KEGG   ORTHOLOGY: K07860Help
Entry
K07860                      KO                                     
Name
RAC2
Definition
Ras-related C3 botulinum toxin substrate 2
Pathway
MAPK signaling pathway
Chemokine signaling pathway
Wnt signaling pathway
Axon guidance
VEGF signaling pathway
Focal adhesion
Adherens junction
Natural killer cell mediated cytotoxicity
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Regulation of actin cytoskeleton
Pathways in cancer
Colorectal cancer
Pancreatic cancer
Viral myocarditis
Disease
H00099  
Leukocyte adhesion deficiency (LAD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
   04310 Wnt signaling pathway
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
   04370 VEGF signaling pathway
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
  Cell communication
   04510 Focal adhesion
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
   04520 Adherens junction
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
   04662 B cell receptor signaling pathway
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
   04664 Fc epsilon RI signaling pathway
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
   04666 Fc gamma R-mediated phagocytosis
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
   04670 Leukocyte transendothelial migration
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
   04062 Chemokine signaling pathway
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
  Development
   04360 Axon guidance
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
   05210 Colorectal cancer
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
   05212 Pancreatic cancer
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
  Cardiovascular diseases
   05416 Viral myocarditis
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
GTP-binding proteins [BR:ko04031]
 Small (Monomeric) G-proteins
  Rho Family
   Rac/Cdc42
    K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
BRITE hierarchy
Genes
HSA: 
5880(RAC2)
PTR: 
742575(RAC2)
PPS: 
100993959(RAC2)
GGO: 
101141534(RAC2)
PON: 
100431483(RAC2)
MCC: 
696709(RAC2)
MMU: 
19354(Rac2)
RNO: 
366957(Rac2)
CFA: 
481271(RAC2)
AML: 
FCA: 
101096744(RAC2)
BTA: 
327671(RAC2)
SSC: 
100621675
ECB: 
100054701
MDO: 
100017517
SHR: 
100932383(RAC2)
OAA: 
100092844
GGA: 
418044(RAC2)
MGP: 
100547045
TGU: 
100230090(RAC2)
ACS: 
100557692
XLA: 
444184(rac2)
XTR: 
496738(rac2)
DRE: 
415151(rac2)
TRU: 
101071607
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Burridge K, Wennerberg K.
  Title
Rho and Rac take center stage.
  Journal
Cell 116:167-79 (2004)
Reference
  Authors
Takai Y, Sasaki T, Matozaki T.
  Title
Small GTP-binding proteins.
  Journal
Physiol Rev 81:153-208 (2001)
Reference
  Authors
Wennerberg K, Der CJ.
  Title
Rho-family GTPases: it's not only Rac and Rho (and I like it).
  Journal
J Cell Sci 117:1301-12 (2004)
DBGET integrated database retrieval system