KEGG   ORTHOLOGY: K08041Help
Entry
K08041                      KO                                     

Name
ADCY1
Definition
adenylate cyclase 1 [EC:4.6.1.1]
Pathway
Purine metabolism
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
Chagas disease (American trypanosomiasis)
Amoebiasis
HTLV-I infection
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K08041  ADCY1; adenylate cyclase 1
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04020 Calcium signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04024 cAMP signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04022 cGMP - PKG signaling pathway
    K08041  ADCY1; adenylate cyclase 1
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K08041  ADCY1; adenylate cyclase 1
  Cellular commiunity
   04540 Gap junction
    K08041  ADCY1; adenylate cyclase 1
 Organismal Systems
  Immune system
   04611 Platelet activation
    K08041  ADCY1; adenylate cyclase 1
   04062 Chemokine signaling pathway
    K08041  ADCY1; adenylate cyclase 1
  Endocrine system
   04911 Insulin secretion
    K08041  ADCY1; adenylate cyclase 1
   04912 GnRH signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04913 Ovarian Steroidogenesis
    K08041  ADCY1; adenylate cyclase 1
   04915 Estrogen signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04914 Progesterone-mediated oocyte maturation
    K08041  ADCY1; adenylate cyclase 1
   04921 Oxytocin signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04918 Thyroid hormone synthesis
    K08041  ADCY1; adenylate cyclase 1
   04916 Melanogenesis
    K08041  ADCY1; adenylate cyclase 1
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08041  ADCY1; adenylate cyclase 1
   04270 Vascular smooth muscle contraction
    K08041  ADCY1; adenylate cyclase 1
  Digestive system
   04970 Salivary secretion
    K08041  ADCY1; adenylate cyclase 1
   04971 Gastric acid secretion
    K08041  ADCY1; adenylate cyclase 1
   04972 Pancreatic secretion
    K08041  ADCY1; adenylate cyclase 1
   04976 Bile secretion
    K08041  ADCY1; adenylate cyclase 1
  Nervous system
   04724 Glutamatergic synapse
    K08041  ADCY1; adenylate cyclase 1
   04727 GABAergic synapse
    K08041  ADCY1; adenylate cyclase 1
   04725 Cholinergic synapse
    K08041  ADCY1; adenylate cyclase 1
   04720 Long-term potentiation
    K08041  ADCY1; adenylate cyclase 1
   04723 Retrograde endocannabinoid signaling
    K08041  ADCY1; adenylate cyclase 1
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K08041  ADCY1; adenylate cyclase 1
  Environmental adaptation
   04713 Circadian entrainment
    K08041  ADCY1; adenylate cyclase 1
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    K08041  ADCY1; adenylate cyclase 1
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K08041  ADCY1; adenylate cyclase 1
  Infectious diseases
   05166 HTLV-I infection
    K08041  ADCY1; adenylate cyclase 1
   05146 Amoebiasis
    K08041  ADCY1; adenylate cyclase 1
   05142 Chagas disease (American trypanosomiasis)
    K08041  ADCY1; adenylate cyclase 1
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08041  ADCY1; adenylate cyclase 1
BRITE hierarchy
Other DBs
Genes
HSA: 
107(ADCY1)
PTR: 
463392(ADCY1)
PPS: 
100984585(ADCY1)
GGO: 
101125943(ADCY1)
PON: 
100449504(ADCY1)
MCC: 
697230(ADCY1)
MCF: 
102147015(ADCY1)
MMU: 
432530(Adcy1)
RNO: 
305509(Adcy1)
CGE: 
100764561(Adcy1)
HGL: 
101711366(Adcy1)
TUP: 
102468873(ADCY1)
CFA: 
607357(ADCY1)
AML: 
FCA: 
101101375(ADCY1)
PTG: 
102961712(ADCY1)
BTA: 
281601(ADCY1)
BOM: 
102267116(ADCY1)
PHD: 
102335300(ADCY1)
CHX: 
102180724(ADCY1)
OAS: 
101117327(ADCY1)
SSC: 
100624934(ADCY1)
CFR: 
BACU: 
102998650(ADCY1)
LVE: 
103081539(ADCY1)
ECB: 
100065563(ADCY1)
MYB: 
102257679(ADCY1)
MYD: 
102759978(ADCY1)
PALE: 
102887497(ADCY1)
MDO: 
100030463(ADCY1)
SHR: 
100922193(ADCY1)
GGA: 
420788(ADCY1)
TGU: 
100226080(ADCY1)
FAB: 
101807752(ADCY1)
PHI: 
102110269(ADCY1)
APLA: 
101804073(ADCY1)
FPG: 
101914769(ADCY1)
FCH: 
102056699(ADCY1)
CLV: 
102094612(ADCY1)
ASN: 
102372645(ADCY1)
AMJ: 
102573818(ADCY1)
PSS: 
102445759(ADCY1)
CMY: 
102939135(ADCY1)
ACS: 
PBI: 
XTR: 
100492373(adcy1)
DRE: 
557026(adcy1a) 569499(adcy1b)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102351204(ADCY1)
CMK: 
103187011(adcy1)
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsim_GD15838(Dsim_rut)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9140089
  Authors
Hanoune J, Pouille Y, Tzavara E, Shen T, Lipskaya L, Miyamoto N, Suzuki Y, Defer N
  Title
Adenylyl cyclases: structure, regulation and function in an enzyme superfamily.
  Journal
Mol Cell Endocrinol 128:179-94 (1997)
Reference
  Authors
Defer N, Best-Belpomme M, Hanoune J
  Title
Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase.
  Journal
Am J Physiol Renal Physiol 279:F400-16 (2000)

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