KEGG   ORTHOLOGY: K08041Help
Entry
K08041                      KO                                     
Name
ADCY1
Definition
adenylate cyclase 1 [EC:4.6.1.1]
Pathway
Purine metabolism
Calcium signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Vascular smooth muscle contraction
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
Chagas disease (American trypanosomiasis)
Amoebiasis
HTLV-I infection
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K08041  ADCY1; adenylate cyclase 1
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K08041  ADCY1; adenylate cyclase 1
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K08041  ADCY1; adenylate cyclase 1
  Cell communication
   04540 Gap junction
    K08041  ADCY1; adenylate cyclase 1
 Organismal Systems
  Immune system
   04062 Chemokine signaling pathway
    K08041  ADCY1; adenylate cyclase 1
  Endocrine system
   04911 Insulin secretion
    K08041  ADCY1; adenylate cyclase 1
   04912 GnRH signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04913 Ovarian Steroidogenesis
    K08041  ADCY1; adenylate cyclase 1
   04915 Estrogen signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04914 Progesterone-mediated oocyte maturation
    K08041  ADCY1; adenylate cyclase 1
   04916 Melanogenesis
    K08041  ADCY1; adenylate cyclase 1
  Circulatory system
   04270 Vascular smooth muscle contraction
    K08041  ADCY1; adenylate cyclase 1
  Digestive system
   04970 Salivary secretion
    K08041  ADCY1; adenylate cyclase 1
   04971 Gastric acid secretion
    K08041  ADCY1; adenylate cyclase 1
   04972 Pancreatic secretion
    K08041  ADCY1; adenylate cyclase 1
   04976 Bile secretion
    K08041  ADCY1; adenylate cyclase 1
  Nervous system
   04724 Glutamatergic synapse
    K08041  ADCY1; adenylate cyclase 1
   04727 GABAergic synapse
    K08041  ADCY1; adenylate cyclase 1
   04725 Cholinergic synapse
    K08041  ADCY1; adenylate cyclase 1
   04720 Long-term potentiation
    K08041  ADCY1; adenylate cyclase 1
   04723 Retrograde endocannabinoid signaling
    K08041  ADCY1; adenylate cyclase 1
  Environmental adaptation
   04713 Circadian entrainment
    K08041  ADCY1; adenylate cyclase 1
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    K08041  ADCY1; adenylate cyclase 1
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K08041  ADCY1; adenylate cyclase 1
  Infectious diseases
   05166 HTLV-I infection
    K08041  ADCY1; adenylate cyclase 1
   05146 Amoebiasis
    K08041  ADCY1; adenylate cyclase 1
   05142 Chagas disease (American trypanosomiasis)
    K08041  ADCY1; adenylate cyclase 1
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08041  ADCY1; adenylate cyclase 1
BRITE hierarchy
Other DBs
Genes
HSA: 
107(ADCY1)
PTR: 
463392(ADCY1)
PPS: 
100984585(ADCY1)
GGO: 
101125943(ADCY1)
PON: 
100449504(ADCY1)
MCC: 
697230(ADCY1)
MMU: 
432530(Adcy1)
RNO: 
305509(Adcy1)
CFA: 
607357(ADCY1)
AML: 
FCA: 
101101375(ADCY1)
BTA: 
281601(ADCY1)
SSC: 
100624934
MDO: 
100030463
SHR: 
100922193(ADCY1)
GGA: 
420788(ADCY1)
TGU: 
100226080(ADCY1)
ACS: 
100564004
XTR: 
100492373(adcy1)
DRE: 
557026(adcy1a) 569499(adcy1b)
TRU: 
101074661
OLA: 
101165720 101166500
DME: 
Dmel_CG9533(rut)
DPO: 
Dpse_GA29217
DAN: 
Dana_GF21594
DER: 
Dere_GG19448
DPE: 
Dper_GL20407
DSE: 
Dsec_GM12038
DSI: 
Dsim_GD15838(Dsim_rut)
DWI: 
Dwil_GK18424
DYA: 
Dyak_GE16101
DGR: 
Dgri_GH12212
DMO: 
Dmoj_GI15743
DVI: 
Dvir_GJ18604
AGA: 
AgaP_AGAP000727
AAG: 
AaeL_AAEL009022
CQU: 
CpipJ_CPIJ017287
TCA: 
661438
PHU: 
Phum_PHUM559430
ISC: 
IscW_ISCW003150
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9140089
  Authors
Hanoune J, Pouille Y, Tzavara E, Shen T, Lipskaya L, Miyamoto N, Suzuki Y, Defer N
  Title
Adenylyl cyclases: structure, regulation and function in an enzyme superfamily.
  Journal
Mol Cell Endocrinol 128:179-94 (1997)
Reference
  Authors
Defer N, Best-Belpomme M, Hanoune J
  Title
Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase.
  Journal
Am J Physiol Renal Physiol 279:F400-16 (2000)
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