KEGG   ORTHOLOGY: K08008Help
Entry
K08008                      KO                                     

Name
NOX, MOX1
Definition
NADPH oxidase 1
Pathway
HIF-1 signaling pathway
Phagosome
Osteoclast differentiation
NOD-like receptor signaling pathway
Leukocyte transendothelial migration
AGE-RAGE signaling pathway in diabetic complications
Fluid shear stress and atherosclerosis
Disease
H00098  
Chronic granulomatous disease
H01167  
Gluconobacter infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    K08008  NOX, MOX1; NADPH oxidase 1
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K08008  NOX, MOX1; NADPH oxidase 1
 Organismal Systems
  Immune system
   04621 NOD-like receptor signaling pathway
    K08008  NOX, MOX1; NADPH oxidase 1
   04670 Leukocyte transendothelial migration
    K08008  NOX, MOX1; NADPH oxidase 1
  Development
   04380 Osteoclast differentiation
    K08008  NOX, MOX1; NADPH oxidase 1
 Human Diseases
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K08008  NOX, MOX1; NADPH oxidase 1
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    K08008  NOX, MOX1; NADPH oxidase 1
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   NADPH oxidase complex
    K08008  NOX, GP91; NADPH oxidase
BRITE hierarchy
Other DBs
Genes
HSA: 
27035(NOX1)
PTR: 
465752(NOX1)
PPS: 
100987167(NOX1)
GGO: 
101129463(NOX1)
PON: 
100447193(NOX1)
NLE: 
100591259(NOX1)
MCC: 
701376(NOX1)
MCF: 
102116010(NOX1)
CSAB: 
103232344(NOX1)
RRO: 
104675589(NOX1)
CJC: 
100403058(NOX1)
SBQ: 
101037120(NOX1)
MMU: 
237038(Nox1)
RNO: 
114243(Nox1)
CGE: 
100770704(Nox1)
NGI: 
103746208(Nox1)
HGL: 
101718925(Nox1)
OCU: 
100008852(NOX1)
TUP: 
102470131(NOX1)
CFA: 
492016(NOX1)
AML: 
100470141(NOX1)
UMR: 
103672992(NOX1)
FCA: 
101086376(NOX1)
PTG: 
102971358(NOX1)
AJU: 
106983528(NOX1)
BTA: 
521681(NOX1)
BOM: 
102282195(NOX1)
PHD: 
102320552(NOX1)
CHX: 
102178048(NOX1)
OAS: 
100034667(NOX1)
SSC: 
100739747(NOX1) 100739822(NOX1)
CFR: 
102514861(NOX1)
BACU: 
103009515(NOX1)
LVE: 
103087970(NOX1)
ECB: 
100146916(NOX1)
MYB: 
102251611(NOX1)
MYD: 
102773376(NOX1)
HAI: 
109373133(NOX1)
PALE: 
102880187(NOX1)
GGA: 
422257(NOX1)
MGP: 
100538688(NOX1)
CJO: 
107312742(NOX1)
APLA: 
101798310(NOX1)
TGU: 
100229711(NOX1)
GFR: 
102033670(NOX1)
FAB: 
101811141(NOX1)
PHI: 
102109968(NOX1)
CCW: 
104691363(NOX1)
FPG: 
101923736(NOX1)
FCH: 
102052248(NOX1)
CLV: 
102096707(NOX1)
AAM: 
106484775(NOX1)
ASN: 
102378223(NOX1)
AMJ: 
102563592(NOX1)
PSS: 
102449099(NOX1)
CMY: 
102943351(NOX1)
CPIC: 
101947647(NOX1)
PBI: 
103061033(NOX1)
GJA: 
107124542(NOX1)
XLA: 
XTR: 
100495329(nox1)
DRE: 
555604(nox1)
IPU: 
108268853(nox1)
TRU: 
100125326(nox1)
TNG: 
LCO: 
104928731(nox1)
MZE: 
101474828(nox1)
OLA: 
101164407(nox1)
XMA: 
102226905(nox1)
SASA: 
LCM: 
102366676(NOX1)
CMK: 
103177228(nox1)
NCR: 
NCU02110(nox-1)
NTE: 
NEUTE1DRAFT132521(NEUTE1DRAFT_132521)
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
FPU: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
VDA: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_804154(AO090003000460)
ANG: 
ANI_1_1330074(An08g10000)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
PBN: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
TMS: 
DSQ: 
PCO: 
SHS: 
HIR: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT110182(AGABI1DRAFT_110182)
ABV: 
AGABI2DRAFT189922(AGABI2DRAFT_189922)
CPUT: 
SLA: 
WSE: 
WIC: 
PGR: 
MLR: 
DDI: 
DPP: 
DFA: 
DFA_10391(noxB)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Arakawa N, Katsuyama M, Matsuno K, Urao N, Tabuchi Y, Okigaki M, Matsubara H, Yabe-Nishimura C
  Title
Novel transcripts of Nox1 are regulated by alternative promoters and expressed under phenotypic modulation of vascular smooth muscle cells.
  Journal
Biochem J 398:303-10 (2006)
  Sequence
[mmu:237038]
Reference
  Authors
Ueno N, Takeya R, Miyano K, Kikuchi H, Sumimoto H
  Title
The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent  manner: its regulation by oxidase organizers and activators.
  Journal
J Biol Chem 280:23328-39 (2005)
  Sequence
[hsa:50508]

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