KEGG   ORTHOLOGY: K07828Help
Entry
K07828                      KO                                     
Name
NRAS
Definition
GTPase NRas
Pathway
MAPK signaling pathway
ErbB signaling pathway
Chemokine signaling pathway
PI3K-Akt signaling pathway
Axon guidance
VEGF signaling pathway
Tight junction
Gap junction
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Long-term potentiation
Neurotrophin signaling pathway
Cholinergic synapse
Serotonergic synapse
Long-term depression
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Prolactin signaling pathway
Alcoholism
Hepatitis C
Hepatitis B
HTLV-I infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Thyroid cancer
Melanoma
Bladder cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Disease
H00003  
Acute myeloid leukemia (AML)
H00010  
Multiple myeloma
H00016  
Oral cancer
H00032  
Thyroid cancer
H00033  
Adrenal carcinoma
H00038  
Malignant melanoma
H00048  
Hepatocellular carcinoma
H00108  
Autoimmune lymphoproliferative syndromes (ALPS)
H00523  
Noonan syndrome and related disorders
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K07828  NRAS; GTPase NRas
   04012 ErbB signaling pathway
    K07828  NRAS; GTPase NRas
   04370 VEGF signaling pathway
    K07828  NRAS; GTPase NRas
   04151 PI3K-Akt signaling pathway
    K07828  NRAS; GTPase NRas
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K07828  NRAS; GTPase NRas
  Cell communication
   04530 Tight junction
    K07828  NRAS; GTPase NRas
   04540 Gap junction
    K07828  NRAS; GTPase NRas
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K07828  NRAS; GTPase NRas
   04660 T cell receptor signaling pathway
    K07828  NRAS; GTPase NRas
   04662 B cell receptor signaling pathway
    K07828  NRAS; GTPase NRas
   04664 Fc epsilon RI signaling pathway
    K07828  NRAS; GTPase NRas
   04062 Chemokine signaling pathway
    K07828  NRAS; GTPase NRas
  Endocrine system
   04910 Insulin signaling pathway
    K07828  NRAS; GTPase NRas
   04912 GnRH signaling pathway
    K07828  NRAS; GTPase NRas
   04915 Estrogen signaling pathway
    K07828  NRAS; GTPase NRas
   04917 Prolactin signaling pathway
    K07828  NRAS; GTPase NRas
   04916 Melanogenesis
    K07828  NRAS; GTPase NRas
  Nervous system
   04725 Cholinergic synapse
    K07828  NRAS; GTPase NRas
   04726 Serotonergic synapse
    K07828  NRAS; GTPase NRas
   04720 Long-term potentiation
    K07828  NRAS; GTPase NRas
   04730 Long-term depression
    K07828  NRAS; GTPase NRas
   04722 Neurotrophin signaling pathway
    K07828  NRAS; GTPase NRas
  Development
   04360 Axon guidance
    K07828  NRAS; GTPase NRas
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K07828  NRAS; GTPase NRas
   05205 Proteoglycans in cancer
    K07828  NRAS; GTPase NRas
   05203 Viral carcinogenesis
    K07828  NRAS; GTPase NRas
   05214 Glioma
    K07828  NRAS; GTPase NRas
   05216 Thyroid cancer
    K07828  NRAS; GTPase NRas
   05221 Acute myeloid leukemia
    K07828  NRAS; GTPase NRas
   05220 Chronic myeloid leukemia
    K07828  NRAS; GTPase NRas
   05218 Melanoma
    K07828  NRAS; GTPase NRas
   05211 Renal cell carcinoma
    K07828  NRAS; GTPase NRas
   05219 Bladder cancer
    K07828  NRAS; GTPase NRas
   05215 Prostate cancer
    K07828  NRAS; GTPase NRas
   05213 Endometrial cancer
    K07828  NRAS; GTPase NRas
   05223 Non-small cell lung cancer
    K07828  NRAS; GTPase NRas
  Substance dependence
   05034 Alcoholism
    K07828  NRAS; GTPase NRas
  Infectious diseases
   05166 HTLV-I infection
    K07828  NRAS; GTPase NRas
   05161 Hepatitis B
    K07828  NRAS; GTPase NRas
   05160 Hepatitis C
    K07828  NRAS; GTPase NRas
GTP-binding proteins [BR:ko04031]
 Small (Monomeric) G-proteins
  Ras Family
   Ras [Table]
    K07828  NRAS; GTPase NRas
BRITE hierarchy
Genes
HSA: 
4893(NRAS)
PTR: 
742713(NRAS)
PPS: 
100970465(NRAS)
PON: 
100174317(NRAS)
MCC: 
709089(NRAS)
MMU: 
18176(Nras)
RNO: 
24605(Nras)
CFA: 
403872(NRAS)
AML: 
FCA: 
751105(N-RAS)
BTA: 
506322(NRAS)
SSC: 
100739349(NRAS)
ECB: 
100059469
MDO: 
554197(NRAS)
GGA: 
419885(NRAS)
TGU: 
100222058(NRAS)
ACS: 
100565176
XLA: 
399446(n-ras)
XTR: 
549517
DRE: 
30380(nras)
BFO: 
BRAFLDRAFT_271363 BRAFLDRAFT_62308
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Colicelli J
  Title
Human RAS superfamily proteins and related GTPases.
  Journal
Sci STKE 2004:RE13 (2004)
Reference
  Authors
Wolfman A
  Title
Ras isoform-specific signaling: location, location, location.
  Journal
Sci STKE 2001:pe2 (2001)
Reference
  Authors
Olson MF, Marais R
  Title
Ras protein signalling.
  Journal
Semin Immunol 12:63-73 (2000)
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