degradation
Retinol metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Drug metabolism - other enzymes
Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07424  CYP3A; cytochrome P450, family 3, subfamily A
   00591 Linoleic acid metabolism
    K07424  CYP3A; cytochrome P450, family 3, subfamily A
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07424  CYP3A; cytochrome P450, family 3, subfamily A
  Xenobiotics biodegradation and metabolism
   00627 Aminobenzoate degradation
    K07424  CYP3A; cytochrome P450, family 3, subfamily A
   00980 Metabolism of xenobiotics by cytochrome P450
    K07424  CYP3A; cytochrome P450, family 3, subfamily A
   00982 Drug metabolism - cytochrome P450
    K07424  CYP3A; cytochrome P450, family 3, subfamily A
   00983 Drug metabolism - other enzymes
    K07424  CYP3A; cytochrome P450, family 3, subfamily A
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    K07424  CYP3A; cytochrome P450, family 3, subfamily A
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07424  CYP3A; cytochrome P450, family 3, subfamily A
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP3 family
   CYP3A subfamily
    K07424  CYP3A; cytochrome P450, family 3, subfamily A
BRITE hierarchy
Other DBs
Genes
HSA: 
1551(CYP3A7) 1576(CYP3A4) 1577(CYP3A5) 64816(CYP3A43)
PTR: 
100608616 463582(CYP3A4) 472456(CYP3A43) 737263(CYP3A7) 737374(CYP3A5)
PPS: 
GGO: 
PON: 
MCC: 
100144394(CYP3A7) 678670(CYP3A4) 678692(CYP3A5) 709770(CYP3A43)
MMU: 
100041375(Cyp3a41b) 13112(Cyp3a11) 13113(Cyp3a13) 13114(Cyp3a16) 337924(Cyp3a44) 53973(Cyp3a41a) 56388(Cyp3a25)
RNO: 
100910877 171352(Cyp3a9) 252931(Cyp3a18) 25642(Cyp3a23/3a1) 266682(Cyp3a2)
CFA: 
415129(CYP3A12) 479740(CYP3A4)
AML: 
FCA: 
100642187(CYP3A132) 100652377(CYP3A131)
BTA: 
282214(CYP3A5) 507988(CYP3A4) 526682(CYP3A5)
SSC: 
100126281(CYP3A46) 100144468(CYP3A22) 403322(CYP3A39) 403324(CYP3A29)
ECB: 
100067041(CYP3A93) 100067064(CYP3A89) 100067084(CYP3A94) 100067109(CYP3A95)
MDO: 
100010745 100010783 100010820 100013114 100013238
SHR: 
100918011
OAA: 
100082218 100082250 100091970
GGA: 
414832(CYP3A7) 416477(CYP3A4)
MGP: 
678668(CYP3A80) 678669(CYP3A37)
TGU: 
100226034
ACS: 
100555955 100557851
XLA: 
100037189(cyp3a4) 398964 495363(cyp3a5)
XTR: 
100487054 100487665 548503(cyp3a4)
DRE: 
553969(cyp3a65)
TRU: 
101069124
OLA: 
100125817(cyp3a40)
BFO: 
BRAFLDRAFT_201702
CIN: 
100169892 100182809 100187173
SPU: 
578821 579059 581116
AGA: 
AgaP_AGAP000818 AgaP_AGAP012294 AgaP_AGAP012295(CYP9L1) AgaP_AGAP012296
CQU: 
CpipJ_CPIJ010175 CpipJ_CPIJ010539 CpipJ_CPIJ010541 CpipJ_CPIJ010544 CpipJ_CPIJ012470
AME: 
409677(Cyp6as5) 412209(CYP6AS4)
CBR: 
CBG01027(Cbr-cyp-13A6) CBG01302
NVE: 
NEMVE_v1g142057
TAD: 
TRIADDRAFT_13664
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
McArthur AG, Hegelund T, Cox RL, Stegeman JJ, Liljenberg M, Olsson U, Sundberg P, Celander MC
  Title
Phylogenetic analysis of the cytochrome P450 3 (CYP3) gene family.
  Journal
J Mol Evol 57:200-11 (2003)
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