KEGG   ORTHOLOGY: K08042Help
Entry
K08042                      KO                                     

Name
ADCY2
Definition
adenylate cyclase 2 [EC:4.6.1.1]
Pathway
Purine metabolism
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Gap junction
Circadian entrainment
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
HTLV-I infection
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K08042  ADCY2; adenylate cyclase 2
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04020 Calcium signaling pathway
    K08042  ADCY2; adenylate cyclase 2
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K08042  ADCY2; adenylate cyclase 2
  Cell communication
   04540 Gap junction
    K08042  ADCY2; adenylate cyclase 2
 Organismal Systems
  Immune system
   04062 Chemokine signaling pathway
    K08042  ADCY2; adenylate cyclase 2
  Endocrine system
   04911 Insulin secretion
    K08042  ADCY2; adenylate cyclase 2
   04912 GnRH signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04913 Ovarian Steroidogenesis
    K08042  ADCY2; adenylate cyclase 2
   04915 Estrogen signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04914 Progesterone-mediated oocyte maturation
    K08042  ADCY2; adenylate cyclase 2
   04921 Oxytocin signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04918 Thyroid hormone synthesis
    K08042  ADCY2; adenylate cyclase 2
   04916 Melanogenesis
    K08042  ADCY2; adenylate cyclase 2
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08042  ADCY2; adenylate cyclase 2
   04270 Vascular smooth muscle contraction
    K08042  ADCY2; adenylate cyclase 2
  Digestive system
   04970 Salivary secretion
    K08042  ADCY2; adenylate cyclase 2
   04971 Gastric acid secretion
    K08042  ADCY2; adenylate cyclase 2
   04972 Pancreatic secretion
    K08042  ADCY2; adenylate cyclase 2
   04976 Bile secretion
    K08042  ADCY2; adenylate cyclase 2
  Nervous system
   04724 Glutamatergic synapse
    K08042  ADCY2; adenylate cyclase 2
   04727 GABAergic synapse
    K08042  ADCY2; adenylate cyclase 2
   04725 Cholinergic synapse
    K08042  ADCY2; adenylate cyclase 2
   04723 Retrograde endocannabinoid signaling
    K08042  ADCY2; adenylate cyclase 2
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K08042  ADCY2; adenylate cyclase 2
  Environmental adaptation
   04713 Circadian entrainment
    K08042  ADCY2; adenylate cyclase 2
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    K08042  ADCY2; adenylate cyclase 2
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K08042  ADCY2; adenylate cyclase 2
  Infectious diseases
   05166 HTLV-I infection
    K08042  ADCY2; adenylate cyclase 2
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08042  ADCY2; adenylate cyclase 2
BRITE hierarchy
Other DBs
Genes
HSA: 
108(ADCY2)
PTR: 
461715(ADCY2)
PPS: 
100992014(ADCY2)
GGO: 
101141389(ADCY2)
PON: 
MCC: 
695328(ADCY2)
MCF: 
102130114(ADCY2)
MMU: 
210044(Adcy2)
RNO: 
81636(Adcy2)
CGE: 
HGL: 
101718304(Adcy2)
TUP: 
102492353(ADCY2)
CFA: 
478624(ADCY2)
AML: 
100473195(ADCY2)
FCA: 
101094327(ADCY2)
BTA: 
510708(ADCY2)
BOM: 
102274117(ADCY2)
PHD: 
102326467(ADCY2)
CHX: 
102171922(ADCY2)
SSC: 
100517503(ADCY2)
CFR: 
102510993(ADCY2)
ECB: 
100071337(ADCY2)
MYB: 
102260356(ADCY2)
MDO: 
100013164(ADCY2)
SHR: 
100922434(ADCY2)
OAA: 
100089708(ADCY2)
GGA: 
420935(ADCY2)
MGP: 
100540738(ADCY2)
TGU: 
100223820(ADCY2)
FAB: 
101808400(ADCY2)
PHI: 
102113898(ADCY2)
APLA: 
101803512(ADCY2)
FPG: 
101911647(ADCY2)
FCH: 
102049688(ADCY2)
CLV: 
102097532(ADCY2)
ASN: 
102383838(ADCY2)
PSS: 
102444057(ADCY2)
ACS: 
DRE: 
557902(adcy2b) 563724(adcy2a)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
BFO: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
552216(GB15583)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9140089
  Authors
Hanoune J, Pouille Y, Tzavara E, Shen T, Lipskaya L, Miyamoto N, Suzuki Y, Defer N
  Title
Adenylyl cyclases: structure, regulation and function in an enzyme superfamily.
  Journal
Mol Cell Endocrinol 128:179-94 (1997)
Reference
  Authors
Defer N, Best-Belpomme M, Hanoune J
  Title
Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase.
  Journal
Am J Physiol Renal Physiol 279:F400-16 (2000)

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