KEGG   ORTHOLOGY: K08014Help
Entry
K08014                      KO                                     

Name
RAPGEF3, EPAC1
Definition
Rap guanine nucleotide exchange factor 3
Pathway
Rap1 signaling pathway
cAMP signaling pathway
Adrenergic signaling in cardiomyocytes
Leukocyte transendothelial migration
Long-term potentiation
Serotonergic synapse
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
   04024 cAMP signaling pathway
    K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
 Organismal Systems
  Immune system
   04670 Leukocyte transendothelial migration
    K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
  Nervous system
   04726 Serotonergic synapse
    K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
   04720 Long-term potentiation
    K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
BRITE hierarchy
Genes
HSA: 
10411(RAPGEF3)
PTR: 
467198(RAPGEF3)
PPS: 
100979763(RAPGEF3)
GGO: 
101153785(RAPGEF3)
PON: 
100174087(RAPGEF3)
MCC: 
703967(RAPGEF3)
MCF: 
MMU: 
223864(Rapgef3)
RNO: 
59326(Rapgef3)
CGE: 
100767619(Rapgef3)
HGL: 
101711127(Rapgef3)
TUP: 
102502265(RAPGEF3)
CFA: 
486591(RAPGEF3)
AML: 
100473947(RAPGEF3)
FCA: 
101085387(RAPGEF3)
PTG: 
102966186(RAPGEF3)
BTA: 
535383(RAPGEF3)
BOM: 
102282215(RAPGEF3)
PHD: 
102320480(RAPGEF3)
CHX: 
102178145(RAPGEF3)
SSC: 
100620989(RAPGEF3)
CFR: 
102524040(RAPGEF3)
BACU: 
103005728(RAPGEF3)
LVE: 
103080613(RAPGEF3)
ECB: 
100050541(RAPGEF3)
MYB: 
102257237(RAPGEF3)
MYD: 
102768579(RAPGEF3)
PALE: 
102895678(RAPGEF3)
SHR: 
100925807(RAPGEF3)
GGA: 
426888(RAPGEF3)
FAB: 
101814980(RAPGEF3)
PHI: 
102110109(RAPGEF3)
APLA: 
101791788(RAPGEF3)
FPG: 
101924930(RAPGEF3)
FCH: 
102048878(RAPGEF3)
CLV: 
ASN: 
102381678(RAPGEF3)
AMJ: 
102574517(RAPGEF3)
PSS: 
102443863(RAPGEF3)
CMY: 
ACS: 
100560594(rapgef3)
PBI: 
103063904(RAPGEF3)
XLA: 
733186(rapgef3)
XTR: 
100491495(rapgef3)
DRE: 
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Gloerich M, Bos JL
  Title
Epac: defining a new mechanism for cAMP action.
  Journal
Annu Rev Pharmacol Toxicol 50:355-75 (2010)

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