KEGG   ORTHOLOGY: K08009Help
Entry
K08009                      KO                                     

Name
CYBA, P22PHOX
Definition
cytochrome b-245, alpha polypeptide
Pathway
ko04145  Phagosome
ko04380  Osteoclast differentiation
ko04621  NOD-like receptor signaling pathway
ko04670  Leukocyte transendothelial migration
ko05140  Leishmaniasis
ko05418  Fluid shear stress and atherosclerosis
Disease
H00098  Chronic granulomatous disease
H01167  Gluconobacter infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
 Organismal Systems
  Immune system
   04621 NOD-like receptor signaling pathway
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
   04670 Leukocyte transendothelial migration
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
  Development
   04380 Osteoclast differentiation
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
 Human Diseases
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
  Infectious diseases
   05140 Leishmaniasis
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   NADPH oxidase complex
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
BRITE hierarchy
Other DBs
TC: 5.B.1.1.1
Genes
HSA: 1535(CYBA)
PTR: 468068(CYBA)
PPS: 100986914
GGO: 101141497
PON: 100456737
NLE: 100595279
MCC: 696748(CYBA)
MCF: 102143777
CSAB: 103233451
RRO: 104655986
RBB: 108520444
CJC: 100414967(CYBA)
SBQ: 101045425
MMU: 13057(Cyba)
RNO: 79129(Cyba)
CGE: 100766833
NGI: 103740013
HGL: 101717043
CCAN: 109692739
OCU: 100008800(CYBA)
TUP: 102471991
CFA: 489664(CYBA)
AML: 100482979
UMR: 103673846
ORO: 101364731
FCA: 101091745
BTA: 281111(CYBA)
BOM: 102270937
BIU: 109572735
PHD: 102329680
CHX: 102188617
OAS: 101106452
SSC: 397507(CYBA)
CFR: 102509853
CDK: 105104683
BACU: 102999052
LVE: 103090543
OOR: 101274948
ECB: 100049843(CYBA)
EAI: 106828257
MYB: 102242122
MYD: 102760442
HAI: 109389148
RSS: 109453169
PALE: 102885155
LAV: 100666572
TMU: 101355438
MDO: 100026086
SHR: 100932491
OAA: 100084242
GGA: 100859840(CYBA)
MGP: 100544408
CJO: 107319525
TGU: 100230391
GFR: 102036039
FAB: 101819099
PHI: 102100453
PMAJ: 107210059
FPG: 101915504
FCH: 102051514
CLV: 102091746
AAM: 106491416
ASN: 102385608
AMJ: 102558462
PSS: 102449370
CMY: 102946998
CPIC: 101937351
ACS: 100555174
PVT: 110076319
PBI: 103052761
GJA: 107119316
XLA: 108704084(cyba.S) 446853(cyba.L)
XTR: 549234(cyba)
NPR: 108802186
DRE: 393551(cyba)
IPU: 108264585
AMEX: 103041742
TRU: 445889(p22phox)
LCO: 104927415
NCC: 104964892
MZE: 101470167
OLA: 101170577
XMA: 102219145
PRET: 103462573
NFU: 107381322
CSEM: 103379180
LCF: 108877826
HCQ: 109525911
BPEC: 110175258
ELS: 105015958
SFM: 108940834
LCM: 102353925
CMK: 103175997
CIN: 100182370
SPU: 100889590
APLC: 110975693
SKO: 102806390
MYI: 110449899
OBI: 106870690
LAK: 106157842
EPA: 110245830
ADF: 107348189
HMG: 100213059
AQU: 100637130
DDI: DDB_G0267460(cybA)
DFA: DFA_07591(cybA)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Miyano K, Sumimoto H
  Title
Role of the small GTPase Rac in p22phox-dependent NADPH oxidases.
  Journal
Biochimie 89:1133-44 (2007)
DOI:10.1016/j.biochi.2007.05.003
Reference
PMID:3368442
  Authors
Parkos CA, Dinauer MC, Walker LE, Allen RA, Jesaitis AJ, Orkin SH
  Title
Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b.
  Journal
Proc Natl Acad Sci U S A 85:3319-23 (1988)
DOI:10.1073/pnas.85.10.3319
  Sequence
[hsa:1535]

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