KEGG   ORTHOLOGY: K07434Help
Entry
K07434                      KO                                     
Name
CYP19A
Definition
cytochrome P450, family 19, subfamily A [EC:1.14.14.1]
Pathway
Steroid hormone biosynthesis
Ovarian steroidogenesis
Module
M00110  
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
Disease
H00599  
46,XX disorders of sex development (Disorders related to androgen excess)
H00794  
Aromatase excess syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07434  CYP19A; cytochrome P450, family 19, subfamily A
 Organismal Systems
  Endocrine system
   04913 Ovarian Steroidogenesis
    K07434  CYP19A; cytochrome P450, family 19, subfamily A
KEGG pathway modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Sterol biosynthesis
    M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
     K07434  CYP19A; cytochrome P450, family 19, subfamily A
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07434  CYP19A; cytochrome P450, family 19, subfamily A
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP19 family
   CYP19A subfamily
    K07434  CYP19A; cytochrome P450, family 19, subfamily A
BRITE hierarchy
Other DBs
Genes
HSA: 
1588(CYP19A1)
PTR: 
453433(CYP19A1)
PPS: 
GGO: 
PON: 
MCC: 
678697(CYP19A1)
MMU: 
13075(Cyp19a1)
RNO: 
25147(Cyp19a1)
CFA: 
494003(CYP19A1)
AML: 
FCA: 
101094932(CYP19A1)
BTA: 
281740(CYP19A1)
SSC: 
403331(CYP19A1) 403333(CYP19A3)
ECB: 
100009712(CYP19A1)
MDO: 
100031295
SHR: 
100929873
OAA: 
100078619
GGA: 
414854(CYP19A1)
MGP: 
100549427
TGU: 
751777(CYP19A1)
ACS: 
100565397(cyp19a1)
XLA: 
373656(cyp19a1)
XTR: 
100036594(cyp19a1)
DRE: 
30390(cyp19a1a) 60640(cyp19a1b)
TRU: 
101076508(pfCYP19A)
OLA: 
100125815(cyp19b) 101174651(Aromatase)
BFO: 
BRAFLDRAFT_247066
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Mouriec K, Lareyre JJ, Tong SK, Le Page Y, Vaillant C, Pellegrini E, Pakdel F, Chung BC, Kah O, Anglade I
  Title
Early regulation of brain aromatase (cyp19a1b) by estrogen receptors during zebrafish development.
  Journal
Dev Dyn 238:2641-51 (2009)
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