KEGG   ORTHOLOGY: K08341Help
Entry
K08341                      KO                                     

Name
GABARAP, ATG8, LC3
Definition
GABA(A) receptor-associated protein
Pathway
ko04068  FoxO signaling pathway
ko04136  Autophagy - other
ko04137  Mitophagy - animal
ko04138  Autophagy - yeast
ko04139  Mitophagy - yeast
ko04140  Autophagy - animal
ko04212  Longevity regulating pathway - worm
ko04371  Apelin signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04727  GABAergic synapse
ko05167  Kaposi's sarcoma-associated herpesvirus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04371 Apelin signaling pathway
    K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
   04068 FoxO signaling pathway
    K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
   04138 Autophagy - yeast
    K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
   04136 Autophagy - other eukaryotes
    K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
   04137 Mitophagy - animal
    K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
   04139 Mitophagy - yeast
    K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
 Organismal Systems
  Immune system
   04621 NOD-like receptor signaling pathway
    K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
  Nervous system
   04727 GABAergic synapse
    K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
  Aging
   04212 Longevity regulating pathway - worm
    K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
 Human Diseases
  Infectious diseases
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
Membrane trafficking [BR:ko04131]
 Autophagy
  Autophagosome formation proteins
   Atg8 conjugation proteins
    K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
Ubiquitin system [BR:ko04121]
 Ubiquitins and Ubiquitin-like proteins
  Ubiquitin-like proteins (UBLs)
   K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Autophagy-related proteins
    K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
BRITE hierarchy
Genes
HSA: 11337(GABARAP) 11345(GABARAPL2) 23710(GABARAPL1)
PTR: 454251(GABARAPL2) 467760 737951(GABARAPL1) 748888(GABARAP)
PPS: 100973730(GABARAPL2) 100980803 100989538(GABARAP) 100992751(GABARAPL1)
GGO: 101126737 101136984 101141496(GABARAPL2) 101146727(GABARAP) 101154391(GABARAPL1)
PON: 100174231(GABARAPL1) 100440271(GABARAPL2) 100445631 100455475(GABARAP)
NLE: 100580511 100586489(GABARAP) 100595852 100605176(GABARAPL2) 100605322(GABARAPL1)
MCC: 695627 702827 714413(GABARAPL2) 714597(GABARAP) 717640(GABARAPL1)
MCF: 101864971(GABARAPL1) 101925587(GABARAPL2) 102145217(GABARAP) 107130295
CSAB: 103218578(GABARAPL1) 103231198 103233317(GABARAPL2) 103242281(GABARAP)
RRO: 104668619(GABARAPL1) 104669306 104673331(GABARAP) 104677847(GABARAPL2) 104679279 104682176
RBB: 108514304(GABARAP) 108517211 108527415(GABARAPL2) 108542138(GABARAPL1) 108545090
CJC: 100393860(GABARAPL2) 100399942(GABARAPL1) 100404267(GABARAP) 108591978
SBQ: 101031788(GABARAP) 101043061(GABARAPL2) 101045502(GABARAPL1)
MMU: 56486(Gabarap) 57436(Gabarapl1) 93739(Gabarapl2)
RNO: 100359937 58974(Gabarap) 64670(Gabarapl2) 689161(Gabarapl1)
CGE: 100767236(Gabarap) 100767407(Gabarapl2) 100771320(Gabarapl1)
NGI: 103725661(Gabarapl2) 103745480(Gabarapl1) 103752156(Gabarap)
HGL: 101706208(Gabarapl2) 101710547(Gabarapl1) 101711840(Gabarap)
CCAN: 109674552(Gabarap) 109684019(Gabarapl2) 109689711(Gabarapl1)
OCU: 100008883(GABARAP) 100340751(GABARAPL1) 100342698(GABARAPL2)
TUP: 102485172(GABARAP) 102485377(GABARAPL1) 102501394 102502678(GABARAPL2)
CFA: 479479(GABARAP) 479646(GABARAPL2) 612919(GABARAPL1)
AML: 100471461(GABARAPL1) 100480205(GABARAPL2) 100480510(GABARAP)
UMR: 103660349(GABARAP) 103662121(GABARAPL2) 103669133(GABARAPL1)
ORO: 101367890(GABARAPL1) 101368575(GABARAPL2) 101374677(GABARAP)
FCA: 101083945(GABARAPL1) 101094636(GABARAP) 101097365(GABARAPL2)
PTG: 102953160(GABARAPL1) 102961103(GABARAPL2) 102967161(GABARAP)
AJU: 106965636(GABARAPL1) 106972484(GABARAP) 106983422(GABARAPL2)
BTA: 282531(GABARAPL2) 327715(GABARAP) 338472(GABARAPL1)
BOM: 102265036(GABARAPL2) 102273006(GABARAP) 102276167(GABARAPL1)
BIU: 109559670(GABARAPL1) 109572143(GABARAPL2) 109573765(GABARAP)
PHD: 102326390(GABARAPL1) 102340902 102342820(GABARAP)
CHX: 100861246(GABARAPL2) 102182439(GABARAP) 102184507(GABARAPL1)
OAS: 101117406(GABARAPL1) 101118285(GABARAP) 101118469(GABARAPL2)
SSC: 100462751(GABARAPL1) 100462752(GABARAP) 100521968(GABARAPL2)
CFR: 102512965(GABARAPL1) 102517242(GABARAP) 102524238(GABARAPL2)
CDK: 105084211(GABARAPL2) 105094216(GABARAPL1) 105103045(GABARAP)
BACU: 102998079(GABARAPL2) 102999754(GABARAP) 103008527(GABARAPL1)
LVE: 103076028(GABARAPL2) 103079501(GABARAP) 103081682 103086727 103091447(GABARAPL1)
OOR: 101269256(GABARAPL1) 101274009(GABARAP) 101288065(GABARAPL2)
ECB: 100053911(GABARAPL1) 100055295(GABARAPL2) 111775730(GABARAP)
EPZ: 103553031(GABARAPL2) 103557741(GABARAP) 103560603(GABARAPL1)
EAI: 106835297(GABARAPL2) 106837407(GABARAPL1) 106844180(GABARAP)
MYB: 102255361(GABARAPL2) 102259347(GABARAP) 102262056(GABARAPL1)
MYD: 102755892(GABARAPL1) 102768297(GABARAPL2) 102775333(GABARAP)
HAI: 109375276(GABARAPL1) 109384803(GABARAPL2) 109394622(GABARAP)
RSS: 109434105(GABARAPL2) 109435563(GABARAPL1) 109443152 109443191 109443243 109443246 109454458(GABARAP)
PALE: 102878715(GABARAPL1) 102880702(GABARAP) 102895647(GABARAPL2)
LAV: 100658035(GABARAP) 100659994(GABARAPL1) 100675686(GABARAPL2)
MDO: 100010204 100016545(GABARAP) 100019121(GABARAPL1) 100029139(GABARAPL2)
SHR: 100930358(GABARAP) 100931278(GABARAPL2) 100931419(GABARAPL1)
OAA: 100077391(GABARAPL2) 100083105(GABARAP) 100085684
GGA: 107050619(GABARAP) 769118(GABARAPL1) 770240(GABARAPL2)
MGP: 100544791(GABARAPL1) 100551271(GABARAPL2)
CJO: 107307380(GABARAP) 107319320(GABARAPL1) 107319475(GABARAPL2)
APLA: 101791448(GABARAPL1) 106019872(GABARAPL2)
ACYG: 106046295(GABARAPL1) 106046608(GABARAPL2)
TGU: 100190406(GABARAPL2) 100228739 100228782(GABARAPL1)
GFR: 102039558(GABARAPL1) 102043479(GABARAPL2)
FAB: 101806792(GABARAPL1) 101814814(GABARAPL2)
PHI: 102107990(GABARAPL2) 102114461(GABARAP) 102114705(GABARAPL1)
PMAJ: 107204943(GABARAPL1) 107209781(GABARAPL2)
CCW: 104691966(GABARAPL2) 104696137(GABARAPL1)
FPG: 101910696(GABARAPL2) 101919137(GABARAPL1)
FCH: 102047079(GABARAPL1) 102058869(GABARAPL2)
CLV: 102083846(GABARAPL2) 102088161(GABARAPL1)
EGZ: 104124202(GABARAPL1) 104126292(GABARAPL2)
AAM: 106497285(GABARAPL1) 106498800(GABARAPL2)
ASN: 102367983(GABARAPL2) 102382529(GABARAPL1) 102385155(GABARAP)
AMJ: 102561148(GABARAPL1) 102563058(GABARAP) 102571206(GABARAPL2)
PSS: 102444496(GABARAP) 102449838(GABARAPL2) 102460066(GABARAPL1)
CMY: 102944349(GABARAPL1) 102946635(GABARAPL2)
CPIC: 101938292(GABARAPL1) 101938520(GABARAPL2)
ACS: 100558896(gabarapl2) 100564768(gabarapl1)
PVT: 110076328(GABARAPL2) 110082372(GABARAP) 110090845
PBI: 103057849 103061483(GABARAPL2)
GJA: 107109670(GABARAPL1) 107118080(GABARAP) 107124703(GABARAPL2)
XLA: 108715442 414477(gabarap.L) 443979(gabarapl1.L) 494762(gabarapl1-b) 734814(gabarapl2.L)
XTR: 100125141(gabarapl2) 496614(gabarapl1) 595040(gabarapl1)
NPR: 108786558(GABARAPL2) 108795396
DRE: 326974(gabarapa) 403036(gabarapl2) 793200(gabarapb)
IPU: 108260203(Gabarap) 108266696(gabarapl1) 108268088(gabarap) 108268593(gabarapl2)
TRU: 101066427(gabarap) 101067923(gabarapl2) 101076880 101076890
LCO: 104923964(gabarap) 104929025 104933813(gabarapl2) 104937788
NCC: 104945426(gabarap) 104950885(gabarapl2) 104960404 104963252
MZE: 101467473 101471919(gabarapl2) 101473761 101483169(gabarap)
XMA: 102217957 102218600 102219827(gabarap) 102223011(gabarapl2)
PRET: 103460102 103466299(gabarapl2) 103478027 103480454(gabarap)
NFU: 107377387(gabarap) 107379424 107381527 107389278(gabarapl2)
CSEM: 103378875 103379687(gabarapl2) 103387166(gabarap) 103388004
HCQ: 109514343(gabarapl2) 109515317 109518372(gabarap)
BPEC: 110159433(gabarap) 110162996 110172754(gabarapl2)
SASA: 100195594(grl1) 100217350(gbrap) 106573663(gabarapl2) 106576832(GRL1) 106577557(GBRAP) 106587940(GBRL2) 106594419(GBRL2) 106602900(GBRAP)
ELS: 105008592 105019048 105019088 105020670(gabarap) 105029592(gabarapl2)
LCM: 102348715(GABARAPL1) 102356442 102357322(GABARAPL2)
CMK: 103175978(gabarapl2)
SKO: 100329086(GABArap) 100369145
DME: Dmel_CG12334(Atg8b) Dmel_CG32672(Atg8a)
DSI: Dsimw501_GD16015(Dsim_GD16015) Dsimw501_GD20217(Dsim_GD20217)
MDE: 101899569
AAG: 5568843
AME: 725184(Atg8a)
BIM: 100747870
BTER: 100645690
SOC: 105208115
AEC: 105153010
ACEP: 105627469
PBAR: 105429650
HST: 105189537
CFO: 105256213
LHU: 105671268
PGC: 109858618
NVI: 100679003
TCA: 661847
DPA: 109540010
NVL: 108558321
BMOR: 692938(Atg8)
PMAC: 106719220
PRAP: 110992141
PXY: 105386445
API: 100163628
DNX: 107167856
ZNE: 110840790
FCD: 110852530
CEL: CELE_C32D5.9(lgg-1)
CBR: CBG02633(Cbr-lgg-1)
BMY: Bm1_46715
SHX: MS3_01397
ATH: AT1G62040(ATG8C) AT2G05630(ATG8D) AT2G45170(ATG8E) AT3G06420(ATG8H) AT3G15580(APG8H) AT3G60640(ATG8G) AT4G04620(ATG8B) AT4G16520(ATG8F) AT4G21980(APG8A)
LJA: Lj0g3v0317029.1(Lj0g3v0317029.1) Lj6g3v1873610.1(Lj6g3v1873610.1)
INI: 109152067(InATG8e) 109159730(InATG8) 109165702 109169989(InATG8a) 109188337(InATG8c) 109189748(InATG8d) 109190624(InATG8b)
DOSA: Os04t0624000-01(Os04g0624000) Os07t0512200-01(Os07g0512200) Os08t0191600-01(Os08g0191600)
ATS: 109762315(LOC109762315) 109777624(LOC109777624) 109787644(LOC109787644)
ZMA: 100240694(pco136400) 100240695(IDP1471) 100240696(Atg8c) 100240697(Atg8d) 100240698(Atg8e) 109939387
CRE: CHLREDRAFT_59275(APG8)
VCN: VOLCADRAFT_75248(apg8)
MIS: MICPUN_109644(ATG8)
APRO: F751_5121
SCE: YBL078C(ATG8)
ERC: Ecym_4675
KMX: KLMA_80372(ATG8)
NCS: NCAS_0E02560(NCAS0E02560)
NDI: NDAI_0A01580(NDAI0A01580) NDAI_0E04130(NDAI0E04130)
TPF: TPHA_0E00800(TPHA0E00800)
TBL: TBLA_0I00380(TBLA0I00380)
TDL: TDEL_0C01470(TDEL0C01470)
KAF: KAFR_0K01880(KAFR0K01880) KAFR_0L01800(KAFR0L01800)
PIC: PICST_34219(ATG8)
CAL: CAALFM_C105700WA(AUT7)
CAUR: QG37_01246
NCR: NCU01545(atg-8)
NTE: NEUTE1DRAFT117293(NEUTE1DRAFT_117293)
MGR: MGG_01062
MAW: MAC_08764
MAJ: MAA_02674
CMT: CCM_07484
MBE: MBM_02287
ANI: AN5131.2
ANG: ANI_1_1284064(An07g10020)
ABE: ARB_04224
TVE: TRV_01085
PTE: PTT_13883
SPO: SPBP8B7.24c(atg8)
CNE: CNA07930
CNB: CNBA7760
ABP: AGABI1DRAFT111526(AGABI1DRAFT_111526)
ABV: AGABI2DRAFT190754(AGABI2DRAFT_190754)
MGL: MGL_2013
DFA: DFA_07329 DFA_08591(atg8)
PFA: PF10_0193
PYO: PY17X_0505200(PY00606)
PCB: PCHAS_050420(PC000787.01.0)
TAN: TA12615
BBO: BBOV_III005950(17.m10557)
SMIN: v1.2.014766.t1(symbB.v1.2.014766.t1) v1.2.014767.t1(symbB.v1.2.014767.t1) v1.2.037659.t1(symbB.v1.2.037659.t1)
SPAR: SPRG_14437
TBR: Tb927.7.5900(Tb07.10C21.50) Tb927.7.5910(Tb07.10C21.40)
TCR: 508173.47
LMA: LMJF_19_1630(ATG8)
LIF: LINJ_19_0820(ATG8B.1) LINJ_19_0850(ATG8B.2) LINJ_19_0860(ATG8B.3) LINJ_19_1660(ATG8)
LBZ: LBRM_19_1170(ATG8B.1) LBRM_19_1180(ATG8B.2) LBRM_19_1890(ATG8)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Amar N, Lustig G, Ichimura Y, Ohsumi Y, Elazar Z
  Title
Two newly identified sites in the ubiquitin-like protein Atg8 are essential for autophagy.
  Journal
EMBO Rep 7:635-42 (2006)
DOI:10.1038/sj.embor.7400698
  Sequence
[sce:YBL078C]
Reference
PMID:9892355
  Authors
Wang H, Bedford FK, Brandon NJ, Moss SJ, Olsen RW
  Title
GABA(A)-receptor-associated protein links GABA(A) receptors and the cytoskeleton.
  Journal
Nature 397:69-72 (1999)
DOI:10.1038/16264
  Sequence
[hsa:11337]

DBGET integrated database retrieval system