KEGG   ORTHOLOGY: K07431Help
Entry
K07431                      KO                                     

Name
CYP8B1
Definition
sterol 12-alpha-hydroxylase [EC:1.14.13.95 1.14.13.96]
Pathway
Primary bile acid biosynthesis
PPAR signaling pathway
Module
M00104  
Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00120 Primary bile acid biosynthesis
    K07431  CYP8B1; sterol 12-alpha-hydroxylase
 Organismal Systems
  Endocrine system
   03320 PPAR signaling pathway
    K07431  CYP8B1; sterol 12-alpha-hydroxylase
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Sterol biosynthesis
    M00104  Bile acid biosynthesis, cholesterol => cholate
     K07431  CYP8B1; sterol 12-alpha-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.95  7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase
     K07431  CYP8B1; sterol 12-alpha-hydroxylase
    1.14.13.96  5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase
     K07431  CYP8B1; sterol 12-alpha-hydroxylase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP8 family
   K07431  CYP8B1; sterol 12-alpha-hydroxylase
BRITE hierarchy
Other DBs
RN: 
GO: 
Genes
HSA: 
1582(CYP8B1)
PTR: 
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
MCF: 
CJC: 
100402181(CYP8B1)
MMU: 
13124(Cyp8b1)
RNO: 
81924(Cyp8b1)
CGE: 
NGI: 
OCU: 
100009301(CYP8B1)
TUP: 
CFA: 
AML: 
UMR: 
FCA: 
PTG: 
BTA: 
538964(CYP8B1)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
403328(CYP8B1)
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
100026549(CYP8B)
SHR: 
OAA: 
GGA: 
425055(CYP8B1)
MGP: 
APLA: 
TGU: 
FAB: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
379482(cyp8b1)
XTR: 
DRE: 
445281(cyp8b1)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
UMA: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Russell DW
  Title
The enzymes, regulation, and genetics of bile acid synthesis.
  Journal
Annu Rev Biochem 72:137-74 (2003)
  Sequence
[hsa:1582] [mmu:13124]

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