KEGG   ORTHOLOGY: K07425Help
Entry
K07425                      KO                                     

Name
CYP4A
Definition
alkane 1-monooxygenase [EC:1.14.15.3]
Pathway
Fatty acid degradation
Arachidonic acid metabolism
Retinol metabolism
PPAR signaling pathway
Vascular smooth muscle contraction
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00071 Fatty acid degradation
    K07425  CYP4A; alkane 1-monooxygenase
   00590 Arachidonic acid metabolism
    K07425  CYP4A; alkane 1-monooxygenase
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07425  CYP4A; alkane 1-monooxygenase
 Organismal Systems
  Endocrine system
   03320 PPAR signaling pathway
    K07425  CYP4A; alkane 1-monooxygenase
  Circulatory system
   04270 Vascular smooth muscle contraction
    K07425  CYP4A; alkane 1-monooxygenase
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K07425  CYP4A; alkane 1-monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.3  alkane 1-monooxygenase
     K07425  CYP4A; alkane 1-monooxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP4 family
   K07425  CYP4A; alkane 1-monooxygenase
BRITE hierarchy
Other DBs
Genes
PTR: 
PON: 
MMU: 
100040843(Cyp4a32) 13117(Cyp4a10) 13118(Cyp4a12b) 13119(Cyp4a14) 230639(Cyp4a29) 277753(Cyp4a12a) 435802(Cyp4a30b) 666168(Cyp4a31)
RNO: 
24306(Cyp4a2) 266674(Cyp4a8) 298423(Cyp4a3) 50549(Cyp4a1)
CGE: 
CFA: 
475366(CYP4A38) 482506(CYP4A37)
AML: 
BTA: 
516085(CYP4A22)
SSC: 
100522145 403326(CYP4A24)
MDO: 
TaxonomyKoalaUniProt
Reference
  Authors
Hsu MH, Savas U, Griffin KJ, Johnson EF
  Title
Human cytochrome p450 family 4 enzymes: function, genetic variation and regulation.
  Journal
Drug Metab Rev 39:515-38 (2007)

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