KEGG   ORTHOLOGY: K07434Help
Entry
K07434                      KO                                     

Name
CYP19A
Definition
aromatase [EC:1.14.14.14]
Pathway
ko00140  Steroid hormone biosynthesis
ko01100  Metabolic pathways
ko04913  Ovarian steroidogenesis
Module
M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
Disease
H00599  46,XX disorders of sex development (Disorders related to androgen excess)
H00794  Aromatase excess syndrome
H02020  Aromatase deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07434  CYP19A; aromatase
 Organismal Systems
  Endocrine system
   04913 Ovarian Steroidogenesis
    K07434  CYP19A; aromatase
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Sterol biosynthesis
    M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
     K07434  CYP19A; aromatase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.14  aromatase
     K07434  CYP19A; aromatase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP19 family
   K07434  CYP19A; aromatase
BRITE hierarchy
Other DBs
RN: R01840 R02351 R02501 R03087 R04759 R04761
Genes
HSA: 1588(CYP19A1)
PTR: 453433(CYP19A1)
PPS: 100984744
GGO: 101137192
PON: 100439777
NLE: 100589061
MCC: 678697(CYP19A1)
MCF: 102117886(CYP19)
CSAB: 103245629(CYP19A1)
RRO: 104656901
RBB: 108544828
CJC: 100411557(CYP19A1)
SBQ: 101051393
MMU: 13075(Cyp19a1)
RNO: 25147(Cyp19a1)
CGE: 100769024
NGI: 103731396
OCU: 100328545(CYP19A1)
TUP: 102503106
CFA: 494003(CYP19A1)
AML: 100464417
UMR: 103676745
ORO: 101383271
FCA: 101094932
PTG: 102962141
AJU: 106967273
BTA: 281740(CYP19A1)
BOM: 102277416
BIU: 109565118
PHD: 102343465
CHX: 100861413(CYP19A1) 102172726
OAS: 100144423(CYP19)
SSC: 403331(CYP19A1) 403332(CYP19A2) 403333(CYP19A3)
CFR: 102519005
ECB: 100009712(CYP19A1)
EPZ: 103546924
EAI: 106838329
MYB: 102253564
MYD: 102753728
HAI: 109394298
RSS: 109446840
PALE: 102884354
LAV: 100669426
TMU: 101350058
MDO: 100031295
SHR: 100929873
OAA: 100078619
GGA: 414854(CYP19A1)
MGP: 100549427
CJO: 107318718(CYP19)
APLA: 101791068
ACYG: 106033779
TGU: 751777(CYP19A1)
GFR: 102039345
FAB: 101821137
PHI: 102100785
CCW: 104684007
FPG: 101920378
FCH: 102056433
CLV: 102090413
EGZ: 104130907
AAM: 106496434
ASN: 102378511
AMJ: 102566432(CYP19A1)
PSS: 102459111
CMY: 102946653
CPIC: 101943325(aromatase)
ACS: 100565397(cyp19a1)
PVT: 110077216
PBI: 103056596
GJA: 107122388
XLA: 373656(cyp19a1.L)
XTR: 100036594(cyp19a1)
NPR: 108799589
DRE: 30390(cyp19a1a) 60640(cyp19a1b)
IPU: 100304581 108264511(CYPXIX)
TRU: 100379639(pfcyp19b-tstr) 101076508(pfcyp19a)
LCO: 104920192(CYP19a) 104932825(CYP19b)
OLA: 100125815(cyp19b) 101174651
SASA: 106562534 106584746(CYP19B) 106587170(CYP19)
SFM: 108942040
LCM: 102348763
CMK: 103186779
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2973313
  Authors
Harada N
  Title
Cloning of a complete cDNA encoding human aromatase: immunochemical identification and sequence analysis.
  Journal
Biochem Biophys Res Commun 156:725-32 (1988)
DOI:10.1016/S0006-291X(88)80903-3
  Sequence
[hsa:1588]

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